Links to all GeneRIF Items | 468 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 23975372 (ATF4) | These results indicate that increased expression of p-ATF4 (ser 245) may contribute to cancer development of non-small cell lung cancer and may be a potential cancer marker. |
| 31551255 (ATF4) | In response to extracellular amino acid limitation, lung adenocarcinoma cells with diverse genotypes commonly induce ATF4 in an eIF2alpha-dependent manner, which can be blocked pharmacologically using an ISR inhibitor. Although suppressing eIF2alpha or ATF4 can trigger different biological consequences, adaptive cell-cycle progression and cell migration are particularly sensitive to inhibition of the ISR. |
| 31862913 (ATF4) | TIPRL potentiates survival of lung cancer by inducing autophagy through the eIF2alpha-ATF4 pathway. |