Links to all GeneRIF Items | 4521 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 12757855 (NUDT1) | Elevated levels of hMTH1 protein is asociated with non-small-cell lung carcinomas |
| 16774934 (NUDT1) | In a case-control study, single nucleotide polymorphism of MTH1 was associated with increased small cell lung cancer risk. |
| 29661172 (NUDT1) | overall our cell viability data indicates that targeting MTH1 will likely not be an across-the-board effective non-small cell lung cancer therapeutic strategy; rather it induces non-cytotoxic DNA damage that could promote cancer heterogeneity and evolution. |
| 31311767 (NUDT1) | MTH1-specific 8-oxodGTPase activity is a hallmark of cancer in colon, lung and pancreatic tissue |
| 33096144 (NUDT1) | The high expression of MTH1 and NUDT5 promotes tumor metastasis and indicates a poor prognosis in patients with non-small-cell lung cancer. |