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Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

4103

PubMed (Gene Name)

Literature evidence

16596224 (MAGEA4)

expression may represent potential targets for cancer immunotherapy in patients with non small cell lung carcinoma.

18982744 (MAGEA4)

Its expression is significantly associated with prognostic factors in poor outcome of the non-small cell lung cancer.

19545928 (MAGEA4)

positive expression in patients with non-small cell lung cancer is associated with poorer overall survival

22134685 (MAGEA4)

Report MAGEA1-A6 expression in sputum suggests presence of lung cancer cells or precancerous cells.

23124547 (MAGEA4)

HLA class I loss in smokers or patients with the MAGE-A4 gene was a prognostic factors in non-small cell lung cancer .

26191258 (MAGEA4)

CTAs (MAGE-A4, NY-ESO-1, MAGE-A10) were more likely expressed in patients with squamous cell carcinoma of the lung and when CTAs combined with CD133, they can be better prognostic factors.

27793776 (MAGEA4)

High MAGE-A4 expression is associated with lung cancer.

29901069 (MAGEA4)

Study shows that whereas MAGEA4 expression by itself may be indicative of a poor prognosis in primary lung cancer, its prognostic value depends entirely on its subcellular localization and on the p53 status. The accumulation of nuclear MAGEA4 expression without p53 expression is significantly associated with poor survival, implying that MAGEA4 inhibits apoptosis and increases tumorigenesis.