Links to all GeneRIF Items | 3952 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 12200109 (LEP) | leptin has a role in advanced lung cancer, but is not causative in cancer cachexia or anorexia |
| 19033693 (LEP) | Oserved higher serum leptin levels may represent a tumor-promoting event during non-small-cell lung carcinogenesis. |
| 21927908 (LEP) | The expression of leptin, OB-Rb and HER-2 was significantly higher in non-small-cell lung cancer (NSCLC) tissues than in normal lung tissues. The expression of leptin is an independent prognostic factor for NSCLC. |
| 23430445 (LEP) | Leptin serum levels may provide useful prognostic information in lung cancer patients. The leptin/adiponectin ratio is significantly lower in patients compared to controls. |
| 24355691 (LEP) | Determination of leptin levels might provide useful predictive information for lung cancer. |
| 24758911 (LEP) | Leption and LepR signal transduction pathways plays important in non-small cell lung cancer.[review] |
| 25027400 (LEP) | susceptibility effects of LEP -2548G > A polymorphism alone or in combination with LEPR Q223R polymorphism on lung cancer were observed |
| 28160559 (LEP) | High leptin serum level is associated with lung cancer. |
| 28643734 (LEP) | SLL might be beneficial as a useful biomarker in preclinical setting of NSCLC to guide detecting the lung cancer subtypes as well as monitoring the patients |
| 31119158 (LEP) | Leptin produced by cancer-associated fibroblasts promotes proliferation and migration of non-small-cell lung cancer cells probably via PI3K/AKT and MAPK/ERK1/2 signaling pathways in a paracrine manner. |