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Cancer metastasis database

Annotation category 5

Expression and regulation

Regulation From TransFac database

leptin(h) --> Shc-1-p46(h){pY} (increase of phosphorylation)
leptin(h) --> Shc-1-p52(h){pY} (increase of phosphorylation)
leptin(h) --> Shc-1(h):Grb-2(h) (increase of binding)
leptin(h) --> ERK(h){p} (increase of phosphorylation)
leptin(h) --> LIF(h) (increase of secretion)
LEP(h) --> leptin(h) (expression).
HKIII(r) + leptin(h) <==> HKIII(r):leptin(h) (binding)
leptin(h) --> AMPKalpha-2(h){pT172} (increase of phosphorylation)
leptin(h) --> AMPKalpha-1(h){pT172} (increase of phosphorylation)
leptin(h) --> PPARA(m) (transactivation)
leptin(h) + lepr-A(m) <==> leptin(h):lepr-A(m) (binding)
leptin(h) --> STAT3(h){pY} (increase of phosphorylation)
leptin(h) --> CKII-beta(m) (increase of abundance)
leptin(h) --> STAT3(h){p} (increase of phosphorylation)
leptin(h) --> IRS-1(h){pY} (increase of phosphorylation)
leptin(h) --> Sam68(h){pY} (increase of phosphorylation)
leptin(h) --> ERK1(h){pT}{pY} (increase of phosphorylation)
leptin(h) --> ERK2(h){pT}{pY} (increase of phosphorylation)
leptin(h) --> STAT3(h){pY705} (increase of phosphorylation)
leptin(h) --> CCND1(h) (transactivation)
leptin(h) --> SOCS1(h) (transactivation)
leptin(h) --> SOCS3(h) (transactivation)
leptin(h) --/ SLC2A4(h) (transrepression)
leptin(h) --/ IRS1(h) (transrepression)
leptin(h) --/ ADIPOQ(h) (transrepression)
leptin(h) --/ FASN(h) (transrepression)
leptin(h) --/ LPL(h) (transrepression)
leptin(h) --/ LIPE(h) (transrepression)
leptin(h) --/ PPARG(h) (transrepression)
leptin(h) --> ERK1(h){pT202}{pY204} (increase of phosphorylation)
leptin(h) --> ERK2(h){pT185}{pY187} (increase of phosphorylation)
leptin(h) --> p38(h){pT}{pY} (increase of phosphorylation)
leptin(h) --> JNK(h){pT}{pY} (increase of phosphorylation)
leptin(h) + lepr-E(h) <==> leptin(h):lepr-E(h) (binding)
leptin(h) + lepr(h) <==> leptin(h):lepr(h) (binding)
leptin(h) --/ STAR(h) (transrepression)
LEP(h) --> leptin(h) (expression).

Human Primary Tumor Samples (U95)  | Top

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Human U133A/GNF1H Gene Atlas  | Top