Links to all GeneRIF Items | 3565 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 12517954 (IL4) | IL-4-stimulated A549 lung adenocarcinoma cells are committed to apoptosis via the caspase-3 pathway involving the binding of 15(S)-HETE to PPAR gamma transcription factor, the down-regulation of Bcl-XL, and the resultant overexpression of Bax. |
| 14634100 (IL4) | IL-4 up-regulates SOCS-1 expression in A549 human lung adenocarcinoma cells by stimulating interaction of STAT6 with three interferon-gamma-activated sequence (GAS) motifs in the SOCS-1 promoter. |
| 22142023 (IL4) | Interleukin-4 -590T/C polymorphism influences the susceptibility to nonsmall cell lung cancer. |
| 22583827 (IL4) | IL-4 promoter polymorphism is associated with non-small cell lung cancer. |
| 26504066 (IL4) | The TT genotype of IL-4 C-589T compared to the CC wild-type genotype may have a protective effect on lung cancer risk. |
| 30729744 (IL4) | GWA study indicated potential associations between IL-4 polymorphisms and lung cancer susceptibility in China. |
| 31798581 (IL4) | Activation of the IL-4/STAT6 Signaling pathway Promotes lung cancer Progression by Increasing M2 Myeloid Cells. |
| 24325354 (Il4) | Umbelliprenin induced production of IFN-gamma and TNF-alpha, and reduced IL-10, IL-4, Foxp3 and TGF-beta in a mouse model of lung cancer. |