| IL-4(h) + IL-4Ralpha(h) <==> IL-4(h):IL-4Ralpha(h) (binding)
|
IL-4(h) + IL-4Ralpha(h) + IL-13Ralpha1(h) <==> IL-4(h):IL-4Ralpha(h):IL-13Ralpha1(h) (binding)
|
IL-4(h) --> Jak1(h){pY} (increase of phosphorylation)
|
IL-4(h) --> Jak3(h){pY} (increase of phosphorylation)
|
IL-4(h) --> STAT6(h){pY} (increase of phosphorylation)
|
IL-4(h) --> JNK1(h){p} (increase of phosphorylation)
|
IL-4(h) --> p38alpha(h){p} (increase of phosphorylation)
|
IL-4(h) --> ERK(h){p} (increase of phosphorylation)
|
IL-4(h) --> CS1(h) (increase of abundance)
|
IL-4(h) --> STAT3(h){pY705} (increase of phosphorylation)
|
IL-4(h) --> CRP(h) (transactivation)
|
IL-4(h) --> IL-4(h) (expression).
|
IFNgamma(h) --> IL-4(h) (increase of secretion)
|
IL-4-isoform1(h) --> STAT6(h){pS}{pY} (increase of phosphorylation)
|
IL-4-isoform1(h) --> STAT6(mo){pS}{pT}{pY} (increase of phosphorylation)
|
IL-4(h) --> IL-4-isoform1(h) (expression).
|
IL-4(h) --> IL-4-isoform2(h) (expression).
|
