Links to all GeneRIF Items | 27122 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 11814687 (DKK3) | REIC gene expression was decreased in 14 of 24 fresh non-small cell lung cancer specimens (58%) compared to that in corresponding non-cancerous tissue. |
| 18048388 (DKK3) | Ectopic expression of Dkk3 in lung cancer cells with Dkk3 hypermethylation induced apoptosis and inhibited TCF-4 activity as well as nuclear accumulation of beta-catenin and expression of TCF-4 targets c-Myc and cyclin D1 |
| 24498395 (DKK3) | Loss of REIC expression is associated withnon-small cell lung cancer. |
| 25573172 (DKK3) | reactivation of Dkk3 enhances the chemosensitivity to cisplatin in cisplatinresistant lung adenocarcinoma cell lines |
| 25760729 (DKK3) | Epigenetic downregulation of DKK3 leads to docetaxel resistance in human nonsmall cell lung cancer (NSCLC) cells. |
| 26457595 (DKK3) | A decreased risk of lung cancer was found for the genotype combination of DKK3 and sFRP4. |
| 29341059 (DKK3) | These findings suggested that the down-regulated REIC expression might be involved in lung carcinogenesis due to its promoter methylation |
| 31682048 (DKK3) | These results suggest that DKK3 plays a role in the progression of lung adenocarcinoma by promoting cell adhesion and invasion. |