Links to all GeneRIF Items | 26524 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 15265683 (LATS2) | Lats2 induces apoptosis through downregulating anti-apoptotic proteins, BCL-2 and BCL-x(L), in human lung cancer cells. |
| 19008013 (LATS2) | tumor-specific mutations and down-regulation of the gene expression is observed in non-small cell lung carcinoma patients |
| 24976335 (LATS2) | LATS2 expression level is predictive of survival in patients with resected lung AD. LATS2 may modulate and contribute to tumor growth via different signaling pathways in EGFR mutant and wild-type tumors. |
| 25946971 (LATS2) | Loss of LATS2 expression is associated with lung cancer. |
| 27195672 (LATS2) | Upregulated long non-coding RNA AGAP2-AS1 represses LATS2 and KLF2 expression through interacting with EZH2 and LSD1 in non-small-cell lung cancer cells. |
| 27470365 (LATS2) | overexpression of LATS2 resulted in mobility inhibition in non-small cell lung cancer cell lines A549 and H1299, and reduced protein level of matrix metalloproteinase-2 (MMP-2) and MMP-9. |
| 30551520 (LATS2) | LATS2 is a tumor suppressor of lung cancer via triggering mitochondrial fission and activation of the JNK-Mff signaling pathway. |
| 31646568 (LATS2) | LINC00511 promotes the progression of non-small cell lung cancer through downregulating LATS2 and KLF2 by binding to EZH2 and LSD1. |
| 31820862 (LATS2) | downregulated LATS2 expression may predict aggressive biologic behavior and a worse prognosis in non-small cell lung carcinoma |
| 32534707 (LATS2) | Hippo pathway and tumoral FOXP3 expression correlate with tumor growth in squamous cell carcinoma of the lung. |