the effect of 4.1B deficiency on tumor suppressor in lung cancer-1 distribution were also investigated using rodent pheochromocytoma and 4.1B-knockout mice.

this study sought to investigate if tumour suppressor in lung cancer-1 (TSLC1) expression could be used to predict outcome in dogs with mast cell tumours.

These results suggest that aberrant Tslc1 gene methylation may be involved in BHP-induced development of lung adenocarcinomas in rats.

alteration of TSLC1 expression by romoter methylation is involved in advanced nonsmall cell lung cancer

TSLC1 represents central effector gene for controlling biological aggressiveness of pulmonary adenocarcinoma and is essential biomarker for predicting prognosis

lung tumor suppressor gene,TSLC1, associates with MPP3, a human homologue of Drosophila tumor suppressor Dlg.

A549 lung cancer cells expressing wild-type TSLC1 showed suppression of anchorage-independent colony formation in soft agar and markedly increased cell-cell adhesion activity.

Loss of TSLC1 is associated with lower patient survival, supporting its role as a tumor suppressor in lung adenocarcinoma.

methylation of TSLC1 leading to loss of the expression, is an important event in the pathogenesis of non-small-cell lung cancer

While overexpression of CADM1 was observed on the cell surface of adenocarcinomas at a high frequency, around 60%, positive stainings were rarely observed on that of other lung carcinomas including squamous cell carcinomas.

promoter methylation is unlikely to have diagnostic value for the early detection of lung cancer

The expressions of TSLC1 and 4.1B in non-small cell lung cancer tissues were significantly lower than that in adjacent lung tissues.

Structural basis of tumor suppressor in lung cancer 1 (TSLC1) binding to differentially expressed in adenocarcinoma of the lung (DAL-1/4.1B).

Loss/Down-regulation of tumor suppressor in lung cancer 1 expression is associated with ovarian tumor progression

findings suggest that CADM1 enhances the malignant features of small cell lung cancer, as is observed in adult T-cell leukemia, and could provide a molecular marker specific to small cell lung cancer

Infection of NCI-H460, A549, and H1299 lung cancer cells with Ad.sp-E1A(Delta24)-TSLC1 induced apoptosis.

Data suggest that tumor suppressor in lung cancer 1 (TSLC1) as tumor suppressor may play prominent roles in development and progression of cutaneous squamous cell carcinoma (CSCC) via regulation of different biological processes.