Links to all GeneRIF Items | 23327 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 30967264 (Nedd4l) | Knocking down of NEDD4L promotes non-small cell lung cancer metastasis in mice. |
| 23812770 (NEDD4L) | Low NEDD4L expression is associated with non-small cell lung cancer. |
| 26581907 (NEDD4L) | overexpression of miR-93 in lung cancer cells promoted TGF-b-induced EMT through downregulation of NEDD4L. The analysis of publicly available gene expression array datasets indicates that low NEDD4L expression correlates with poor outcomes among patients with lung cancer, further supporting the oncogenic role of miR-93 in lung tumorigenesis and metastasis. |
| 30967264 (NEDD4L) | Downregulation of NEDD4L is found in non-small cell lung cancer samples compared with normal samples. NEDD4L low expression could be an independent prognostic factor. NEDD4L suppresses cell proliferation and metastasis in vitro and in vivo. |
| 31618441 (NEDD4L) | Novel genetic variants in KIF16B and NEDD4L in the endosome-related genes are associated with nonsmall cell lung cancer survival. |