Links to all GeneRIF Items | 2324 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 16116610 (FLT4) | Overexpression of vascular endothelial growth factor receptor 3 is associated with lung adenocarcinoma |
| 16755294 (FLT4) | The VEGF-3/VEGFR-c ratio was positively associated with lymph node metastasis in non-small cell lung cancer . |
| 17686546 (FLT4) | In non-small-cell lung cancer cells, VEGF-C/VEGFR-3 coexpression suggests an autocrine/paracrine loop responsible for a high proliferation rate in tumour cells. |
| 18292935 (FLT4) | Under hypoxic conditions an autocrine loop between VEGF-C/VEGFR-3 and HIF-1 alpha is possible in breast carcinoma and lung carcinoma but not in colorectal carcinoma cell lines. |
| 19240177 (FLT4) | High VEGFR-3-positive circulating lymphatic/vascular endothelial progenitor cell level is associated with small cell lung cancer. |
| 21680174 (FLT4) | RNAi-mediated silencing of VEGF-C inhibits non-small cell lung cancer progression by simultaneously down-regulating the CXCR4, CCR7, VEGFR-2 and VEGFR-3-dependent axes-induced ERK, p38 and AKT signalling pathways. |
| 31878999 (FLT4) | High expression of VEGFR3 in the lung adenocarcinoma tissue is positively correlated with poor prognosis. |