lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	2324
Symbol	FLT4
Synonymous	FLT41\|LMPH1A\|PCL\|VEGFR3
Full name	fms-related tyrosine kinase 4
Gene description	FLT-4\|VEGFR-3\|fms-like tyrosine kinase 4\|soluble VEGFR3 variant 1\|soluble VEGFR3 variant 2\|soluble VEGFR3 variant 3\|tyrosine-protein kinase receptor FLT4\|vascular endothelial growth factor receptor 3
Cytoband	5q35.3
Gene type	protein-coding
Synonymous	MIM:136352; HGNC:HGNC:3767; Ensembl:ENSG00000037280; HPRD:00636; Vega:OTTHUMG00000130931

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.1267_1268insC; p.Q423fs*4; 5:180626022-180626023	lung	carcinoma; small_cell_carcinoma	Insertion - Frameshift
c.3039T>G; p.D1013E; 5:180616957-180616957	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2667G>A; p.E889E; 5:180619347-180619347	breast	carcinoma	Substitution - coding silent
c.1267_1268insC; p.Q423fs*4; 5:180626022-180626023	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1317C>A; p.S439R; 5:180625973-180625973	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.852C>T; p.S284S; 5:180629392-180629392	skin	malignant_melanoma	Substitution - coding silent
c.383C>T; p.S128F; 5:180630572-180630572	NS	malignant_melanoma	Substitution - Missense
c.383C>T; p.S128F; 5:180630572-180630572	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3078G>T; p.E1026D; 5:180616918-180616918	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3499G>T; p.E1167*; 5:180612544-180612544	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.735_736GG>AA; p.E246K; 5:180629776-180629777	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.969C>T; p.T323T; 5:180629275-180629275	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1103G>A; p.W368*; 5:180628882-180628882	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.975C>A; p.V325V; 5:180629269-180629269	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1165G>A; p.V389M; 5:180626204-180626204	skin	malignant_melanoma	Substitution - Missense
c.1695C>T; p.S565S; 5:180621867-180621867	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1695C>T; p.S565S; 5:180621867-180621867	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.210C>A; p.T70T; 5:180630745-180630745	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.3204C>A; p.Y1068*; 5:180616382-180616382	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Nonsense
c.1253T>A; p.V418E; 5:180626116-180626116	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.576C>T; p.L192L; 5:180630043-180630043	skin	malignant_melanoma	Substitution - coding silent
c.3204C>A; p.Y1068*; 5:180616382-180616382	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.1894C>T; p.R632C; 5:180621668-180621668	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.3392G>A; p.G1131D; 5:180613050-180613050	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.916G>A; p.G306S; 5:180629328-180629328	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.521C>T; p.S174L; 5:180630098-180630098	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2069A>G; p.N690S; 5:180621204-180621204	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2248G>A; p.V750M; 5:180620927-180620927	central_nervous_system; brain	glioma	Substitution - Missense
c.1536G>A; p.E512E; 5:180623947-180623947	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.3687-2A>T; p.?; 5:180610027-180610027	lung	carcinoma; adenocarcinoma	Unknown
c.2069A>G; p.N690S; 5:180621204-180621204	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3198C>T; p.P1066P; 5:180616388-180616388	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3198C>T; p.P1066P; 5:180616388-180616388	thyroid	other; neoplasm	Substitution - coding silent
c.3820G>T; p.D1274Y; 5:180609041-180609041	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3198C>T; p.P1066P; 5:180616388-180616388	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.963_967delGAGCA; p.E321fs*7; 5:180629277-180629281	bone; femur	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Deletion - Frameshift
c.1726C>A; p.L576M; 5:180621836-180621836	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3239G>A; p.W1080*; 5:180614160-180614160	skin	malignant_melanoma	Substitution - Nonsense
c.2341G>A; p.G781S; 5:180620674-180620674	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3082C>G; p.L1028V; 5:180616914-180616914	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.89delC; p.P30fs*3; 5:180631748-180631748	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.89delC; p.P30fs*3; 5:180631748-180631748	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3174T>A; p.L1058L; 5:180616412-180616412	skin	malignant_melanoma	Substitution - coding silent
c.375C>T; p.A125A; 5:180630580-180630580	skin	malignant_melanoma	Substitution - coding silent
c.1133G>A; p.R378H; 5:180626236-180626236	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1525G>A; p.E509K; 5:180623958-180623958	skin	malignant_melanoma	Substitution - Missense
c.1895G>T; p.R632L; 5:180621667-180621667	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3278C>T; p.T1093M; 5:180614121-180614121	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.332G>A; p.C111Y; 5:180630623-180630623	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.554G>A; p.W185*; 5:180630065-180630065	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.3538-2A>T; p.?; 5:180611481-180611481	lung; right_upper_lobe	carcinoma; adenocarcinoma	Unknown
c.2168G>A; p.G723E; 5:180621007-180621007	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2882G>A; p.R961H; 5:180618889-180618889	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1916G>A; p.S639N; 5:180621646-180621646	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1901C>T; p.A634V; 5:180621661-180621661	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.352G>T; p.A118S; 5:180630603-180630603	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1499C>T; p.P500L; 5:180623984-180623984	skin	malignant_melanoma	Substitution - Missense
c.3531C>G; p.G1177G; 5:180612512-180612512	skin	malignant_melanoma	Substitution - coding silent
c.2091G>T; p.M697I; 5:180621182-180621182	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2181G>T; p.A727A; 5:180620994-180620994	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.2335C>T; p.L779F; 5:180620680-180620680	bone; humerus	chondrosarcoma	Substitution - Missense
c.1638C>T; p.L546L; 5:180622750-180622750	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1895G>A; p.R632H; 5:180621667-180621667	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.3282G>C; p.Q1094H; 5:180614117-180614117	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1638C>T; p.L546L; 5:180622750-180622750	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.859A>G; p.T287A; 5:180629385-180629385	breast	carcinoma	Substitution - Missense
c.2257G>A; p.A753T; 5:180620918-180620918	pancreas	carcinoma	Substitution - Missense
c.1540A>T; p.K514*; 5:180623943-180623943	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Nonsense
c.2940C>T; p.V980V; 5:180618831-180618831	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.655C>A; p.P219T; 5:180629964-180629964	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1082A>C; p.Y361S; 5:180628903-180628903	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1082A>C; p.Y361S; 5:180628903-180628903	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1082A>C; p.Y361S; 5:180628903-180628903	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1082A>C; p.Y361S; 5:180628903-180628903	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.2791A>G; p.K931E; 5:180619080-180619080	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.3148G>A; p.V1050M; 5:180616438-180616438	oesophagus	carcinoma	Substitution - Missense
c.1082A>C; p.Y361S; 5:180628903-180628903	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1082A>C; p.Y361S; 5:180628903-180628903	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1082A>C; p.Y361S; 5:180628903-180628903	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1082A>C; p.Y361S; 5:180628903-180628903	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1082A>C; p.Y361S; 5:180628903-180628903	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1082A>C; p.Y361S; 5:180628903-180628903	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2305G>T; p.E769*; 5:180620710-180620710	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1467G>A; p.W489*; 5:180624016-180624016	skin	malignant_melanoma	Substitution - Nonsense
c.3594C>G; p.S1198R; 5:180611423-180611423	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.488C>T; p.P163L; 5:180630250-180630250	skin	malignant_melanoma	Substitution - Missense
c.1129G>A; p.G377R; 5:180626240-180626240	ovary	other; neoplasm	Substitution - Missense
c.331T>C; p.C111R; 5:180630624-180630624	ovary	carcinoma	Substitution - Missense
c.3119C>T; p.A1040V; 5:180616467-180616467	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1308G>A; p.S436S; 5:180625982-180625982	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1924C>T; p.R642C; 5:180621638-180621638	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.3288C>T; p.D1096D; 5:180614111-180614111	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1308G>A; p.S436S; 5:180625982-180625982	pancreas	carcinoma	Substitution - coding silent
c.1959C>T; p.C653C; 5:180621603-180621603	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1959C>T; p.C653C; 5:180621603-180621603	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.167C>T; p.P56L; 5:180630788-180630788	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2529G>A; p.E843E; 5:180620186-180620186	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.143C>A; p.S48Y; 5:180631694-180631694	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3071G>A; p.G1024E; 5:180616925-180616925	skin	malignant_melanoma	Substitution - Missense
c.1473G>T; p.A491A; 5:180624010-180624010	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.2043G>A; p.T681T; 5:180621230-180621230	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2076C>T; p.S692S; 5:180621197-180621197	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.2076C>T; p.S692S; 5:180621197-180621197	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3179G>A; p.R1060Q; 5:180616407-180616407	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2076C>T; p.S692S; 5:180621197-180621197	autonomic_ganglia	neuroblastoma	Substitution - coding silent
c.2076C>T; p.S692S; 5:180621197-180621197	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.2903G>T; p.R968M; 5:180618868-180618868	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.2431G>A; p.G811S; 5:180620284-180620284	skin	malignant_melanoma	Substitution - Missense
c.1926C>T; p.R642R; 5:180621636-180621636	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.898G>A; p.V300I; 5:180629346-180629346	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.271C>T; p.P91S; 5:180630684-180630684	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1634G>A; p.R545Q; 5:180622754-180622754	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2589C>T; p.S863S; 5:180619723-180619723	central_nervous_system; brain	glioma	Substitution - coding silent
c.1858C>T; p.L620L; 5:180621704-180621704	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.60C>A; p.G20G; 5:180631777-180631777	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.3137C>T; p.S1046L; 5:180616449-180616449	large_intestine; colon	carcinoma	Substitution - Missense
c.3137C>T; p.S1046L; 5:180616449-180616449	skin; ear	malignant_melanoma	Substitution - Missense
c.3137C>T; p.S1046L; 5:180616449-180616449	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1803G>A; p.A601A; 5:180621759-180621759	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1803G>A; p.A601A; 5:180621759-180621759	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1382G>A; p.R461Q; 5:180625908-180625908	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1335C>G; p.C445W; 5:180625955-180625955	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1765C>T; p.R589C; 5:180621797-180621797	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.480G>A; p.V160V; 5:180630258-180630258	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3537+1G>T; p.?; 5:180612505-180612505	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Unknown
c.1911C>G; p.S637R; 5:180621651-180621651	stomach	carcinoma	Substitution - Missense
c.211G>A; p.G71R; 5:180630744-180630744	skin; trunk	malignant_melanoma; nodular	Substitution - Missense
c.211G>A; p.G71R; 5:180630744-180630744	skin	malignant_melanoma	Substitution - Missense
c.1711G>A; p.G571S; 5:180621851-180621851	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2336T>G; p.L779R; 5:180620679-180620679	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1931C>T; p.A644V; 5:180621631-180621631	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2584G>A; p.A862T; 5:180619728-180619728	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2217C>T; p.R739R; 5:180620958-180620958	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2217C>T; p.R739R; 5:180620958-180620958	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1523C>T; p.T508I; 5:180623960-180623960	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.3731C>T; p.A1244V; 5:180609981-180609981	skin	malignant_melanoma	Substitution - Missense
c.1893G>A; p.A631A; 5:180621669-180621669	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.3731C>T; p.A1244V; 5:180609981-180609981	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1893G>A; p.A631A; 5:180621669-180621669	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.3601C>T; p.Q1201*; 5:180611416-180611416	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1480A>G; p.T494A; 5:180624003-180624003	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.951G>A; p.Q317Q; 5:180629293-180629293	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3576G>C; p.Q1192H; 5:180611441-180611441	central_nervous_system; brain	glioma; astrocytoma_Grade_III	Substitution - Missense
c.519C>A; p.S173R; 5:180630100-180630100	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.519C>A; p.S173R; 5:180630100-180630100	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.519C>A; p.S173R; 5:180630100-180630100	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3210C>T; p.R1070R; 5:180616376-180616376	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.3092G>T; p.R1031L; 5:180616904-180616904	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.3709C>T; p.P1237S; 5:180610003-180610003	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2004G>A; p.K668K; 5:180621558-180621558	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.360C>T; p.I120I; 5:180630595-180630595	skin	malignant_melanoma	Substitution - coding silent
c.784G>A; p.V262I; 5:180629728-180629728	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.165C>T; p.H55H; 5:180630790-180630790	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.185C>T; p.P62L; 5:180630770-180630770	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.58+9G>A; p.?; 5:180649479-180649479	liver	carcinoma	Unknown
c.2496C>A; p.S832S; 5:180620219-180620219	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.58+9G>A; p.?; 5:180649479-180649479	liver	carcinoma	Unknown
c.1426C>T; p.R476W; 5:180624057-180624057	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.503C>T; p.T168M; 5:180630235-180630235	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2281G>A; p.A761T; 5:180620894-180620894	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.503C>T; p.T168M; 5:180630235-180630235	pancreas	carcinoma	Substitution - Missense
c.991C>T; p.P331S; 5:180628994-180628994	skin	malignant_melanoma	Substitution - Missense
c.1426C>T; p.R476W; 5:180624057-180624057	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2997A>G; p.Q999Q; 5:180618774-180618774	breast	carcinoma	Substitution - coding silent
c.1662C>T; p.I554I; 5:180621900-180621900	skin	malignant_melanoma	Substitution - coding silent
c.3410C>T; p.P1137L; 5:180613032-180613032	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3410C>T; p.P1137L; 5:180613032-180613032	skin	malignant_melanoma	Substitution - Missense
c.450G>A; p.R150R; 5:180630288-180630288	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1422-1G>A; p.?; 5:180624062-180624062	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.2114delA; p.H705fs*29; 5:180621159-180621159	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3144C>T; p.S1048S; 5:180616442-180616442	pancreas	carcinoma	Substitution - coding silent
c.279C>A; p.C93*; 5:180630676-180630676	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.157G>A; p.G53R; 5:180630798-180630798	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1228C>T; p.R410C; 5:180626141-180626141	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2056G>A; p.D686N; 5:180621217-180621217	skin	malignant_melanoma	Substitution - Missense
c.3681C>T; p.A1227A; 5:180611336-180611336	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.3681C>T; p.A1227A; 5:180611336-180611336	breast	carcinoma	Substitution - coding silent
c.1833G>A; p.K611K; 5:180621729-180621729	thyroid	carcinoma	Substitution - coding silent
c.851C>T; p.S284F; 5:180629393-180629393	skin	malignant_melanoma	Substitution - Missense
c.3209G>A; p.R1070H; 5:180616377-180616377	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.3123G>A; p.R1041R; 5:180616463-180616463	skin	malignant_melanoma	Substitution - coding silent
c.1472C>T; p.A491V; 5:180624011-180624011	skin	malignant_melanoma	Substitution - Missense
c.3167T>G; p.F1056C; 5:180616419-180616419	skin	malignant_melanoma	Substitution - Missense
c.2127_2128CG>TT; p.V710L; 5:180621145-180621146	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1261C>T; p.P421S; 5:180626029-180626029	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1261C>T; p.P421S; 5:180626029-180626029	skin	malignant_melanoma	Substitution - Missense
c.2652C>T; p.G884G; 5:180619362-180619362	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2670C>G; p.H890Q; 5:180619344-180619344	breast	carcinoma	Substitution - Missense
c.2670C>G; p.H890Q; 5:180619344-180619344	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2670C>G; p.H890Q; 5:180619344-180619344	thyroid	other; neoplasm	Substitution - Missense
c.1296delC; p.S433fs*60; 5:180625994-180625994	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2532G>A; p.R844R; 5:180620183-180620183	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.60C>G; p.G20G; 5:180631777-180631777	skin	malignant_melanoma	Substitution - coding silent
c.1500C>G; p.P500P; 5:180623983-180623983	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1500C>G; p.P500P; 5:180623983-180623983	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.3209G>T; p.R1070L; 5:180616377-180616377	skin	malignant_melanoma	Substitution - Missense
c.94T>A; p.L32M; 5:180631743-180631743	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.3209G>T; p.R1070L; 5:180616377-180616377	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3121C>T; p.R1041W; 5:180616465-180616465	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1936G>A; p.E646K; 5:180621626-180621626	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2117C>A; p.A706E; 5:180621156-180621156	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.168_183del16; p.L57fs*71; 5:180630772-180630787	prostate	carcinoma	Deletion - Frameshift
c.3181G>A; p.D1061N; 5:180616405-180616405	skin	malignant_melanoma	Substitution - Missense
c.1092C>T; p.P364P; 5:180628893-180628893	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2671C>T; p.R891C; 5:180619343-180619343	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1737A>G; p.Q579Q; 5:180621825-180621825	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.892C>A; p.H298N; 5:180629352-180629352	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3877C>G; p.Q1293E; 5:180608984-180608984	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.3773T>A; p.F1258Y; 5:180609939-180609939	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.478G>T; p.V160L; 5:180630260-180630260	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.507G>T; p.L169L; 5:180630231-180630231	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.947T>C; p.I316T; 5:180629297-180629297	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.118G>C; p.V40L; 5:180631719-180631719	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.645C>T; p.F215F; 5:180629974-180629974	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.428C>A; p.P143H; 5:180630310-180630310	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.428C>A; p.P143H; 5:180630310-180630310	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2643delG; p.E883fs*11; 5:180619669-180619669	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.645C>T; p.F215F; 5:180629974-180629974	skin	malignant_melanoma	Substitution - coding silent
c.1736A>G; p.Q579R; 5:180621826-180621826	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3867C>G; p.S1289R; 5:180608994-180608994	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3201C>A; p.D1067E; 5:180616385-180616385	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.356G>A; p.R119H; 5:180630599-180630599	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1464C>A; p.D488E; 5:180624019-180624019	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2675C>T; p.A892V; 5:180619339-180619339	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2499C>T; p.Y833Y; 5:180620216-180620216	soft_tissue; striated_muscle	rhabdomyosarcoma	Substitution - coding silent
c.2872G>T; p.G958*; 5:180618899-180618899	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3634G>A; p.A1212T; 5:180611383-180611383	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2499C>T; p.Y833Y; 5:180620216-180620216	soft_tissue; striated_muscle	rhabdomyosarcoma; alveolar	Substitution - coding silent
c.3289G>A; p.V1097M; 5:180614110-180614110	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.1822C>T; p.L608F; 5:180621740-180621740	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3289G>A; p.V1097M; 5:180614110-180614110	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3746C>T; p.S1249F; 5:180609966-180609966	skin	malignant_melanoma	Substitution - Missense
c.240G>T; p.V80V; 5:180630715-180630715	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3746C>T; p.S1249F; 5:180609966-180609966	breast	carcinoma	Substitution - Missense
c.1929C>T; p.V643V; 5:180621633-180621633	skin; abdomen	malignant_melanoma	Substitution - coding silent
c.1370A>G; p.Q457R; 5:180625920-180625920	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.531G>A; p.W177*; 5:180630088-180630088	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3865A>G; p.S1289G; 5:180608996-180608996	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3865A>G; p.S1289G; 5:180608996-180608996	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2287G>A; p.V763M; 5:180620888-180620888	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1421+1G>A; p.?; 5:180625868-180625868	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1500C>T; p.P500P; 5:180623983-180623983	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1110G>T; p.K370N; 5:180626259-180626259	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3504C>T; p.I1168I; 5:180612539-180612539	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1132C>T; p.R378C; 5:180626237-180626237	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1132C>T; p.R378C; 5:180626237-180626237	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2616C>A; p.S872R; 5:180619696-180619696	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2116G>A; p.A706T; 5:180621157-180621157	thyroid	carcinoma	Substitution - Missense
c.2328C>T; p.I776I; 5:180620687-180620687	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2328C>T; p.I776I; 5:180620687-180620687	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.3668G>A; p.R1223H; 5:180611349-180611349	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3122G>A; p.R1041Q; 5:180616464-180616464	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1319G>A; p.R440H; 5:180625971-180625971	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3068G>A; p.R1023K; 5:180616928-180616928	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1423C>T; p.R475W; 5:180624060-180624060	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1066G>T; p.V356L; 5:180628919-180628919	kidney	other; neoplasm	Substitution - Missense
c.445A>G; p.N149D; 5:180630293-180630293	thyroid	other; neoplasm	Substitution - Missense
c.779C>G; p.S260*; 5:180629733-180629733	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.3718C>T; p.L1240L; 5:180609994-180609994	liver	carcinoma	Substitution - coding silent
c.3718C>T; p.L1240L; 5:180609994-180609994	liver	carcinoma	Substitution - coding silent
c.3459C>T; p.S1153S; 5:180612584-180612584	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.312C>T; p.N104N; 5:180630643-180630643	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1027C>T; p.L343L; 5:180628958-180628958	skin	malignant_melanoma	Substitution - coding silent
c.265G>A; p.A89T; 5:180630690-180630690	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.886A>C; p.T296P; 5:180629358-180629358	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1655C>A; p.T552N; 5:180622733-180622733	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2350G>A; p.V784I; 5:180620665-180620665	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3628G>A; p.A1210T; 5:180611389-180611389	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3399G>A; p.R1133R; 5:180613043-180613043	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.598G>A; p.D200N; 5:180630021-180630021	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.598G>A; p.D200N; 5:180630021-180630021	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2710G>A; p.G904S; 5:180619304-180619304	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3391G>A; p.G1131S; 5:180613051-180613051	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.539G>T; p.G180V; 5:180630080-180630080	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.3261C>T; p.F1087F; 5:180614138-180614138	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1433A>G; p.Q478R; 5:180624050-180624050	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1169_1170CA>AG; p.T390K; 5:180626199-180626200	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.503C>G; p.T168R; 5:180630235-180630235	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1941C>T; p.H647H; 5:180621621-180621621	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.1941C>T; p.H647H; 5:180621621-180621621	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1504G>A; p.E502K; 5:180623979-180623979	skin	malignant_melanoma	Substitution - Missense
c.2416G>T; p.A806S; 5:180620299-180620299	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1636C>T; p.L546F; 5:180622752-180622752	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.893A>G; p.H298R; 5:180629351-180629351	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3262G>A; p.D1088N; 5:180614137-180614137	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.847C>T; p.R283C; 5:180629397-180629397	urinary_tract; bladder	carcinoma	Substitution - Missense
c.888C>T; p.T296T; 5:180629356-180629356	skin	malignant_melanoma	Substitution - coding silent
c.3029C>T; p.T1010I; 5:180616967-180616967	skin	malignant_melanoma	Substitution - Missense
c.3029C>T; p.T1010I; 5:180616967-180616967	skin	malignant_melanoma	Substitution - Missense
c.191C>A; p.A64D; 5:180630764-180630764	pancreas	carcinoid-endocrine_tumour	Substitution - Missense
c.847C>T; p.R283C; 5:180629397-180629397	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3262G>A; p.D1088N; 5:180614137-180614137	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2568C>T; p.F856F; 5:180619744-180619744	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1960G>A; p.E654K; 5:180621602-180621602	skin	malignant_melanoma	Substitution - Missense
c.2036G>A; p.R679Q; 5:180621237-180621237	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.327C>T; p.Y109Y; 5:180630628-180630628	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3712_3713GG>TT; p.G1238L; 5:180609999-180610000	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1617G>A; p.K539K; 5:180622771-180622771	skin	malignant_melanoma	Substitution - coding silent
c.2721C>T; p.L907L; 5:180619293-180619293	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1549-1G>A; p.?; 5:180622840-180622840	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.3037G>T; p.D1013Y; 5:180616959-180616959	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3037G>T; p.D1013Y; 5:180616959-180616959	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3525C>T; p.G1175G; 5:180612518-180612518	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1694C>T; p.S565F; 5:180621868-180621868	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1668C>T; p.D556D; 5:180621894-180621894	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1668C>T; p.D556D; 5:180621894-180621894	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3375C>T; p.C1125C; 5:180613067-180613067	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.660C>T; p.F220F; 5:180629959-180629959	skin	malignant_melanoma	Substitution - coding silent
c.434C>T; p.T145M; 5:180630304-180630304	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3214G>A; p.G1072S; 5:180616372-180616372	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2424C>T; p.I808I; 5:180620291-180620291	skin	malignant_melanoma	Substitution - coding silent
c.3864G>A; p.E1288E; 5:180608997-180608997	autonomic_ganglia	neuroblastoma	Substitution - coding silent
c.3268G>A; p.V1090M; 5:180614131-180614131	skin	malignant_melanoma	Substitution - Missense
c.2143G>A; p.E715K; 5:180621130-180621130	skin	malignant_melanoma	Substitution - Missense
c.1472C>A; p.A491E; 5:180624011-180624011	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2965G>C; p.E989Q; 5:180618806-180618806	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1173G>T; p.E391D; 5:180626196-180626196	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2407-2A>T; p.?; 5:180620310-180620310	liver	carcinoma; hepatocellular_carcinoma	Unknown
c.1097T>C; p.F366S; 5:180628888-180628888	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1762C>A; p.L588M; 5:180621800-180621800	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2602C>T; p.H868Y; 5:180619710-180619710	kidney	other; neoplasm	Substitution - Missense
c.3722C>A; p.A1241D; 5:180609990-180609990	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2407-2A>T; p.?; 5:180620310-180620310	liver	carcinoma; hepatocellular_carcinoma	Unknown
c.1554G>A; p.V518V; 5:180622834-180622834	breast	carcinoma	Substitution - coding silent
c.2083C>T; p.L695L; 5:180621190-180621190	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2770A>G; p.M924V; 5:180619101-180619101	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.829A>C; p.K277Q; 5:180629415-180629415	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3432A>G; p.I1144M; 5:180612611-180612611	skin	malignant_melanoma	Substitution - Missense
c.3489G>A; p.S1163S; 5:180612554-180612554	pancreas	carcinoma	Substitution - coding silent
c.885G>A; p.L295L; 5:180629359-180629359	breast	carcinoma	Substitution - coding silent
c.632G>A; p.G211E; 5:180629987-180629987	skin	malignant_melanoma	Substitution - Missense
c.2268C>T; p.C756C; 5:180620907-180620907	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3341C>T; p.P1114L; 5:180613101-180613101	kidney	other; neoplasm	Substitution - Missense
c.2437C>A; p.L813M; 5:180620278-180620278	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2118G>A; p.A706A; 5:180621155-180621155	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2485G>A; p.E829K; 5:180620230-180620230	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3780G>A; p.M1260I; 5:180609932-180609932	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2485G>A; p.E829K; 5:180620230-180620230	skin	malignant_melanoma	Substitution - Missense
c.875C>T; p.S292F; 5:180629369-180629369	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3661C>T; p.L1221L; 5:180611356-180611356	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1197C>T; p.L399L; 5:180626172-180626172	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.394G>A; p.V132M; 5:180630561-180630561	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2514G>T; p.W838C; 5:180620201-180620201	pancreas	carcinoma	Substitution - Missense
c.244C>T; p.R82*; 5:180630711-180630711	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2673C>T; p.R891R; 5:180619341-180619341	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.963G>C; p.E321D; 5:180629281-180629281	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.948C>T; p.I316I; 5:180629296-180629296	skin	malignant_melanoma	Substitution - coding silent
c.2211C>T; p.R737R; 5:180620964-180620964	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1106A>T; p.Y369F; 5:180626263-180626263	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.89C>T; p.P30L; 5:180631748-180631748	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3799G>T; p.G1267C; 5:180609913-180609913	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1658-1G>C; p.?; 5:180621905-180621905	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Unknown
c.3688T>C; p.Y1230H; 5:180610024-180610024	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.566G>C; p.R189P; 5:180630053-180630053	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1267delC; p.Q423fs*70; 5:180626023-180626023	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1267delC; p.Q423fs*70; 5:180626023-180626023	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3147C>T; p.D1049D; 5:180616439-180616439	pancreas	carcinoma	Substitution - coding silent
c.3178C>T; p.R1060W; 5:180616408-180616408	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1267delC; p.Q423fs*70; 5:180626023-180626023	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1350G>T; p.V450V; 5:180625940-180625940	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.985G>A; p.E329K; 5:180629259-180629259	skin	malignant_melanoma	Substitution - Missense
c.3437G>A; p.R1146H; 5:180612606-180612606	thyroid	other; neoplasm	Substitution - Missense
c.1534G>A; p.E512K; 5:180623949-180623949	skin	malignant_melanoma	Substitution - Missense
c.313G>A; p.D105N; 5:180630642-180630642	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.504G>A; p.T168T; 5:180630234-180630234	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3091C>T; p.R1031*; 5:180616905-180616905	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.313G>A; p.D105N; 5:180630642-180630642	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3091C>T; p.R1031*; 5:180616905-180616905	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3271T>C; p.Y1091H; 5:180614128-180614128	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1326C>T; p.A442A; 5:180625964-180625964	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3271T>C; p.Y1091H; 5:180614128-180614128	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2416G>A; p.A806T; 5:180620299-180620299	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.89_90insC; p.T31fs*15; 5:180631747-180631748	large_intestine; rectum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1741G>A; p.D581N; 5:180621821-180621821	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.89_90insC; p.T31fs*15; 5:180631747-180631748	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1101G>A; p.Q367Q; 5:180628884-180628884	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1107C>A; p.Y369*; 5:180626262-180626262	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.3072G>A; p.G1024G; 5:180616924-180616924	skin	malignant_melanoma	Substitution - coding silent
c.1741G>A; p.D581N; 5:180621821-180621821	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1101G>A; p.Q367Q; 5:180628884-180628884	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.3076G>A; p.E1026K; 5:180616920-180616920	skin	malignant_melanoma	Substitution - Missense
c.1797C>T; p.H599H; 5:180621765-180621765	breast	carcinoma	Substitution - coding silent
c.3204C>T; p.Y1068Y; 5:180616382-180616382	central_nervous_system; brain	glioma	Substitution - coding silent
c.3204C>T; p.Y1068Y; 5:180616382-180616382	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2883C>T; p.R961R; 5:180618888-180618888	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1904C>T; p.T635M; 5:180621658-180621658	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3063G>A; p.V1021V; 5:180616933-180616933	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2304C>T; p.S768S; 5:180620711-180620711	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.75C>A; p.Y25*; 5:180631762-180631762	pancreas	carcinoma	Substitution - Nonsense
c.3743G>T; p.G1248V; 5:180609969-180609969	lung	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation