lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

2237

PubMed (Gene Name)

Literature evidence

14562054 (FEN1)

Alterations of FEN1 are not likely to contribute to development of lung cancer.

19618370 (FEN1)

These results highlight FEN1 as an important gene in human carcinogenesis and genetic polymorphisms in FEN1 confer susceptibility to lung cancer.

28371273 (FEN1)

FEN1 is essential for prolifera- tion and cisplatin resistance of lung cancer cells.

29037854 (FEN1)

Notably, non-small cell lung cancer patients with FEN1-overexpressed cancers were prone to have poor differentiation and poor prognosis. Furthermore, knockdown of FEN1 resulted in G1/S or G2/M phase cell cycle arrest and suppressed in vitro cellular proliferation in NSCLC cancer cells.

32861926 (FEN1)

PRMT1 is critical to FEN1 expression and drug resistance in lung cancer cells.