Links to all GeneRIF Items | 2185 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 17906699 (PTK2B) | Proline-rich tyrosine kinase Pyk2 is highly expressed in small cell lung cancer cells and provides a functional link between neuropeptide-induced increases in intracellular calcium ions [Ca2+]i, and tumor cell proliferation. |
| 18571765 (PTK2B) | Up-regulation of proline-rich tyrosine kinase 2 is associated with non-small cell lung cancer. |
| 22581436 (PTK2B) | PAC1 regulates PYK-2 tyrosine phosphorylation in a calcium-dependent manner in lung cancer cell lines. |
| 23922106 (PTK2B) | Both Pyk2 and phosphorylated Pyk2[pY881] are potential prognostic factors and therapeutic targets for non-small-cell lung cancer. |