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Cancer metastasis database

Annotation category 5

Expression and regulation

Regulation From TransFac database

Pyk2-isoform1(h) + paxillin(h) <==> Pyk2-isoform1(h):paxillin(h) (binding)
Grb-2(h) + Pyk2-isoform1(h) <==> Grb-2(h):Pyk2-isoform1(h) (binding)
Pyk2-isoform1(h) + Hic-5(h) <==> Pyk2-isoform1(h):Hic-5(h) (binding)
Pyk2-isoform1(h) + ATP --> Pyk2-isoform1(h){p} + ADP (phosphorylation)
Cas(h) + Pyk2-isoform1(h) <==> Pyk2-isoform1(h):Cas(h) (binding)
Pyk2-isoform1(h) + leupaxin(h) <==> Pyk2-isoform1(h):leupaxin(h) (binding)
Pyk2-isoform1(h) + Graf2(h) <==> Pyk2-isoform1(h):Graf2(h) (binding)
Pyk2-isoform1(h) + DDEF2alpha(h) <==> Pyk2-isoform1(h):DDEF2alpha(h) (binding)
Pyk2-isoform1(h) + DDEF2beta(m) <==> Pyk2-isoform1(h):DDEF2beta(m) (binding)
ErbB1(h) + Pyk2-isoform1(h) <==> ErbB1(h):Pyk2-isoform1(h) (binding)
Src(h) + Pyk2-isoform1(h) <==> Src(h):Pyk2-isoform1(h) (binding)
Pyk2-isoform1(h) + STAT3(h) <==> Pyk2-isoform1(h):STAT3(h) (binding)
Pyk2-isoform1(h) + ATP --> Pyk2-isoform1(h){pY881} + ADP (phosphorylation)
PSD-95alpha(r) + Pyk2-isoform1(h) <==> PSD-95alpha(r):Pyk2-isoform1(h) (binding)
SAP102(r) + Pyk2-isoform1(h) <==> SAP102(r):Pyk2-isoform1(h) (binding)
PTK2B(h) --> Pyk2-isoform1(h) (expression).
Pyk2-isoform1(h):Hic-5(h) + NTP --> Pyk2-isoform1(h) + Hic-5(h){p} + NDP (phosphorylation; dissociation)
beta1-integrin(h) --> Pyk2-isoform1(h) (activation; phosphorylation)
BCR(h) --> Pyk2-isoform1(h) (activation; phosphorylation)
RANTES(h) --> Pyk2-isoform2(h) (activation; phosphorylation)
MIP1B(h) --> Pyk2-isoform2(h) (activation; phosphorylation)
PTK2B(h) --> Pyk2-isoform2(h) (expression).
Alix(m.s.) + Pyk2(h) <==> Alix(m.s.):Pyk2(h) (binding)
Pyk2(h) + 2 ATP --> Pyk2(h){pY402}{pY881} + 2 ADP (phosphorylation)
Pyk2(h) --> Prap(h){pY} (increase of phosphorylation)
Prap(h) + Pyk2(h) <==> Prap(h):Pyk2(h) (binding)
Pyk2(h) --> NACP(h){pY} (increase of phosphorylation)
Pyk2(h) --> Src(h){pY} (increase of phosphorylation)
Hic-5(m.s.) + Pyk2(h) <==> Hic-5(m.s.):Pyk2(h) (binding)
SHP-1(h) + Pyk2(h) <==> SHP-1(h):Pyk2(h) (binding)
MEKK4(h) + Pyk2(h) <==> MEKK4(h):Pyk2(h) (binding)
Pyk2(h) + ATP --> Pyk2(h){pY} + ADP (phosphorylation)
HEF1(h) + Pyk2(h) <==> HEF1(h):Pyk2(h) (binding)
Cas(h) + Pyk2(h) <==> Cas(h):Pyk2(h) (binding)
ErbB1(h) + Pyk2(h) <==> ErbB1(h):Pyk2(h) (binding)
Pyk2(h) + Src(h) <==> Pyk2(h):Src(h) (binding)
Pyk2(h) + p190RhoGAP(h) <==> Pyk2(h):p190RhoGAP(h) (binding)
Pyk2(h) + RasGAP(h) <==> Pyk2(h):RasGAP(h) (binding)
Pyk2(h) + p190RhoGAP(r) <==> Pyk2(h):p190RhoGAP(r) (binding)
Pyk2(h) + ErbB2(h) <==> Pyk2(h):ErbB2(h) (binding)
Pyk2(h) + ATP --> Pyk2(h){pY881} + ADP (phosphorylation)
PTK2B(h) --> Pyk2(h) (expression).
Pyk2(h){pY} --SHP-2(h)--> p + Pyk2(h) (dephosphorylation)
MEKK4(h) + ATP --Pyk2(h)--> MEKK4(h){pY} + ADP (phosphorylation)

Human Primary Tumor Samples (U95)  | Top

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Human U133A/GNF1H Gene Atlas  | Top