lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

2150

PubMed (Gene Name)

Literature evidence

24138209 (F2RL1)

Activation of PAR2 by tryptase can decrease the ratio of Bax/Bcl-xL in A549 lung cancer cells, preventing apoptosis.

24643912 (F2RL1)

KLK6 promotes the proliferation of lung tumoral cells and restrains their apoptosis in vitro via ligand-dependent EGFR and was dependent on the protease-activated receptor 2.

27924164 (F2RL1)

Study demonstrates that AHRR and F2RL3 methylation are strong predictors individually for lung cancer development.