lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

1728

PubMed (Gene Name)

Literature evidence

12163326 (NQO1)

NQO1-Pro/Pro genotype is a risk factor for lung adenocarcinoma development

14592434 (NQO1)

These results provide the first evidence of a proximal repressor region exerting a negative role on the regulation of the hNQO1 promoter in small cell lung carcinoma.

15498787 (NQO1)

The observed risk reductions of lung cancer may be attributable to the greatly reduced procarcinogen activating of NAD(P)H:quinone oxidoreductase 1 in individuals with at least one copy of the T allele.

18798003 (NQO1)

genetic polymorphisms for NQO1, CYP2E1, and ALDH2 synergistically with cumulative smoking amounts and alcohol drinking levels interact in the carcinogenesis of lung cancer in Koreans.

19596483 (NQO1)

genetic polymorphisms affects treatment outcome after postoperative radiation therapy in completely resected non-small cell lung cancer

20091863 (NQO1)

Modifying effect of NQO1 polymorphisms on the risk of early-onset lung cancer.

21479364 (NQO1)

NQO1*2/*2 may be an independent predictor of poor overall survival in individuals with resected stages II and IIIa non-small cell lung cancer

21964527 (NQO1)

C609T polymorphism of NAD(P)H quinone oxidoreductase 1 is associated with response to amrubicin therapy in lung cancer.

22393995 (NQO1)

meta-analysis suggests that the variant NQO1 C609T genotype may affect individual susceptibility to lung cancer; this meta-analysis suggests that the NQO1 609T allele is a low penetrant risk factor for developing lung cancer in Chinese

23110137 (NQO1)

No association between NADPH quinone oxidoreductase 1 (NQO1) gene C609T polymorphism and lung cancer in a Chinese case-control study and a larger meta-analysis.

23852860 (NQO1)

Studies suggest that NAD(P)H: quinone oxidoreductase 1 (NQO1) C609T polymorphism might associate with lung cancer risk in Caucasians.

25222473 (NQO1)

NQO1 expression was significantly more frequent in non-small cell lung carcinoma patients with KRAS mutations, suggesting that oxidative stress may be important in the pathogenesis, worse prognosis, and resistance to treatment reported in these patients.

25231218 (NQO1)

NQO1 plays an important role in the progression of small cell lung cancer.

25400754 (NQO1)

NQO1 genetic polymorphisms were not associated with prognosis in limited-stage small cell lung cancer.

25729241 (NQO1)

The results suggests that haplotypes of the NQO1 gene play an important role in the development of lung cancer by interaction with smoking.

25880877 (NQO1)

NQO1 is upregulated in NSCLC, and it may be a useful poor prognostic biomarker and a potential therapeutic target for patients with non-small cell lung cancer

26452990 (NQO1)

Flavin reductase and calreticulin play key roles in the development of pemetrexed-associated resistance in lung adenocarcinoma cells.