lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

1655

PubMed (Gene Name)

Literature evidence

26212035 (DDX5)

DDX5 played an important role in the proliferation and tumorigenesis of non-small-cell lung cancer cells by activating the beta-catenin signaling pathway.

30720177 (DDX5)

miR-431 expression was significantly lower in lung cancer (LCa) tissue samples or cell lines compared to adjacent normal tissues or lung bronchial epithelial cell line, respectively. Overexpression of miR-431 significantly inhibited proliferation, invasion and migration of A549 cells. Downregulation of miR-431 accelerated cell growth and metastasis of H1650 cells. DDX5 was proved to be a direct target for miR-431 in LCa.