Links to all GeneRIF Items | 1647 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 16827157 (GADD45A) | The overall median mRNA expression level of Gadd45 was approximately 10-fold lower in tumor tissues than in matching normal lung tissues. High intratumoral Gadd45 expression was significantly associated with a poorer histological grading. |
| 20652500 (GADD45A) | Finding suggests that methylation-associated down-regulation of the GADD45G gene may be involved in lung tumorigenesis. |
| 26993769 (GADD45A) | present study provides evidence that variations in GADD45B rs2024144T, MAPK14 rs3804451A and GADD45A rs581000C may predict platinum-based chemotherapy toxicity outcomes in patients with advanced non-small cell lung cancer |
| 16141330 (Gadd45a) | Deletion of Gadd45a alone does not lead to increased lung tumors in mice, but coupled with an XPC deletion, it results in lung tumor progression |