Cancer metastasis database

Annotation category 5

Gene information

Gene ID 1647
Symbol

GADD45A

Synonymous

DDIT1|GADD45

Full name

growth arrest and DNA-damage-inducible, alpha

Gene description

DDIT-1|DNA damage-inducible transcript 1 protein|DNA damage-inducible transcript-1|DNA-damage-inducible transcript 1|growth arrest and DNA damage-inducible protein GADD45 alpha|growth arrest and DNA-damage-inducible 45 alpha

Cytoband

1p31.2

Gene type

protein-coding

Synonymous

MIM:126335; HGNC:HGNC:4095; Ensembl:ENSG00000116717; HPRD:00528; Vega:OTTHUMG00000009374

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.344G>T; p.G115V; 1:67686547-67686547

lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.473C>T; p.P158L; 1:67687749-67687749

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.299A>G; p.E100G; 1:67686502-67686502

ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.418T>C; p.L140L; 1:67687694-67687694

large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.72G>T; p.E24D; 1:67686052-67686052

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.71A>T; p.E24V; 1:67686051-67686051

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.451C>T; p.R151C; 1:67687727-67687727

skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.115G>C; p.G39R; 1:67686095-67686095

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.453C>T; p.R151R; 1:67687729-67687729

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.209C>T; p.A70V; 1:67686412-67686412

adrenal_gland; adrenal_glandadrenal_cortical_carcinoma; functioningSubstitution - Missense

c.391C>T; p.H131Y; 1:67687667-67687667

large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.389_390delCA; p.H131fs*30; 1:67687665-67687666

ovarycarcinoma; clear_cell_carcinomaDeletion - Frameshift

c.236A>G; p.Q79R; 1:67686439-67686439

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.349G>A; p.E117K; 1:67686552-67686552

urinary_tract; bladdercarcinomaSubstitution - Missense