Links to all GeneRIF Items | 1571 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 12198369 (CYP2E1) | In the CYP2E1 gene 5'-flanking region polymorphism, patients with esophageal cancer showed significantly higher frequency of the A4/A4 genotype compared with the control subjects (p = 0.02), but no difference was found in patients with lung cancer. |
| 16142352 (CYP2E1) | the A4/A4 genotype of the 5'-flanking region of CYP2E1 has a role in development of non-small cell lung carcinoma in Japanese patients |
| 16311924 (CYP2E1) | We report here for the first time three novel alternative spliced mRNA transcripts which are more frequently present in lung carcinoma cell lines as in hepatocyte cell lines. |
| 17559142 (CYP2E1) | examined genetic polymorphisms in the alcohol dehydrogenase 3, aldehyde dehydrogenase 2, and cytochrome P450 2E1 genes in 505 patients with histologically confirmed lung cancer and 256 noncancer controls to determine association with alcohol drinking |
| 18798003 (CYP2E1) | genetic polymorphisms for NQO1, CYP2E1, and ALDH2 synergistically with cumulative smoking amounts and alcohol drinking levels interact in the carcinogenesis of lung cancer in Koreans. |
| 19796841 (CYP2E1) | gene polymorphism is associated with lung cancer risk among Asians |
| 20031389 (CYP2E1) | The meta-analysis suggests that CYP2E1 RsaI/PstI and DraI polymorphisms may affect the susceptibility of lung cancer |
| 22761909 (CYP2E1) | a potentially synergistic association of PTGS2 and CYP2E1 polymorphisms with the underlying cause of lung cancer in northeastern Chinese |
| 23934444 (CYP2E1) | CYP2E1 -1239G>C polymorphism was associated with a lower risk of NSCLC and that a potential protective effect of this polymorphism was modified by smoking status, which suggested that CYP2E1 played an important role in the development of lung cancer. |
| 25336053 (CYP2E1) | CYP2E1 polymorphisms are associated with lung cancer risk. [Meta-analysis] |
| 25422202 (CYP2E1) | We found that c1/c1, DD, and slow acetylation of CYP2E1 Rsa I/Pst I, Dra I and N-acetyltransferase 2 Wt/Mx polymorphisms contributes to the development of lung cancer, especially when c1/c1 and slow acetylation take a combination of act. |
| 27644662 (CYP2E1) | CYP2E1 rs2031920 and COMT rs4680 are not major contributors to lung cancer risk. |
| 28033105 (CYP2E1) | A significant increase in the risk of non-small cell lung cancer was observed for the following combinations: TP53 codon72 variant with GSTM1 null (OR 2.22, 95 % CI 1.23-4.04; p=0.009), GSTT1 null (OR 2.98, 95 % CI 1.49-5.94; p=0.002), and GSTP1 (Ala114Val) variant genotypes (OR 3.38, 95 % CI 1.54-7.41; p=0.002). |