Beta-2 adrenergic receptor gene polymorphism is associated with lung adenocarcinoma

beta2-adrenergic receptor can serve as a significant predictor of tumor aggressiveness and poor survival for pulmonary pleomorphic carcinoma patients, especially those with early-stage disease.

the data obtained in this study suggest that EHD1 plays a critical role in Non-small cell lung cancer (NSCLC) angiogenesis via b2AR signaling and highlight a potential target for antiangiogenic therapy.

Beta1- and Beta2-Adrenoceptors expression Patterns in Human Non-small Cell lung cancer: Relationship with cancer Histology.

In a Chinese Han population, we identified ADRB2 polymorphisms (rs1042711 and rs1560642) that were associated with increased risk of lung cancer, and polymorphisms in IL33 (rs7025417) and IL2RB (rs5756523 and rs2284033) that were associated with decreased disease risk.