lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

1524

PubMed (Gene Name)

Literature evidence

20439195 (CX3CR1)

We studied a unique cohort of 21 primary lung cancers with matched adrenal metastases for the expression of CX3CR1, CXCR4, CCR6, and CCR7

21278339 (CX3CR1)

Use of cx3cr1 transgenic mice in a pulmonary emphysema model demonstrates requirement of functional CX3CR1 for a subset of tissue-bound mononuclear phagocytes to produce tumor necrosis factor (TNF)-alpha and interleukin (IL)-6 in response to cigarette smoke.

22614623 (CX3CR1)

CX3CR1 is upregulated in NSCLC metastatic disease and its expression in primary lung tumours relates inversely to organotropic spread of cancer cells to the brain and the liver.