Links to all GeneRIF Items | 1452 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 25628462 (Csnk1a1) | Phosphorylation of FADD by the kinase CK1alpha promotes KRASG12D-induced lung cancer. |
| 26984280 (CSNK1A1) | NIFK is required for lung cancer progression via the RUNX1-dependent CK1alpha repression, which activates TCF4/beta-catenin signaling in metastasis and the Ki-67-dependent regulation in cell proliferation. |
| 29593330 (CSNK1A1) | CK1alpha bound the C-terminal tail of PTEN and enhanced both PTEN stability and activity by competitively antagonizing NEDD4-1-induced PTEN polyubiquitination and abrogating PTEN phosphorylation, thereby inhibiting AKT activity and activating FOXO3a-induced transcription of Atg7, to suppress lung tumor growth. |