Links to all GeneRIF Items | 10401 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 15138572 (PIAS3) | Increased PIAS3 expression is associated with human cancers including lung, breast, prostate, colon-rectum, and brain tumors |
| 17032498 (PIAS3) | overexpression of PIAS3 in lung cancer cells contributed to growth suppression and restored the drug sensitivity of the cells |
| 21497567 (PIAS3) | Squamous cell carcinoma of the lung commonly lacks PIAS3 protein expression. |
| 23959540 (PIAS3) | PIAS3 activates the intrinsic apoptotic pathway in non-small cell lung cancer cells independent of p53 status. |
| 25573684 (PIAS3) | PIAS3 expression in squamous cell lung cancer is low and predicts overall survival |
| 28988111 (PIAS3) | PAI-1 interacted with PIAS3 to regulate Stat3-dependent gene expression and miR-34a was transcriptionally suppressed by Stat3 to form a positive regulatory loop through Stat3 signaling in non-small cell lung cancer cells. |