lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

10211

PubMed (Gene Name)

Literature evidence

24533441 (FLOT1)

Flotillin-1 mRNA expression is up-regulated in non-small cell lung cancer patients.

27448302 (FLOT1)

Data show that overexpression of 4.1N protein decreased expression of flotillin-1, decreased activation of beta-catenin/Wnt pathway in non-small-cell lung cancer (NSCLC) cells.

30838797 (FLOT1)

Results show that FLOT1 promotes tumor development, induces epithelial-mesenchymal transition, and modulates the cell cycle in lung adenocarcinoma by simultaneously affecting the Erk and Akt signaling pathways.