Cancer metastasis database

Annotation category 5

Gene information

Gene ID 10211
Symbol

FLOT1

Synonymous

-

Full name

flotillin 1

Gene description

flotillin-1|integral membrane component of caveolae

Cytoband

6p21.3

Gene type

protein-coding

Synonymous

MIM:606998; HGNC:HGNC:3757; Ensembl:ENSG00000137312; HPRD:06105; Vega:OTTHUMG00000031151

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1060C>A; p.L354M; 6:30730457-30730457

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.472C>A; p.Q158K; 6:30740681-30740681

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.11C>T; p.T4I; 6:30742179-30742179

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.848T>G; p.V283G; 6:30730976-30730976

 breastcarcinomaSubstitution - Missense

c.956G>A; p.R319H; 6:30730561-30730561

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.711C>G; p.A237A; 6:30740170-30740170

 thyroidcarcinomaSubstitution - coding silent

c.1239C>T; p.G413G; 6:30730037-30730037

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.822G>A; p.R274R; 6:30731002-30731002

 skinmalignant_melanomaSubstitution - coding silent

c.994C>T; p.R332*; 6:30730523-30730523

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.503G>A; p.R168Q; 6:30740563-30740563

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.609C>T; p.Y203Y; 6:30740272-30740272

 prostatecarcinomaSubstitution - coding silent

c.100T>C; p.C34R; 6:30741811-30741811

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.83G>T; p.R28L; 6:30741828-30741828

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.269G>T; p.G90V; 6:30741275-30741275

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1240G>A; p.V414M; 6:30730036-30730036

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.758G>A; p.R253Q; 6:30731066-30731066

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.664G>A; p.A222T; 6:30740217-30740217

 thyroidcarcinomaSubstitution - Missense

c.245C>A; p.A82E; 6:30741299-30741299

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.525T>G; p.D175E; 6:30740541-30740541

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.615T>C; p.S205S; 6:30740266-30740266

 skinmalignant_melanomaSubstitution - coding silent

c.571-1G>A; p.?; 6:30740311-30740311

 skinmalignant_melanomaUnknown

c.187A>C; p.I63L; 6:30741637-30741637

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.712T>C; p.Y238H; 6:30740169-30740169

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1139T>C; p.L380P; 6:30730137-30730137

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1139T>C; p.L380P; 6:30730137-30730137

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1139T>C; p.L380P; 6:30730137-30730137

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1020G>C; p.K340N; 6:30730497-30730497

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.264C>T; p.F88F; 6:30741280-30741280

 skinmalignant_melanomaSubstitution - coding silent

c.333C>G; p.I111M; 6:30741211-30741211

 breastcarcinomaSubstitution - Missense

c.377A>T; p.K126I; 6:30740776-30740776

 thyroidother; neoplasmSubstitution - Missense

c.1184G>C; p.G395A; 6:30730092-30730092

 pancreascarcinoid-endocrine_tumourSubstitution - Missense

c.568C>T; p.R190W; 6:30740498-30740498

 central_nervous_system; braingliomaSubstitution - Missense

c.681C>G; p.V227V; 6:30740200-30740200

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1112C>T; p.P371L; 6:30730164-30730164

 skin; anklemalignant_melanoma; acral_lentiginousSubstitution - Missense

c.324G>A; p.Q108Q; 6:30741220-30741220

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.724-1G>T; p.?; 6:30731101-30731101

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.529C>T; p.R177W; 6:30740537-30740537

 pancreascarcinomaSubstitution - Missense

c.1219A>C; p.S407R; 6:30730057-30730057

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.428G>A; p.G143D; 6:30740725-30740725

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.905+8T>C; p.?; 6:30730911-30730911

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.1121C>T; p.S374L; 6:30730155-30730155

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.972C>G; p.A324A; 6:30730545-30730545

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.746T>C; p.I249T; 6:30731078-30731078

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.746T>C; p.I249T; 6:30731078-30731078

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.1113C>T; p.P371P; 6:30730163-30730163

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1233C>G; p.L411L; 6:30730043-30730043

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1006G>A; p.E336K; 6:30730511-30730511

 pancreascarcinomaSubstitution - Missense

c.308C>T; p.T103M; 6:30741236-30741236

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.211-1G>T; p.?; 6:30741334-30741334

 ovaryother; neoplasmUnknown

c.211-1G>T; p.?; 6:30741334-30741334

 ovaryother; neoplasmUnknown

c.943T>C; p.S315P; 6:30730690-30730690

 skinmalignant_melanomaSubstitution - Missense

c.276G>A; p.T92T; 6:30741268-30741268

 livercarcinomaSubstitution - coding silent

c.276G>A; p.T92T; 6:30741268-30741268

 prostateadenomaSubstitution - coding silent

c.782G>A; p.R261Q; 6:30731042-30731042

 breastcarcinomaSubstitution - Missense

c.210+2T>C; p.?; 6:30741612-30741612

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.934G>A; p.E312K; 6:30730699-30730699

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.958G>T; p.G320W; 6:30730559-30730559

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.431T>C; p.I144T; 6:30740722-30740722

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense