Cancer metastasis database

Annotation category 5

Gene information

Gene ID 9052
Symbol

GPRC5A

Synonymous

GPCR5A|PEIG-1|RAI3|RAIG1|TIG1

Full name

G protein-coupled receptor, class C, group 5, member A

Gene description

G protein-coupled receptor, family C, group 5, member A|G-protein coupled receptor family C group 5 member A|TPA induced gene 1|orphan G-protein-coupling receptor PEIG-1|phorbol ester induced protein-1|retinoic acid induced 3|retinoic acid responsive|reti

Cytoband

12p13.1

Gene type

protein-coding

Synonymous

MIM:604138; HGNC:HGNC:9836; HPRD:16037

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.733C>T; p.L245F; 12:12908982-12908982

 skinmalignant_melanomaSubstitution - Missense

c.712C>T; p.R238C; 12:12908961-12908961

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.945G>A; p.T315T; 12:12912106-12912106

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.289C>G; p.R97G; 12:12908538-12908538

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.149C>T; p.P50L; 12:12908398-12908398

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.370C>T; p.R124W; 12:12908619-12908619

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.370C>T; p.R124W; 12:12908619-12908619

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.355C>T; p.L119L; 12:12908604-12908604

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.371G>A; p.R124Q; 12:12908620-12908620

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.371G>A; p.R124Q; 12:12908620-12908620

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.90C>T; p.V30V; 12:12908339-12908339

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.414C>T; p.A138A; 12:12908663-12908663

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.216C>T; p.L72L; 12:12908465-12908465

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.216C>T; p.L72L; 12:12908465-12908465

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.216C>T; p.L72L; 12:12908465-12908465

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.741C>T; p.S247S; 12:12908990-12908990

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.719G>A; p.W240*; 12:12908968-12908968

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.472A>G; p.N158D; 12:12908721-12908721

 skinmalignant_melanomaSubstitution - Missense

c.537C>T; p.L179L; 12:12908786-12908786

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.587C>T; p.S196F; 12:12908836-12908836

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.484G>A; p.V162I; 12:12908733-12908733

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.540G>T; p.L180L; 12:12908789-12908789

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.636C>T; p.H212H; 12:12908885-12908885

 upper_aerodigestive_tract; larynxcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.305G>T; p.G102V; 12:12908554-12908554

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.366C>T; p.L122L; 12:12908615-12908615

 skinmalignant_melanomaSubstitution - coding silent

c.313T>G; p.F105V; 12:12908562-12908562

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1024G>A; p.A342T; 12:12912489-12912489

 stomachadenocarcinomaSubstitution - Missense

c.609C>T; p.F203F; 12:12908858-12908858

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.648G>A; p.T216T; 12:12908897-12908897

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.907G>C; p.E303Q; 12:12909156-12909156

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.318C>T; p.S106S; 12:12908567-12908567

 skinmalignant_melanomaSubstitution - coding silent

c.88G>A; p.V30I; 12:12908337-12908337

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.156C>T; p.L52L; 12:12908405-12908405

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.156C>T; p.L52L; 12:12908405-12908405

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.88G>A; p.V30I; 12:12908337-12908337

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.88G>A; p.V30I; 12:12908337-12908337

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1035C>T; p.S345S; 12:12912500-12912500

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.815G>A; p.R272Q; 12:12909064-12909064

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.815G>A; p.R272Q; 12:12909064-12909064

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.90_91CC>TT; p.(=); 12:12908339-12908340

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.383C>G; p.P128R; 12:12908632-12908632

 livercarcinomaSubstitution - Missense

c.651G>T; p.M217I; 12:12908900-12908900

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.523G>T; p.E175*; 12:12908772-12908772

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.700C>T; p.P234S; 12:12908949-12908949

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.156C>A; p.L52L; 12:12908405-12908405

 pancreascarcinomaSubstitution - coding silent

c.973C>T; p.Q325*; 12:12912134-12912134

 skinmalignant_melanomaSubstitution - Nonsense

c.329C>T; p.S110F; 12:12908578-12908578

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.111C>T; p.A37A; 12:12908360-12908360

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.111C>T; p.A37A; 12:12908360-12908360

 thyroidother; neoplasmSubstitution - coding silent

c.329C>T; p.S110F; 12:12908578-12908578

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.369C>T; p.V123V; 12:12908618-12908618

 skinmalignant_melanomaSubstitution - coding silent

c.1007C>A; p.S336Y; 12:12912472-12912472

 breastcarcinomaSubstitution - Missense

c.1063G>C; p.E355Q; 12:12912528-12912528

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.328T>A; p.S110T; 12:12908577-12908577

 breastcarcinomaSubstitution - Missense

c.580A>G; p.M194V; 12:12908829-12908829

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.376A>G; p.R126G; 12:12908625-12908625

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.753C>T; p.A251A; 12:12909002-12909002

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.597C>T; p.F199F; 12:12908846-12908846

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.270C>T; p.D90D; 12:12908519-12908519

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.183delG; p.R61fs*59; 12:12908432-12908432

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; hairy_cell_leukaemiaDeletion - Frameshift

c.642C>T; p.Y214Y; 12:12908891-12908891

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.629G>A; p.G210E; 12:12908878-12908878

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.680G>T; p.W227L; 12:12908929-12908929

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1069A>G; p.S357G; 12:12912534-12912534

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.508G>C; p.A170P; 12:12908757-12908757

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.312C>T; p.L104L; 12:12908561-12908561

 skinmalignant_melanomaSubstitution - coding silent

c.771G>A; p.L257L; 12:12909020-12909020

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.184C>T; p.R62*; 12:12908433-12908433

 bone; extraskeletalEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Nonsense

c.384C>T; p.P128P; 12:12908633-12908633

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.814C>T; p.R272*; 12:12909063-12909063

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.390C>T; p.S130S; 12:12908639-12908639

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.99G>A; p.T33T; 12:12908348-12908348

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.262G>A; p.G88R; 12:12908511-12908511

 skinmalignant_melanomaSubstitution - Missense