lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	81037
Symbol	CLPTM1L
Synonymous	CRR9
Full name	CLPTM1-like
Gene description	CLPTM1-like protein\|CRR9p\|cisplatin resistance related protein CRR9p\|cisplatin resistance-related protein 9\|cleft lip and palate transmembrane protein 1-like protein
Cytoband	5p15.33
Gene type	protein-coding
Synonymous	MIM:612585; HGNC:HGNC:24308; Ensembl:ENSG00000049656; HPRD:07480; Vega:OTTHUMG00000131015

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.675G>A; p.L225L; 5:1337907-1337907	skin	malignant_melanoma	Substitution - coding silent
c.1276A>T; p.K426*; 5:1323791-1323791	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.586C>T; p.R196W; 5:1338873-1338873	skin; extremity	malignant_melanoma	Substitution - Missense
c.957C>G; p.I319M; 5:1331818-1331818	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1034C>T; p.T345M; 5:1330326-1330326	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.619G>A; p.V207M; 5:1337963-1337963	thyroid	other; neoplasm	Substitution - Missense
c.214G>A; p.D72N; 5:1344400-1344400	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1025A>G; p.D342G; 5:1330335-1330335	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.338C>A; p.A113D; 5:1341786-1341786	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.944A>G; p.K315R; 5:1331831-1331831	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1550A>G; p.K517R; 5:1318436-1318436	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1550A>G; p.K517R; 5:1318436-1318436	stomach	adenocarcinoma	Substitution - Missense
c.317C>T; p.A106V; 5:1341807-1341807	skin	malignant_melanoma	Substitution - Missense
c.616delA; p.T206fs*17; 5:1337966-1337966	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.884C>T; p.A295V; 5:1334296-1334296	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1132A>T; p.M378L; 5:1325765-1325765	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.255A>C; p.K85N; 5:1344359-1344359	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.587G>A; p.R196Q; 5:1338872-1338872	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1595C>T; p.T532M; 5:1318391-1318391	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1595C>T; p.T532M; 5:1318391-1318391	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1595C>T; p.T532M; 5:1318391-1318391	large_intestine; colon	carcinoma	Substitution - Missense
c.1526A>G; p.Q509R; 5:1320622-1320622	liver	carcinoma	Substitution - Missense
c.223T>G; p.L75V; 5:1344391-1344391	skin	malignant_melanoma	Substitution - Missense
c.487C>T; p.L163L; 5:1338972-1338972	skin	malignant_melanoma	Substitution - coding silent
c.753C>G; p.F251L; 5:1335100-1335100	breast	carcinoma	Substitution - Missense
c.1128_1129CC>AA; p.L377M; 5:1325768-1325769	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.662G>A; p.R221H; 5:1337920-1337920	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.661C>T; p.R221C; 5:1337921-1337921	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1582G>A; p.E528K; 5:1318404-1318404	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.661C>T; p.R221C; 5:1337921-1337921	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.710T>C; p.L237P; 5:1335143-1335143	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1297A>G; p.I433V; 5:1322895-1322895	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.939G>T; p.K313N; 5:1331836-1331836	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.540G>T; p.A180A; 5:1338919-1338919	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1062T>G; p.G354G; 5:1330298-1330298	breast	carcinoma	Substitution - coding silent
c.796G>A; p.G266R; 5:1335057-1335057	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.581T>A; p.V194E; 5:1338878-1338878	urinary_tract; bladder	carcinoma	Substitution - Missense
c.909G>T; p.L303L; 5:1331866-1331866	pancreas	carcinoma	Substitution - coding silent
c.879C>T; p.V293V; 5:1334301-1334301	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.879C>T; p.V293V; 5:1334301-1334301	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.965C>T; p.S322F; 5:1331810-1331810	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1289C>A; p.S430Y; 5:1322903-1322903	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1587G>C; p.E529D; 5:1318399-1318399	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1034C>G; p.T345R; 5:1330326-1330326	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.143C>T; p.A48V; 5:1344699-1344699	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1072G>A; p.A358T; 5:1330288-1330288	central_nervous_system; brain	glioma	Substitution - Missense
c.531C>T; p.N177N; 5:1338928-1338928	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.885G>A; p.A295A; 5:1334295-1334295	breast	carcinoma	Substitution - coding silent
c.531C>T; p.N177N; 5:1338928-1338928	skin	malignant_melanoma	Substitution - coding silent
c.476C>T; p.P159L; 5:1338983-1338983	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1300A>G; p.N434D; 5:1322892-1322892	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1300A>G; p.N434D; 5:1322892-1322892	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1440C>T; p.D480D; 5:1320708-1320708	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.323T>A; p.I108N; 5:1341801-1341801	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1195C>G; p.Q399E; 5:1324765-1324765	breast	carcinoma	Substitution - Missense
c.1187A>G; p.Y396C; 5:1324773-1324773	skin	malignant_melanoma	Substitution - Missense
c.56A>G; p.Y19C; 5:1344786-1344786	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1477C>T; p.R493W; 5:1320671-1320671	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.837delT; p.F279fs*2; 5:1334343-1334343	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.959G>A; p.G320D; 5:1331816-1331816	pancreas	carcinoma	Substitution - Missense
c.959G>A; p.G320D; 5:1331816-1331816	prostate	carcinoma	Substitution - Missense
c.957C>T; p.I319I; 5:1331818-1331818	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.405C>T; p.V135V; 5:1341719-1341719	skin; trunk	malignant_melanoma; nodular	Substitution - coding silent
c.1131G>A; p.L377L; 5:1325766-1325766	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.852A>T; p.L284F; 5:1334328-1334328	oesophagus	carcinoma	Substitution - Missense
c.976+3A>T; p.?; 5:1331796-1331796	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.221T>C; p.V74A; 5:1344393-1344393	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.646G>A; p.D216N; 5:1337936-1337936	skin; mucosal	malignant_melanoma	Substitution - Missense
c.1601C>T; p.A534V; 5:1318385-1318385	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.528G>A; p.L176L; 5:1338931-1338931	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.741G>A; p.G247G; 5:1335112-1335112	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.351G>A; p.P117P; 5:1341773-1341773	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.171G>A; p.V57V; 5:1344443-1344443	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.947_949delAGA; p.K316delK; 5:1331826-1331828	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - In frame
c.724G>A; p.D242N; 5:1335129-1335129	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1498G>A; p.D500N; 5:1320650-1320650	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1228C>T; p.P410S; 5:1323839-1323839	skin	malignant_melanoma	Substitution - Missense
c.1469C>T; p.T490M; 5:1320679-1320679	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1498G>A; p.D500N; 5:1320650-1320650	breast	carcinoma	Substitution - Missense
c.529A>T; p.N177Y; 5:1338930-1338930	skin	malignant_melanoma	Substitution - Missense
c.1058C>T; p.A353V; 5:1330302-1330302	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.928A>G; p.S310G; 5:1331847-1331847	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1058C>T; p.A353V; 5:1330302-1330302	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.222C>T; p.V74V; 5:1344392-1344392	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1148T>A; p.F383Y; 5:1324812-1324812	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.623A>G; p.H208R; 5:1337959-1337959	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.243T>C; p.D81D; 5:1344371-1344371	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1602G>A; p.A534A; 5:1318384-1318384	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1239C>T; p.V413V; 5:1323828-1323828	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.538G>A; p.A180T; 5:1338921-1338921	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1281-3C>A; p.?; 5:1322914-1322914	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Unknown
c.1168G>A; p.E390K; 5:1324792-1324792	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1198G>T; p.A400S; 5:1323869-1323869	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1492C>T; p.R498W; 5:1320656-1320656	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1056G>A; p.P352P; 5:1330304-1330304	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.329T>C; p.L110P; 5:1341795-1341795	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.566_567CC>TT; p.S189F; 5:1338892-1338893	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.567C>T; p.S189S; 5:1338892-1338892	skin	malignant_melanoma	Substitution - coding silent
c.123C>T; p.N41N; 5:1344719-1344719	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.783C>T; p.S261S; 5:1335070-1335070	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.435C>T; p.T145T; 5:1341689-1341689	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.394A>G; p.T132A; 5:1341730-1341730	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.153delC; p.K52fs*4; 5:1344689-1344689	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.873_875delCTT; p.F292delF; 5:1334305-1334307	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - In frame
c.1166C>T; p.S389F; 5:1324794-1324794	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1291T>C; p.W431R; 5:1322901-1322901	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.749G>A; p.R250H; 5:1335104-1335104	prostate	adenoma	Substitution - Missense
c.1417-1G>T; p.?; 5:1320732-1320732	autonomic_ganglia	neuroblastoma	Unknown
c.479C>T; p.T160M; 5:1338980-1338980	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1214C>T; p.S405L; 5:1323853-1323853	skin	malignant_melanoma	Substitution - Missense
c.1426A>G; p.T476A; 5:1320722-1320722	liver	carcinoma	Substitution - Missense
c.524C>T; p.A175V; 5:1338935-1338935	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1120delT; p.W374fs*4; 5:1325777-1325777	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1394C>T; p.P465L; 5:1321657-1321657	skin	malignant_melanoma	Substitution - Missense
c.313T>C; p.Y105H; 5:1341811-1341811	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1120delT; p.W374fs*4; 5:1325777-1325777	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.618C>T; p.T206T; 5:1337964-1337964	skin	malignant_melanoma	Substitution - coding silent
c.452A>C; p.Q151P; 5:1341672-1341672	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.181A>G; p.T61A; 5:1344433-1344433	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1597C>T; p.R533W; 5:1318389-1318389	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1597C>T; p.R533W; 5:1318389-1318389	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1597C>T; p.R533W; 5:1318389-1318389	large_intestine; colon	carcinoma	Substitution - Missense
c.1597C>T; p.R533W; 5:1318389-1318389	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1493G>A; p.R498Q; 5:1320655-1320655	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1612G>A; p.D538N; 5:1318374-1318374	liver	carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation