Cancer metastasis database

Annotation category 5

Gene information

Gene ID 6422
Symbol

SFRP1

Synonymous

FRP|FRP-1|FRP1|FrzA|SARP2

Full name

secreted frizzled-related protein 1

Gene description

SARP-2|sFRP-1|secreted apoptosis-related protein 2

Cytoband

8p11.21

Gene type

protein-coding

Synonymous

MIM:604156; HGNC:HGNC:10776; Ensembl:ENSG00000104332; HPRD:09165; Vega:OTTHUMG00000164074

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.370C>T; p.R124W; 8:41308790-41308790

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.222G>T; p.K74N; 8:41308938-41308938

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.93C>T; p.A31A; 8:41309067-41309067

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.648G>A; p.V216V; 8:41265464-41265464

 skinmalignant_melanomaSubstitution - coding silent

c.441C>T; p.F147F; 8:41308719-41308719

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.492C>T; p.D164D; 8:41308668-41308668

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.589G>A; p.A197T; 8:41303494-41303494

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.661G>T; p.G221C; 8:41265451-41265451

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.668A>C; p.K223T; 8:41265444-41265444

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.823G>A; p.V275M; 8:41265289-41265289

 skinmalignant_melanomaSubstitution - Missense

c.457G>A; p.E153K; 8:41308703-41308703

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.262G>A; p.A88T; 8:41308898-41308898

 breastcarcinomaSubstitution - Missense

c.714C>G; p.I238M; 8:41265398-41265398

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.262G>A; p.A88T; 8:41308898-41308898

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.281C>T; p.A94V; 8:41308879-41308879

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.139C>A; p.Q47K; 8:41309021-41309021

 livercarcinomaSubstitution - Missense

c.139C>A; p.Q47K; 8:41309021-41309021

 livercarcinomaSubstitution - Missense

c.889T>C; p.F297L; 8:41265223-41265223

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.260T>C; p.M87T; 8:41308900-41308900

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.73C>T; p.L25F; 8:41309087-41309087

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.92C>A; p.A31D; 8:41309068-41309068

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.195G>T; p.L65L; 8:41308965-41308965

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.523A>C; p.T175P; 8:41308637-41308637

 breastcarcinomaSubstitution - Missense

c.880T>C; p.F294L; 8:41265232-41265232

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.665A>T; p.D222V; 8:41265447-41265447

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.643G>A; p.E215K; 8:41265469-41265469

 skin; head_neckmalignant_melanoma; superficial_spreadingSubstitution - Missense

c.484G>T; p.E162*; 8:41308676-41308676

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.534C>T; p.S178S; 8:41308626-41308626

 skinmalignant_melanomaSubstitution - coding silent

c.934G>A; p.V312M; 8:41265178-41265178

 breastcarcinomaSubstitution - Missense

c.66C>T; p.G22G; 8:41309094-41309094

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.490delG; p.D164fs*6; 8:41308670-41308670

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.591C>T; p.A197A; 8:41303492-41303492

 stomachadenocarcinomaSubstitution - coding silent

c.746A>G; p.Y249C; 8:41265366-41265366

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.537G>T; p.K179N; 8:41308623-41308623

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.860G>A; p.W287*; 8:41265252-41265252

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.792C>T; p.L264L; 8:41265320-41265320

 breastcarcinomaSubstitution - coding silent

c.643G>T; p.E215*; 8:41265469-41265469

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.400G>A; p.E134K; 8:41308760-41308760

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.39_41delAGC; p.A14delA; 8:41309119-41309121

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.132C>A; p.G44G; 8:41309028-41309028

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.132C>A; p.G44G; 8:41309028-41309028

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - coding silent

c.684G>A; p.K228K; 8:41265428-41265428

 skinmalignant_melanomaSubstitution - coding silent

c.39_41delAGC; p.A14delA; 8:41309119-41309121

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.39_41delAGC; p.A14delA; 8:41309119-41309121

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; myelofibrosisDeletion - In frame

c.80C>T; p.A27V; 8:41309080-41309080

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.80C>T; p.A27V; 8:41309080-41309080

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.862G>A; p.D288N; 8:41265250-41265250

 skinmalignant_melanomaSubstitution - Missense

c.822G>A; p.K274K; 8:41265290-41265290

 skinmalignant_melanomaSubstitution - coding silent

c.239A>G; p.N80S; 8:41308921-41308921

 skinmalignant_melanomaSubstitution - Missense

c.883A>C; p.K295Q; 8:41265229-41265229

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.552G>A; p.T184T; 8:41303531-41303531

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.616G>A; p.E206K; 8:41303467-41303467

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.410G>A; p.R137H; 8:41308750-41308750

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Missense

c.410G>A; p.R137H; 8:41308750-41308750

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense