Cancer metastasis database

Annotation category 5

Gene information

Gene ID 6319
Symbol

SCD

Synonymous

FADS5|MSTP008|SCD1|SCDOS

Full name

stearoyl-CoA desaturase (delta-9-desaturase)

Gene description

acyl-CoA desaturase|delta(9)-desaturase|delta-9 desaturase|delta-9-desaturase|fatty acid desaturase|predicted protein of HQ0998|stearoyl-CoA desaturase opposite strand

Cytoband

10q24.31

Gene type

protein-coding

Synonymous

MIM:604031; HGNC:HGNC:10571; Ensembl:ENSG00000099194; HPRD:04941; Vega:OTTHUMG00000018906

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.982G>A; p.A328T; 10:100360835-100360835

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.884A>G; p.E295G; 10:100360737-100360737

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.520C>T; p.R174*; 10:100354505-100354505

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.848G>A; p.R283Q; 10:100356732-100356732

 livercarcinomaSubstitution - Missense

c.651C>T; p.Y217Y; 10:100356535-100356535

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.848G>A; p.R283Q; 10:100356732-100356732

 livercarcinomaSubstitution - Missense

c.544G>A; p.V182M; 10:100354529-100354529

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1040G>A; p.R347K; 10:100360893-100360893

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.766G>A; p.V256M; 10:100356650-100356650

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1019C>A; p.S340Y; 10:100360872-100360872

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.741C>T; p.F247F; 10:100356625-100356625

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.810C>T; p.L270L; 10:100356694-100356694

 skinmalignant_melanomaSubstitution - coding silent

c.376C>A; p.R126S; 10:100352431-100352431

 livercarcinomaSubstitution - Missense

c.66G>A; p.A22A; 10:100348102-100348102

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.66G>A; p.A22A; 10:100348102-100348102

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.376C>A; p.R126S; 10:100352431-100352431

 livercarcinomaSubstitution - Missense

c.243G>T; p.L81L; 10:100348279-100348279

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.719A>G; p.E240G; 10:100356603-100356603

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.653A>G; p.Y218C; 10:100356537-100356537

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.875C>T; p.A292V; 10:100356759-100356759

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1061G>T; p.G354V; 10:100360914-100360914

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.852G>A; p.E284E; 10:100356736-100356736

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.439C>T; p.Q147*; 10:100352494-100352494

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.309G>C; p.W103C; 10:100348345-100348345

 breastcarcinomaSubstitution - Missense

c.670A>C; p.M224L; 10:100356554-100356554

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.203A>C; p.K68T; 10:100348239-100348239

 livercarcinomaSubstitution - Missense

c.294C>A; p.F98L; 10:100348330-100348330

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1049G>T; p.R350I; 10:100360902-100360902

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.442-1G>A; p.?; 10:100354426-100354426

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaUnknown

c.442-1G>A; p.?; 10:100354426-100354426

 urinary_tract; bladdercarcinomaUnknown

c.908C>A; p.S303Y; 10:100360761-100360761

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.742G>A; p.V248I; 10:100356626-100356626

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.311-1G>T; p.?; 10:100352365-100352365

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.400C>G; p.L134V; 10:100352455-100352455

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.564C>T; p.R188R; 10:100354549-100354549

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1006C>T; p.R336W; 10:100360859-100360859

 oesophaguscarcinomaSubstitution - Missense

c.391C>T; p.R131W; 10:100352446-100352446

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.940C>T; p.R314C; 10:100360793-100360793

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1059T>A; p.D353E; 10:100360912-100360912

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.464G>C; p.R155P; 10:100354449-100354449

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.266G>T; p.G89V; 10:100348302-100348302

 skinmalignant_melanomaSubstitution - Missense

c.372C>T; p.S124S; 10:100352427-100352427

 central_nervous_system; braingliomaSubstitution - coding silent

c.985G>A; p.A329T; 10:100360838-100360838

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.30C>T; p.I10I; 10:100348066-100348066

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.985G>A; p.A329T; 10:100360838-100360838

 livercarcinomaSubstitution - Missense

c.985G>A; p.A329T; 10:100360838-100360838

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.309G>A; p.W103*; 10:100348345-100348345

 skinmalignant_melanomaSubstitution - Nonsense

c.521G>A; p.R174Q; 10:100354506-100354506

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1060G>C; p.G354R; 10:100360913-100360913

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.15G>T; p.L5F; 10:100347519-100347519

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense