| Gene ID | 51741 |
| Symbol | WWOX |
| Synonymous | D16S432E|EIEE28|FOR|FRA16D|HHCMA56|PRO0128|SCAR12|SDR41C1|WOX1 |
| Full name | WW domain containing oxidoreductase |
| Gene description | WW domain-containing oxidoreductase|WW domain-containing protein WWOX|fragile site FRA16D oxidoreductase|short chain dehydrogenase/reductase family 41C member 1|short chain dehydrogenase/reductase family 41C, member 1 |
| Cytoband | 16q23 |
| Gene type | protein-coding |
| Synonymous | MIM:605131; HGNC:HGNC:12799; Ensembl:ENSG00000186153; HPRD:05501; Vega:OTTHUMG00000176851 |
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.452T>C; p.V151A; 16:78164225-78164225 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.211G>A; p.G71R; 16:78109816-78109816 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.448C>G; p.H150D; 16:78164221-78164221 |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm; follicular_lymphoma | Substitution - Missense |
c.537G>A; p.P179P; 16:78278623-78278623 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.415G>A; p.E139K; 16:78164188-78164188 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.511G>T; p.E171*; 16:78164284-78164284 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.451G>C; p.V151L; 16:78164224-78164224 |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm; follicular_lymphoma | Substitution - Missense |
c.160C>T; p.R54*; 16:78108475-78108475 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.119A>T; p.E40V; 16:78108434-78108434 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.374A>G; p.K125R; 16:78115119-78115119 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.517-3C>A; p.?; 16:78278600-78278600 |
central_nervous_system; brainstem | glioma; astrocytoma_Grade_II | Unknown |
c.410G>T; p.G137V; 16:78164183-78164183 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.544A>G; p.K182E; 16:78278630-78278630 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm; acute_myeloid_leukaemia | Substitution - Missense |
c.556A>C; p.K186Q; 16:78278642-78278642 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.177G>A; p.L59L; 16:78109782-78109782 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - coding silent |
c.500G>A; p.R167H; 16:78164273-78164273 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.500G>A; p.R167H; 16:78164273-78164273 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.500G>A; p.R167H; 16:78164273-78164273 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.517-1G>A; p.?; 16:78278602-78278602 |
endometrium | carcinoma; serous_carcinoma | Unknown |
c.479G>T; p.R160M; 16:78164252-78164252 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.411G>A; p.G137G; 16:78164184-78164184 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - coding silent |
c.414C>T; p.F138F; 16:78164187-78164187 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.482C>T; p.A161V; 16:78164255-78164255 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.425A>T; p.K142M; 16:78164198-78164198 |
upper_aerodigestive_tract; mouth | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.454A>T; p.I152F; 16:78164227-78164227 |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm; follicular_lymphoma | Substitution - Missense |