Cancer metastasis database

Annotation category 5

Gene information

Gene ID 4968
Symbol

OGG1

Synonymous

HMMH|HOGG1|MUTM|OGH1

Full name

8-oxoguanine DNA glycosylase

Gene description

8-hydroxyguanine DNA glycosylase|AP lyase|DNA-apurinic or apyrimidinic site lyase|N-glycosylase/DNA lyase|OGG1 type 1f

Cytoband

3p26.2

Gene type

protein-coding

Synonymous

MIM:601982; HGNC:HGNC:8125; Ensembl:ENSG00000114026; HPRD:03582; Vega:OTTHUMG00000097091

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.852C>T; p.T284T; 3:9756575-9756575

 skin; trunkmalignant_melanoma; nodularSubstitution - coding silent

c.798C>T; p.P266P; 3:9756521-9756521

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1029G>A; p.P343P; 3:9757141-9757141

 breastcarcinomaSubstitution - coding silent

c.344C>T; p.S115F; 3:9751151-9751151

 skinmalignant_melanomaSubstitution - Missense

c.364G>T; p.E122*; 3:9751171-9751171

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.971G>A; p.R324H; 3:9757083-9757083

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.332A>G; p.H111R; 3:9751139-9751139

 stomachadenocarcinomaSubstitution - Missense

c.854C>T; p.T285M; 3:9756577-9756577

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.854C>T; p.T285M; 3:9756577-9756577

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.603G>C; p.L201L; 3:9754741-9754741

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.678G>T; p.Q226H; 3:9754816-9754816

 pancreascarcinoid-endocrine_tumourSubstitution - Missense

c.353C>T; p.S118F; 3:9751160-9751160

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.869G>A; p.G290E; 3:9756592-9756592

 breastcarcinomaSubstitution - Missense

c.193A>G; p.T65A; 3:9751000-9751000

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.414C>T; p.I138I; 3:9751798-9751798

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.391C>G; p.R131G; 3:9751775-9751775

 skinmalignant_melanomaSubstitution - Missense

c.174A>G; p.V58V; 3:9750981-9750981

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.830G>A; p.R277H; 3:9756553-9756553

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.111G>C; p.L37L; 3:9750397-9750397

 breastcarcinomaSubstitution - coding silent

c.441C>A; p.S147S; 3:9751825-9751825

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.180G>C; p.A60A; 3:9750987-9750987

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.457G>A; p.A153T; 3:9751841-9751841

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.872C>A; p.P291Q; 3:9756595-9756595

 skinmalignant_melanomaSubstitution - Missense

c.85C>A; p.P29T; 3:9750371-9750371

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.261G>A; p.R87R; 3:9751068-9751068

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.426C>A; p.F142L; 3:9751810-9751810

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.260G>A; p.R87K; 3:9751067-9751067

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.977C>G; p.S326C; 3:9757089-9757089

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.977C>G; p.S326C; 3:9757089-9757089

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.10C>T; p.R4C; 3:9750296-9750296

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.289C>T; p.R97C; 3:9751096-9751096

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.289C>T; p.R97C; 3:9751096-9751096

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1012A>G; p.K338E; 3:9757124-9757124

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1019C>T; p.S340F; 3:9757131-9757131

 skinmalignant_melanomaSubstitution - Missense