lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	4481
Symbol	MSR1
Synonymous	CD204\|SCARA1\|SR-A\|SRA\|phSR1\|phSR2
Full name	macrophage scavenger receptor 1
Gene description	macrophage acetylated LDL receptor I and II\|macrophage scavenger receptor type III\|macrophage scavenger receptor types I and II\|scavenger receptor class A member 1\|scavenger receptor class A, member 1
Cytoband	8p22
Gene type	protein-coding
Synonymous	MIM:153622; HGNC:HGNC:7376; Ensembl:ENSG00000038945; HPRD:01092; Vega:OTTHUMG00000094809

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.294G>A; p.T98T; 8:16168794-16168794	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.971G>A; p.G324E; 8:16150239-16150239	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.394G>A; p.E132K; 8:16168694-16168694	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.772G>T; p.D258Y; 8:16164110-16164110	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.394G>A; p.E132K; 8:16168694-16168694	skin; trunk	malignant_melanoma	Substitution - Missense
c.582A>G; p.I194M; 8:16168506-16168506	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1145G>A; p.R382H; 8:16120495-16120495	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.892C>T; p.P298S; 8:16155070-16155070	skin	malignant_melanoma	Substitution - Missense
c.363G>A; p.M121I; 8:16168725-16168725	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.363G>A; p.M121I; 8:16168725-16168725	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.892C>T; p.P298S; 8:16155070-16155070	skin; scalp	malignant_melanoma	Substitution - Missense
c.240G>A; p.T80T; 8:16168848-16168848	skin	malignant_melanoma	Substitution - coding silent
c.240G>A; p.T80T; 8:16168848-16168848	skin	malignant_melanoma	Substitution - coding silent
c.240G>A; p.T80T; 8:16168848-16168848	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.366G>A; p.E122E; 8:16168722-16168722	skin	malignant_melanoma	Substitution - coding silent
c.814C>T; p.Q272*; 8:16164068-16164068	skin	malignant_melanoma	Substitution - Nonsense
c.585A>C; p.E195D; 8:16168503-16168503	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.583G>T; p.E195*; 8:16168505-16168505	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.302G>A; p.G101E; 8:16168786-16168786	skin	malignant_melanoma	Substitution - Missense
c.302G>A; p.G101E; 8:16168786-16168786	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302G>A; p.G101E; 8:16168786-16168786	skin	malignant_melanoma	Substitution - Missense
c.302G>A; p.G101E; 8:16168786-16168786	skin	malignant_melanoma	Substitution - Missense
c.631G>A; p.E211K; 8:16164251-16164251	skin	malignant_melanoma	Substitution - Missense
c.196C>T; p.P66S; 8:16175208-16175208	skin	malignant_melanoma	Substitution - Missense
c.76C>T; p.R26C; 8:16177913-16177913	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.947G>T; p.S316I; 8:16150263-16150263	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.947G>T; p.S316I; 8:16150263-16150263	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.490T>C; p.S164P; 8:16168598-16168598	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1047A>C; p.K349N; 8:16120593-16120593	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.296G>A; p.G99E; 8:16168792-16168792	skin	malignant_melanoma	Substitution - Missense
c.104-1G>T; p.?; 8:16175301-16175301	lung	carcinoma; adenocarcinoma	Unknown
c.528C>T; p.I176I; 8:16168560-16168560	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1267G>A; p.E423K; 8:16110174-16110174	skin	malignant_melanoma	Substitution - Missense
c.1267G>A; p.E423K; 8:16110174-16110174	skin	malignant_melanoma	Substitution - Missense
c.923G>T; p.R308L; 8:16150287-16150287	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1161C>A; p.V387V; 8:16120479-16120479	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.774T>C; p.D258D; 8:16164108-16164108	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.723A>C; p.K241N; 8:16164159-16164159	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.818-1G>T; p.?; 8:16155145-16155145	stomach	carcinoma; adenocarcinoma	Unknown
c.565G>A; p.D189N; 8:16168523-16168523	skin	malignant_melanoma	Substitution - Missense
c.1059C>T; p.V353V; 8:16120581-16120581	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.653G>C; p.R218P; 8:16164229-16164229	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.634A>T; p.I212F; 8:16164248-16164248	oesophagus	carcinoma	Substitution - Missense
c.449A>C; p.Q150P; 8:16168639-16168639	central_nervous_system; brain	glioma	Substitution - Missense
c.103+1G>T; p.?; 8:16177885-16177885	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.599A>C; p.K200T; 8:16168489-16168489	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.981A>C; p.G327G; 8:16143610-16143610	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.409G>A; p.D137N; 8:16168679-16168679	skin	malignant_melanoma	Substitution - Missense
c.1009G>A; p.E337K; 8:16143582-16143582	skin	malignant_melanoma	Substitution - Missense
c.988G>A; p.G330R; 8:16143603-16143603	skin	malignant_melanoma	Substitution - Missense
c.1015G>A; p.G339R; 8:16143576-16143576	skin; scalp	malignant_melanoma	Substitution - Missense
c.1195G>A; p.V399M; 8:16120445-16120445	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.810A>T; p.L270F; 8:16164072-16164072	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1302G>A; p.W434*; 8:16110139-16110139	skin	malignant_melanoma	Substitution - Nonsense
c.312C>T; p.S104S; 8:16168776-16168776	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1051C>A; p.R351R; 8:16120589-16120589	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.724G>A; p.G242R; 8:16164158-16164158	skin	malignant_melanoma	Substitution - Missense
c.1263G>A; p.G421G; 8:16110178-16110178	skin	malignant_melanoma	Substitution - coding silent
c.58T>A; p.S20T; 8:16177931-16177931	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1068C>A; p.S356R; 8:16120572-16120572	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.935G>A; p.G312D; 8:16150275-16150275	skin	malignant_melanoma	Substitution - Missense
c.980G>A; p.G327E; 8:16143611-16143611	skin	malignant_melanoma	Substitution - Missense
c.980G>A; p.G327E; 8:16143611-16143611	skin	malignant_melanoma	Substitution - Missense
c.307G>T; p.D103Y; 8:16168781-16168781	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.877C>T; p.R293*; 8:16155085-16155085	oesophagus	carcinoma	Substitution - Nonsense
c.1186G>A; p.V396I; 8:16120454-16120454	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.306T>G; p.N102K; 8:16168782-16168782	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1111T>A; p.W371R; 8:16120529-16120529	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.306T>G; p.N102K; 8:16168782-16168782	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.491C>T; p.S164F; 8:16168597-16168597	skin	malignant_melanoma	Substitution - Missense
c.279A>G; p.I93M; 8:16168809-16168809	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.898G>T; p.G300C; 8:16155064-16155064	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.766C>G; p.L256V; 8:16164116-16164116	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.898G>T; p.G300C; 8:16155064-16155064	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.1033+1G>T; p.?; 8:16143557-16143557	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Unknown
c.1223-1G>A; p.?; 8:16110219-16110219	ovary	carcinoma; serous_carcinoma	Unknown
c.338T>C; p.V113A; 8:16168750-16168750	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1306A>G; p.T436A; 8:16110135-16110135	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.289C>T; p.L97F; 8:16168799-16168799	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.448C>A; p.Q150K; 8:16168640-16168640	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.375C>T; p.I125I; 8:16168713-16168713	skin	malignant_melanoma	Substitution - coding silent
c.334G>T; p.E112*; 8:16168754-16168754	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.907G>A; p.G303S; 8:16150303-16150303	skin	malignant_melanoma	Substitution - Missense
c.59C>A; p.S20Y; 8:16177930-16177930	breast	carcinoma	Substitution - Missense
c.976C>T; p.P326S; 8:16150234-16150234	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.557C>T; p.T186I; 8:16168531-16168531	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.714G>A; p.Q238Q; 8:16164168-16164168	skin	malignant_melanoma	Substitution - coding silent
c.847G>T; p.D283Y; 8:16155115-16155115	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1136G>A; p.W379*; 8:16120504-16120504	liver	carcinoma	Substitution - Nonsense
c.900T>A; p.G300G; 8:16150310-16150310	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1077C>T; p.H359H; 8:16120563-16120563	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1077C>T; p.H359H; 8:16120563-16120563	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1077C>T; p.H359H; 8:16120563-16120563	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1077C>T; p.H359H; 8:16120563-16120563	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1136G>A; p.W379*; 8:16120504-16120504	liver	carcinoma	Substitution - Nonsense
c.1219C>G; p.Q407E; 8:16120421-16120421	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.184G>C; p.A62P; 8:16175220-16175220	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; non_functioning	Substitution - Missense
c.116G>A; p.S39N; 8:16175288-16175288	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.106C>T; p.P36S; 8:16175298-16175298	skin	malignant_melanoma	Substitution - Missense
c.217G>A; p.A73T; 8:16175187-16175187	skin	malignant_melanoma	Substitution - Missense
c.704A>G; p.H235R; 8:16164178-16164178	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.319G>A; p.E107K; 8:16168769-16168769	skin	malignant_melanoma	Substitution - Missense
c.319G>A; p.E107K; 8:16168769-16168769	skin; ear	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1153C>A; p.Q385K; 8:16120487-16120487	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.319G>A; p.E107K; 8:16168769-16168769	skin	malignant_melanoma	Substitution - Missense
c.319G>A; p.E107K; 8:16168769-16168769	skin	malignant_melanoma	Substitution - Missense
c.1337G>T; p.G446V; 8:16110104-16110104	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1261G>C; p.G421R; 8:16110180-16110180	breast	carcinoma	Substitution - Missense
c.980-1G>A; p.?; 8:16143612-16143612	skin	malignant_melanoma	Unknown
c.649G>A; p.E217K; 8:16164233-16164233	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1044G>A; p.T348T; 8:16120596-16120596	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1044G>A; p.T348T; 8:16120596-16120596	skin	malignant_melanoma	Substitution - coding silent
c.823C>G; p.P275A; 8:16155139-16155139	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.823C>G; p.P275A; 8:16155139-16155139	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.823C>G; p.P275A; 8:16155139-16155139	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.946A>C; p.S316R; 8:16150264-16150264	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.195C>T; p.I65I; 8:16175209-16175209	skin	malignant_melanoma	Substitution - coding silent
c.823C>G; p.P275A; 8:16155139-16155139	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1212C>T; p.H404H; 8:16120428-16120428	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.853G>T; p.G285C; 8:16155109-16155109	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.199C>T; p.L67F; 8:16175205-16175205	skin	malignant_melanoma	Substitution - Missense
c.1232C>A; p.P411Q; 8:16110209-16110209	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.856C>T; p.P286S; 8:16155106-16155106	skin	malignant_melanoma	Substitution - Missense
c.1007_1008GG>AA; p.G336E; 8:16143583-16143584	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1304G>A; p.G435E; 8:16110137-16110137	skin	malignant_melanoma	Substitution - Missense
c.1146C>T; p.R382R; 8:16120494-16120494	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.483C>A; p.T161T; 8:16168605-16168605	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.233G>A; p.W78*; 8:16168855-16168855	central_nervous_system; brain	glioma	Substitution - Nonsense
c.1051C>T; p.R351*; 8:16120589-16120589	skin	malignant_melanoma	Substitution - Nonsense
c.830C>T; p.P277L; 8:16155132-16155132	skin	malignant_melanoma	Substitution - Missense
c.1051C>T; p.R351*; 8:16120589-16120589	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.301G>A; p.G101R; 8:16168787-16168787	skin	malignant_melanoma	Substitution - Missense
c.274G>T; p.D92Y; 8:16168814-16168814	oesophagus	carcinoma	Substitution - Missense
c.957C>T; p.L319L; 8:16150253-16150253	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.604C>T; p.Q202*; 8:16168484-16168484	skin	malignant_melanoma	Substitution - Nonsense
c.1171T>C; p.L391L; 8:16120469-16120469	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.971delG; p.G324fs*21; 8:16150239-16150239	breast	carcinoma	Deletion - Frameshift
c.369G>A; p.K123K; 8:16168719-16168719	skin	malignant_melanoma	Substitution - coding silent
c.903T>C; p.P301P; 8:16150307-16150307	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.1007G>A; p.G336E; 8:16143584-16143584	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.371G>T; p.R124I; 8:16168717-16168717	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.961G>T; p.G321*; 8:16150249-16150249	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.204T>G; p.I68M; 8:16175200-16175200	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.178G>C; p.V60L; 8:16175226-16175226	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.127C>A; p.Q43K; 8:16175277-16175277	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1036C>T; p.P346S; 8:16120604-16120604	skin	malignant_melanoma	Substitution - Missense
c.313G>A; p.E105K; 8:16168775-16168775	skin	malignant_melanoma	Substitution - Missense
c.313G>A; p.E105K; 8:16168775-16168775	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1158C>T; p.V386V; 8:16120482-16120482	skin	malignant_melanoma	Substitution - coding silent
c.1158C>T; p.V386V; 8:16120482-16120482	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1075C>T; p.H359Y; 8:16120565-16120565	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1082G>A; p.G361E; 8:16120558-16120558	skin	malignant_melanoma	Substitution - Missense
c.103+1G>A; p.?; 8:16177885-16177885	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.1128C>T; p.D376D; 8:16120512-16120512	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.820C>T; p.P274S; 8:16155142-16155142	skin	malignant_melanoma	Substitution - Missense
c.1021G>A; p.G341R; 8:16143570-16143570	skin	malignant_melanoma	Substitution - Missense
c.1319C>T; p.S440L; 8:16110122-16110122	skin	malignant_melanoma	Substitution - Missense
c.1183G>T; p.G395C; 8:16120457-16120457	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1229G>A; p.G410D; 8:16110212-16110212	skin	malignant_melanoma	Substitution - Missense
c.905C>T; p.P302L; 8:16150305-16150305	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.77G>A; p.R26H; 8:16177912-16177912	peritoneum; appendix	other; pseudomyxoma_peritonei	Substitution - Missense
c.441A>G; p.T147T; 8:16168647-16168647	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.33G>A; p.Q11Q; 8:16177956-16177956	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.677T>C; p.I226T; 8:16164205-16164205	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.850C>T; p.R284*; 8:16155112-16155112	skin	malignant_melanoma	Substitution - Nonsense
c.850C>T; p.R284*; 8:16155112-16155112	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.13G>A; p.D5N; 8:16177976-16177976	skin	malignant_melanoma	Substitution - Missense
c.1222+1G>A; p.?; 8:16120417-16120417	skin; trunk	malignant_melanoma	Unknown
c.248G>A; p.C83Y; 8:16168840-16168840	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.324G>A; p.M108I; 8:16168764-16168764	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1275T>C; p.S425S; 8:16110166-16110166	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1282G>A; p.E428K; 8:16110159-16110159	soft_tissue; blood_vessel	angiosarcoma	Substitution - Missense
c.757G>T; p.D253Y; 8:16164125-16164125	urinary_tract; bladder	carcinoma	Substitution - Missense
c.757G>T; p.D253Y; 8:16164125-16164125	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.523G>T; p.E175*; 8:16168565-16168565	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; primary_central_nervous_system_lymphoma	Substitution - Nonsense
c.878G>A; p.R293Q; 8:16155084-16155084	skin	malignant_melanoma	Substitution - Missense
c.339C>A; p.V113V; 8:16168749-16168749	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.694_696delGAA; p.E232delE; 8:16164186-16164188	stomach	carcinoma; diffuse_adenocarcinoma	Deletion - In frame
c.851G>A; p.R284Q; 8:16155111-16155111	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.504A>T; p.G168G; 8:16168584-16168584	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.570G>T; p.L190F; 8:16168518-16168518	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.1314C>T; p.A438A; 8:16110127-16110127	skin	malignant_melanoma	Substitution - coding silent
c.944G>A; p.G315E; 8:16150266-16150266	skin	malignant_melanoma	Substitution - Missense
c.833C>T; p.P278L; 8:16155129-16155129	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.708G>T; p.L236F; 8:16164174-16164174	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1138G>A; p.E380K; 8:16120502-16120502	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1052G>T; p.R351L; 8:16120588-16120588	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.18C>T; p.H6H; 8:16177971-16177971	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.712C>T; p.Q238*; 8:16164170-16164170	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Nonsense
c.712C>T; p.Q238*; 8:16164170-16164170	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.1068C>T; p.S356S; 8:16120572-16120572	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.371G>A; p.R124K; 8:16168717-16168717	skin	malignant_melanoma	Substitution - Missense
c.536C>T; p.S179F; 8:16168552-16168552	skin	malignant_melanoma	Substitution - Missense
c.311G>A; p.S104N; 8:16168777-16168777	skin	malignant_melanoma	Substitution - Missense
c.901C>T; p.P301S; 8:16150309-16150309	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.778G>A; p.E260K; 8:16164104-16164104	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.653G>A; p.R218H; 8:16164229-16164229	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.653G>A; p.R218H; 8:16164229-16164229	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.815A>C; p.Q272P; 8:16164067-16164067	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.209T>A; p.I70K; 8:16175195-16175195	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.88G>A; p.A30T; 8:16177901-16177901	skin	malignant_melanoma	Substitution - Missense
c.206G>T; p.G69V; 8:16175198-16175198	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1133G>A; p.R378H; 8:16120507-16120507	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1043C>T; p.T348M; 8:16120597-16120597	liver	carcinoma	Substitution - Missense
c.1133G>A; p.R378H; 8:16120507-16120507	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1104C>A; p.S368R; 8:16120536-16120536	urinary_tract; bladder	carcinoma	Substitution - Missense
c.101C>T; p.P34L; 8:16177888-16177888	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.862G>A; p.G288R; 8:16155100-16155100	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.845G>A; p.G282E; 8:16155117-16155117	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.808T>A; p.L270I; 8:16164074-16164074	skin	malignant_melanoma	Substitution - Missense
c.1292T>G; p.I431S; 8:16110149-16110149	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.690A>T; p.K230N; 8:16164192-16164192	skin	malignant_melanoma	Substitution - Missense
c.791C>A; p.T264N; 8:16164091-16164091	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.208A>C; p.I70L; 8:16175196-16175196	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.200T>C; p.L67P; 8:16175204-16175204	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.757G>A; p.D253N; 8:16164125-16164125	skin	malignant_melanoma	Substitution - Missense
c.354G>T; p.M118I; 8:16168734-16168734	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.949C>T; p.R317*; 8:16150261-16150261	skin	malignant_melanoma	Substitution - Nonsense
c.896T>A; p.I299K; 8:16155066-16155066	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation