Cancer metastasis database

Annotation category 5

Gene information

Gene ID 408
Symbol

ARRB1

Synonymous

ARB1|ARR1

Full name

arrestin, beta 1

Gene description

arrestin 2|beta-arrestin-1

Cytoband

11q13

Gene type

protein-coding

Synonymous

MIM:107940; HGNC:HGNC:711; Ensembl:ENSG00000137486; HPRD:00146; Vega:OTTHUMG00000165444

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.449delG; p.C150fs*50; 11:75281108-75281108

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.58G>A; p.V20I; 11:75287369-75287369

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.770_776+1delAGGCTGAG; p.?; 11:75276838-75276845

 skin; chestmalignant_melanomaUnknown

c.58G>A; p.V20I; 11:75287369-75287369

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.58G>A; p.V20I; 11:75287369-75287369

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - Missense

c.1180G>A; p.D394N; 11:75266216-75266216

 pancreascarcinomaSubstitution - Missense

c.998+7G>A; p.?; 11:75272888-75272888

 lungcarcinoma; squamous_cell_carcinomaUnknown

c.226C>T; p.R76C; 11:75283415-75283415

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.311T>C; p.L104P; 11:75283330-75283330

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.227G>A; p.R76H; 11:75283414-75283414

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1038C>T; p.P346P; 11:75268920-75268920

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.925G>A; p.G309S; 11:75272968-75272968

 skin; neckmalignant_melanomaSubstitution - Missense

c.975G>A; p.V325V; 11:75272918-75272918

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.774T>G; p.A258A; 11:75276841-75276841

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.257C>T; p.S86L; 11:75283384-75283384

 skinmalignant_melanomaSubstitution - Missense

c.861C>T; p.L287L; 11:75274127-75274127

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.170T>C; p.L57P; 11:75283471-75283471

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1008C>T; p.A336A; 11:75268950-75268950

 skinmalignant_melanomaSubstitution - coding silent

c.1059G>A; p.P353P; 11:75268899-75268899

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1073C>T; p.P358L; 11:75267700-75267700

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1073C>T; p.P358L; 11:75267700-75267700

 lungcarcinoma; bronchioloalveolar_adenocarcinomaSubstitution - Missense

c.1173G>T; p.M391I; 11:75266223-75266223

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1127A>T; p.D376V; 11:75266269-75266269

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.354+8A>G; p.?; 11:75283279-75283279

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; essential_thrombocythaemiaUnknown

c.421G>A; p.G141S; 11:75281136-75281136

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1085C>G; p.T362R; 11:75267688-75267688

 breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.1085C>G; p.T362R; 11:75267688-75267688

 breastcarcinoma; HER-positive_carcinomaSubstitution - Missense

c.392C>T; p.P131L; 11:75281984-75281984

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.470_472delAGA; p.K157delK; 11:75281085-75281087

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - In frame

c.874A>C; p.K292Q; 11:75274114-75274114

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1185G>T; p.K395N; 11:75266211-75266211

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.973delG; p.V325fs*1; 11:75272920-75272920

 lungcarcinoma; adenocarcinomaDeletion - Frameshift

c.1153C>T; p.R385C; 11:75266243-75266243

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.693C>G; p.I231M; 11:75277374-75277374

 breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.800C>T; p.T267M; 11:75274188-75274188

 ovarycarcinomaSubstitution - Missense

c.680C>T; p.T227M; 11:75277387-75277387

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.820C>T; p.L274L; 11:75274168-75274168

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.639C>T; p.P213P; 11:75277428-75277428

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.403G>A; p.D135N; 11:75281973-75281973

 skinmalignant_melanomaSubstitution - Missense

c.1086G>A; p.T362T; 11:75267687-75267687

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.231G>A; p.K77K; 11:75283410-75283410

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1085C>T; p.T362M; 11:75267688-75267688

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.152G>A; p.R51Q; 11:75284240-75284240

 bone; pelvisEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.184C>T; p.R62C; 11:75283457-75283457

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; mantle_cell_lymphomaSubstitution - Missense

c.517T>C; p.Y173H; 11:75278710-75278710

 livercarcinomaSubstitution - Missense

c.517T>C; p.Y173H; 11:75278710-75278710

 livercarcinomaSubstitution - Missense

c.1048G>A; p.E350K; 11:75268910-75268910

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.393G>A; p.P131P; 11:75281983-75281983

 kidneyother; neoplasmSubstitution - coding silent

c.1056C>A; p.P352P; 11:75268902-75268902

 livercarcinomaSubstitution - coding silent

c.854G>A; p.R285Q; 11:75274134-75274134

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1056C>A; p.P352P; 11:75268902-75268902

 livercarcinomaSubstitution - coding silent

c.893C>T; p.T298M; 11:75274095-75274095

 breastcarcinoma; ER-PR-positive_carcinomaSubstitution - Missense

c.189T>C; p.Y63Y; 11:75283452-75283452

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - coding silent

c.982G>T; p.V328L; 11:75272911-75272911

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.409G>A; p.G137R; 11:75281967-75281967

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.909C>T; p.S303S; 11:75274079-75274079

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.142C>T; p.L48F; 11:75284250-75284250

 breastcarcinomaSubstitution - Missense

c.935G>A; p.R312H; 11:75272958-75272958

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.188A>G; p.Y63C; 11:75283453-75283453

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1063C>T; p.R355W; 11:75268895-75268895

 thyroidcarcinomaSubstitution - Missense

c.1057C>T; p.P353S; 11:75268901-75268901

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1058C>T; p.P353L; 11:75268900-75268900

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.973G>A; p.V325M; 11:75272920-75272920

 skinmalignant_melanomaSubstitution - Missense

c.1002C>T; p.D334D; 11:75268956-75268956

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1002C>T; p.D334D; 11:75268956-75268956

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1161A>C; p.R387S; 11:75266235-75266235

 thyroidother; neoplasmSubstitution - Missense

c.436G>A; p.V146I; 11:75281121-75281121

 ovaryother; neoplasmSubstitution - Missense

c.942C>T; p.I314I; 11:75272951-75272951

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.493C>T; p.R165C; 11:75278734-75278734

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.681G>A; p.T227T; 11:75277386-75277386

 pituitary; craniopharyngeal_ductcraniopharyngioma; adamantinomatousSubstitution - coding silent

c.959C>A; p.S320Y; 11:75272934-75272934

 central_nervous_system; brainstemglioma; oligoastrocytoma_Grade_IIISubstitution - Missense