lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	3958
Symbol	LGALS3
Synonymous	CBP35\|GAL3\|GALBP\|GALIG\|L31\|LGALS2\|MAC2
Full name	lectin, galactoside-binding, soluble, 3
Gene description	35 kDa lectin\|IgE-binding protein\|MAC-2 antigen\|carbohydrate-binding protein 35\|galactose-specific lectin 3\|galectin-3\|laminin-binding protein\|lectin L-29
Cytoband	14q22.3
Gene type	protein-coding
Synonymous	MIM:153619; HGNC:HGNC:6563; Ensembl:ENSG00000131981; HPRD:01090; HPRD:17026; Vega:OTTHUMG00000171030

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.541T>C; p.W181R; 14:55142693-55142693	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.253G>A; p.G85S; 14:55138279-55138279	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.253G>A; p.G85S; 14:55138279-55138279	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.363T>C; p.P121P; 14:55140295-55140295	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.50C>A; p.P17Q; 14:55138076-55138076	thyroid	other; neoplasm	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	breast	carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	thyroid	other; neoplasm	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	thyroid	other; neoplasm	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302A>C; p.Y101S; 14:55138328-55138328	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.695G>A; p.S232N; 14:55145213-55145213	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.193G>A; p.G65R; 14:55138219-55138219	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.30G>A; p.A10A; 14:55138056-55138056	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.671G>A; p.R224Q; 14:55145189-55145189	liver	carcinoma	Substitution - Missense
c.671G>A; p.R224Q; 14:55145189-55145189	liver	carcinoma	Substitution - Missense
c.671G>A; p.R224Q; 14:55145189-55145189	liver	carcinoma	Substitution - Missense
c.139G>A; p.G47R; 14:55138165-55138165	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.211C>T; p.P71S; 14:55138237-55138237	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.18G>A; p.S6S; 14:55137391-55137391	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.629A>G; p.K210R; 14:55145147-55145147	prostate	carcinoma	Substitution - Missense
c.414G>A; p.V138V; 14:55140346-55140346	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.95G>A; p.G32E; 14:55138121-55138121	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.303C>T; p.Y101Y; 14:55138329-55138329	liver	carcinoma	Substitution - coding silent
c.303C>T; p.Y101Y; 14:55138329-55138329	liver	carcinoma	Substitution - coding silent
c.466G>T; p.A156S; 14:55142618-55142618	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.649C>T; p.H217Y; 14:55145167-55145167	breast	carcinoma	Substitution - Missense
c.135delC; p.Q48fs*67; 14:55138161-55138161	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.73G>A; p.A25T; 14:55138099-55138099	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.661T>C; p.Y221H; 14:55145179-55145179	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.18G>T; p.S6S; 14:55137391-55137391	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.606A>G; p.V202V; 14:55145124-55145124	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation