Cancer metastasis database

Annotation category 5

Gene information

Gene ID 2876
Symbol

GPX1

Synonymous

GPXD|GSHPX1

Full name

glutathione peroxidase 1

Gene description

GPx-1|GSHPx-1|cellular glutathione peroxidase

Cytoband

3p21.3

Gene type

protein-coding

Synonymous

MIM:138320; HGNC:HGNC:4553; Ensembl:ENSG00000233276; HPRD:11749; Vega:OTTHUMG00000156837

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.167A>C; p.Y56S; 3:49358112-49358112

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.445C>T; p.L149F; 3:49357555-49357555

 skinmalignant_melanomaSubstitution - Missense

c.33_38delGGCGGC; p.A12_A13delAA; 3:49358241-49358246

 breastcarcinomaDeletion - In frame

c.205C>A; p.R69R; 3:49358074-49358074

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.18A>G; p.L6L; 3:49358261-49358261

 thyroidother; neoplasmSubstitution - coding silent

c.336C>G; p.F112L; 3:49357664-49357664

 pancreascarcinomaSubstitution - Missense

c.524C>T; p.P175L; 3:49357476-49357476

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.599C>T; p.P200L; 3:49357401-49357401

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.415G>A; p.D139N; 3:49357585-49357585

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.489C>G; p.N163K; 3:49357511-49357511

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.486G>C; p.W162C; 3:49357514-49357514

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.380C>T; p.A127V; 3:49357620-49357620

 skinmalignant_melanomaSubstitution - Missense

c.451A>G; p.T151A; 3:49357549-49357549

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.109G>A; p.G37S; 3:49358170-49358170

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.468T>A; p.C156*; 3:49357532-49357532

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.461C>T; p.P154L; 3:49357539-49357539

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; mantle_cell_lymphomaSubstitution - Missense

c.437A>G; p.D146G; 3:49357563-49357563

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.576C>A; p.I192I; 3:49357424-49357424

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.24G>A; p.A8A; 3:49358255-49358255

 livercarcinomaSubstitution - coding silent

c.126C>A; p.I42I; 3:49358153-49358153

 thyroidcarcinoma; anaplastic_carcinomaSubstitution - coding silent

c.126C>A; p.I42I; 3:49358153-49358153

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.364_365insG; p.A122fs*44; 3:49357635-49357636

 large_intestine; caecumcarcinoma; adenocarcinomaInsertion - Frameshift

c.17T>G; p.L6R; 3:49358262-49358262

 thyroidother; neoplasmSubstitution - Missense

c.333C>T; p.L111L; 3:49357667-49357667

 skinmalignant_melanomaSubstitution - coding silent

c.260C>G; p.A87G; 3:49357740-49357740

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - Missense

c.230C>G; p.P77R; 3:49358049-49358049

 skinmalignant_melanomaSubstitution - Missense

c.230C>G; p.P77R; 3:49358049-49358049

 skinmalignant_melanomaSubstitution - Missense

c.230C>G; p.P77R; 3:49358049-49358049

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.230C>G; p.P77R; 3:49358049-49358049

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.230C>G; p.P77R; 3:49358049-49358049

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.230C>G; p.P77R; 3:49358049-49358049

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.230C>G; p.P77R; 3:49358049-49358049

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.230C>G; p.P77R; 3:49358049-49358049

 skinmalignant_melanomaSubstitution - Missense

c.230C>G; p.P77R; 3:49358049-49358049

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.230C>G; p.P77R; 3:49358049-49358049

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.230C>G; p.P77R; 3:49358049-49358049

 central_nervous_system; braingliomaSubstitution - Missense

c.230C>G; p.P77R; 3:49358049-49358049

 prostatecarcinoma; adenocarcinomaSubstitution - Missense