lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	23035
Symbol	PHLPP2
Synonymous	PHLPPL
Full name	PH domain and leucine rich repeat protein phosphatase 2
Gene description	PH domain leucine-rich repeat-containing protein phosphatase 2
Cytoband	16q22.2
Gene type	protein-coding
Synonymous	MIM:611066; HGNC:HGNC:29149; Ensembl:ENSG00000040199; HPRD:11118; Vega:OTTHUMG00000176867

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.1112C>T; p.S371F; 16:71678911-71678911	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1028A>C; p.N343T; 16:71679398-71679398	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1180G>A; p.D394N; 16:71678843-71678843	skin	malignant_melanoma	Substitution - Missense
c.2744C>T; p.S915F; 16:71652863-71652863	skin; scalp	malignant_melanoma	Substitution - Missense
c.1833C>T; p.S611S; 16:71664051-71664051	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.736-1G>A; p.?; 16:71681906-71681906	skin	malignant_melanoma	Unknown
c.280G>C; p.V94L; 16:71714516-71714516	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.305G>A; p.R102Q; 16:71702711-71702711	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1200A>G; p.G400G; 16:71678823-71678823	breast	carcinoma	Substitution - coding silent
c.3051G>A; p.A1017A; 16:71649811-71649811	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3540G>A; p.E1180E; 16:71649322-71649322	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2384G>T; p.R795I; 16:71656577-71656577	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3056G>A; p.S1019N; 16:71649806-71649806	breast	carcinoma	Substitution - Missense
c.192C>T; p.L64L; 16:71714604-71714604	skin	malignant_melanoma	Substitution - coding silent
c.3143C>T; p.T1048I; 16:71649719-71649719	skin	malignant_melanoma	Substitution - Missense
c.192C>T; p.L64L; 16:71714604-71714604	skin	malignant_melanoma	Substitution - coding silent
c.833A>G; p.N278S; 16:71681808-71681808	breast	carcinoma	Substitution - Missense
c.1925_1926delGG; p.G642fs*24; 16:71663958-71663959	breast	carcinoma	Deletion - Frameshift
c.3047T>C; p.L1016S; 16:71649815-71649815	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3047T>C; p.L1016S; 16:71649815-71649815	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.145A>G; p.T49A; 16:71714651-71714651	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.876C>T; p.L292L; 16:71681765-71681765	skin	malignant_melanoma	Substitution - coding silent
c.2532G>A; p.Q844Q; 16:71655293-71655293	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1225G>A; p.G409R; 16:71678798-71678798	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2844C>T; p.C948C; 16:71650018-71650018	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1014A>C; p.P338P; 16:71679412-71679412	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3777A>C; p.T1259T; 16:71649085-71649085	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.318C>T; p.I106I; 16:71702698-71702698	skin	malignant_melanoma	Substitution - coding silent
c.96T>G; p.C32W; 16:71714700-71714700	breast	carcinoma	Substitution - Missense
c.3002G>A; p.R1001H; 16:71649860-71649860	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3778G>T; p.E1260*; 16:71649084-71649084	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.3535C>T; p.L1179L; 16:71649327-71649327	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.3778G>T; p.E1260*; 16:71649084-71649084	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.3616C>T; p.R1206*; 16:71649246-71649246	pancreas	carcinoma	Substitution - Nonsense
c.3727G>A; p.G1243S; 16:71649135-71649135	skin	malignant_melanoma	Substitution - Missense
c.2697C>T; p.G899G; 16:71652910-71652910	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1116C>T; p.S372S; 16:71678907-71678907	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3006C>T; p.H1002H; 16:71649856-71649856	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1116C>T; p.S372S; 16:71678907-71678907	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1442C>T; p.S481F; 16:71676476-71676476	skin	malignant_melanoma	Substitution - Missense
c.1442C>T; p.S481F; 16:71676476-71676476	skin	malignant_melanoma	Substitution - Missense
c.2852G>A; p.R951Q; 16:71650010-71650010	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.31A>C; p.N11H; 16:71714765-71714765	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.624G>C; p.K208N; 16:71684587-71684587	urinary_tract; bladder	carcinoma	Substitution - Missense
c.793C>T; p.P265S; 16:71681848-71681848	skin	malignant_melanoma	Substitution - Missense
c.838C>T; p.R280*; 16:71681803-71681803	skin; trunk	malignant_melanoma	Substitution - Nonsense
c.564T>C; p.D188D; 16:71690564-71690564	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1242G>A; p.M414I; 16:71678781-71678781	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.2468G>A; p.R823Q; 16:71655357-71655357	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2576T>C; p.V859A; 16:71655249-71655249	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2576T>C; p.V859A; 16:71655249-71655249	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2486G>A; p.R829H; 16:71655339-71655339	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2858T>G; p.L953R; 16:71650004-71650004	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.439C>T; p.R147C; 16:71690689-71690689	skin	malignant_melanoma	Substitution - Missense
c.976G>A; p.E326K; 16:71679450-71679450	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.439C>T; p.R147C; 16:71690689-71690689	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2964G>T; p.W988C; 16:71649898-71649898	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3198_3199insC; p.A1068fs*6; 16:71649663-71649664	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Insertion - Frameshift
c.3260C>T; p.S1087L; 16:71649602-71649602	skin	malignant_melanoma	Substitution - Missense
c.1918C>T; p.L640L; 16:71663966-71663966	skin	malignant_melanoma	Substitution - coding silent
c.2881T>G; p.W961G; 16:71649981-71649981	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3966A>T; p.A1322A; 16:71648896-71648896	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2555T>G; p.F852C; 16:71655270-71655270	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.315_316GA>TT; p.Q105_I106>HF; 16:71702700-71702701	ovary	carcinoma; serous_carcinoma	Complex - compound substitution
c.1448_1449GG>AA; p.R483Q; 16:71676469-71676470	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3230C>A; p.A1077D; 16:71649632-71649632	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3318G>A; p.L1106L; 16:71649544-71649544	skin	malignant_melanoma	Substitution - coding silent
c.757A>T; p.T253S; 16:71681884-71681884	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1000T>C; p.F334L; 16:71679426-71679426	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2092G>A; p.A698T; 16:71658709-71658709	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1393C>T; p.L465L; 16:71676525-71676525	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1374C>T; p.S458S; 16:71676544-71676544	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1598G>A; p.S533N; 16:71669305-71669305	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3904C>T; p.R1302W; 16:71648958-71648958	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3196A>G; p.K1066E; 16:71649666-71649666	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.958G>A; p.E320K; 16:71679468-71679468	skin	malignant_melanoma	Substitution - Missense
c.919T>A; p.S307T; 16:71679507-71679507	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1330G>A; p.V444M; 16:71676588-71676588	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.648C>T; p.F216F; 16:71684563-71684563	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1392G>T; p.Q464H; 16:71676526-71676526	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1505G>T; p.S502I; 16:71672289-71672289	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1666G>T; p.G556*; 16:71667296-71667296	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2585G>T; p.R862M; 16:71655240-71655240	breast	carcinoma	Substitution - Missense
c.3485G>A; p.G1162D; 16:71649377-71649377	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2170G>T; p.D724Y; 16:71658342-71658342	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.20G>T; p.R7I; 16:71714776-71714776	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1531C>A; p.R511R; 16:71672263-71672263	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - coding silent
c.1260G>T; p.V420V; 16:71678763-71678763	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.798G>A; p.E266E; 16:71681843-71681843	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1471A>T; p.R491W; 16:71676447-71676447	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1770C>G; p.F590L; 16:71667192-71667192	pancreas	carcinoma	Substitution - Missense
c.960G>T; p.E320D; 16:71679466-71679466	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1532G>C; p.R511P; 16:71672262-71672262	skin	malignant_melanoma	Substitution - Missense
c.1433G>T; p.S478I; 16:71676485-71676485	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.479G>A; p.R160H; 16:71690649-71690649	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3447T>C; p.S1149S; 16:71649415-71649415	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1712C>T; p.P571L; 16:71667250-71667250	skin	malignant_melanoma	Substitution - Missense
c.3063C>A; p.G1021G; 16:71649799-71649799	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1509G>T; p.L503L; 16:71672285-71672285	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.3063C>A; p.G1021G; 16:71649799-71649799	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2479C>T; p.L827F; 16:71655346-71655346	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1127C>T; p.S376F; 16:71678896-71678896	breast	carcinoma	Substitution - Missense
c.2928A>C; p.Q976H; 16:71649934-71649934	liver	carcinoma	Substitution - Missense
c.2079G>A; p.L693L; 16:71658722-71658722	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2928A>C; p.Q976H; 16:71649934-71649934	liver	carcinoma	Substitution - Missense
c.3946_3947CC>GT; p.P1316V; 16:71648915-71648916	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2815G>T; p.E939*; 16:71652792-71652792	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2117T>C; p.F706S; 16:71658684-71658684	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3915T>C; p.P1305P; 16:71648947-71648947	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2426C>T; p.A809V; 16:71655399-71655399	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2467C>T; p.R823*; 16:71655358-71655358	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3198G>C; p.K1066N; 16:71649664-71649664	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2585+1G>T; p.?; 16:71655239-71655239	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1224A>C; p.L408F; 16:71678799-71678799	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1174A>G; p.M392V; 16:71678849-71678849	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1623C>T; p.P541P; 16:71669280-71669280	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1623C>T; p.P541P; 16:71669280-71669280	pancreas	carcinoma	Substitution - coding silent
c.1648C>T; p.L550F; 16:71667314-71667314	breast	carcinoma	Substitution - Missense
c.2942T>A; p.I981N; 16:71649920-71649920	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3462C>T; p.P1154P; 16:71649400-71649400	skin	malignant_melanoma	Substitution - coding silent
c.1265T>G; p.L422*; 16:71678758-71678758	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3964G>T; p.A1322S; 16:71648898-71648898	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3692C>T; p.S1231F; 16:71649170-71649170	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1772C>T; p.S591F; 16:71667190-71667190	skin	malignant_melanoma	Substitution - Missense
c.639C>T; p.S213S; 16:71684572-71684572	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1261G>A; p.D421N; 16:71678762-71678762	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3156T>C; p.P1052P; 16:71649706-71649706	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1140T>C; p.F380F; 16:71678883-71678883	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3762C>T; p.L1254L; 16:71649100-71649100	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1140T>C; p.F380F; 16:71678883-71678883	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.2752T>G; p.F918V; 16:71652855-71652855	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2912C>G; p.T971S; 16:71649950-71649950	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2443G>T; p.V815L; 16:71655382-71655382	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.2493G>A; p.L831L; 16:71655332-71655332	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2751C>A; p.V917V; 16:71652856-71652856	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.64G>A; p.D22N; 16:71714732-71714732	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3378_3399del22; p.G1127fs*26; 16:71649463-71649484	skin; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.679C>T; p.H227Y; 16:71684532-71684532	NS	malignant_melanoma	Substitution - Missense
c.679C>T; p.H227Y; 16:71684532-71684532	NS	malignant_melanoma	Substitution - Missense
c.1115C>A; p.S372Y; 16:71678908-71678908	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.547G>A; p.V183I; 16:71690581-71690581	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.514C>T; p.R172C; 16:71690614-71690614	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2914C>T; p.P972S; 16:71649948-71649948	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.629G>T; p.R210L; 16:71684582-71684582	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.3199_3200delCC; p.P1067fs*6; 16:71649662-71649663	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.2501C>T; p.T834M; 16:71655324-71655324	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3868G>C; p.E1290Q; 16:71648994-71648994	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2284A>G; p.I762V; 16:71656677-71656677	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.478C>T; p.R160C; 16:71690650-71690650	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2836G>T; p.V946L; 16:71650026-71650026	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2343A>G; p.S781S; 16:71656618-71656618	skin	malignant_melanoma	Substitution - coding silent
c.3200_3201insC; p.A1068fs*6; 16:71649661-71649662	breast	carcinoma	Insertion - Frameshift
c.223G>T; p.E75*; 16:71714573-71714573	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1448G>A; p.R483Q; 16:71676470-71676470	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3197A>T; p.K1066M; 16:71649665-71649665	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2618C>T; p.S873F; 16:71652989-71652989	skin	malignant_melanoma	Substitution - Missense
c.1010T>C; p.L337P; 16:71679416-71679416	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.158C>T; p.S53F; 16:71714638-71714638	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3339G>A; p.R1113R; 16:71649523-71649523	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.690C>T; p.F230F; 16:71684521-71684521	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2485C>T; p.R829C; 16:71655340-71655340	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.3108T>C; p.G1036G; 16:71649754-71649754	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3561G>A; p.E1187E; 16:71649301-71649301	skin	malignant_melanoma	Substitution - coding silent
c.3460C>A; p.P1154T; 16:71649402-71649402	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2053A>G; p.T685A; 16:71658748-71658748	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3529A>G; p.R1177G; 16:71649333-71649333	thyroid	carcinoma	Substitution - Missense
c.572C>G; p.T191S; 16:71690556-71690556	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2119C>A; p.P707T; 16:71658682-71658682	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.274G>C; p.D92H; 16:71714522-71714522	breast	carcinoma	Substitution - Missense
c.3335C>T; p.P1112L; 16:71649527-71649527	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.38G>A; p.R13K; 16:71714758-71714758	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3940G>A; p.E1314K; 16:71648922-71648922	breast	carcinoma	Substitution - Missense
c.1532G>T; p.R511L; 16:71672262-71672262	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.3969A>G; p.L1323L; 16:71648893-71648893	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3969A>G; p.L1323L; 16:71648893-71648893	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.2377G>T; p.G793W; 16:71656584-71656584	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3505G>A; p.V1169I; 16:71649357-71649357	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2660C>A; p.P887Q; 16:71652947-71652947	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2024T>C; p.L675P; 16:71658777-71658777	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3566C>A; p.S1189Y; 16:71649296-71649296	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3566C>A; p.S1189Y; 16:71649296-71649296	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.193G>A; p.V65I; 16:71714603-71714603	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3217A>G; p.S1073G; 16:71649645-71649645	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2677T>C; p.L893L; 16:71652930-71652930	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3617G>A; p.R1206Q; 16:71649245-71649245	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2155G>A; p.D719N; 16:71658357-71658357	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1527C>G; p.L509L; 16:71672267-71672267	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3083C>T; p.A1028V; 16:71649779-71649779	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3083C>T; p.A1028V; 16:71649779-71649779	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1527C>G; p.L509L; 16:71672267-71672267	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.1577A>C; p.K526T; 16:71669326-71669326	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1577A>C; p.K526T; 16:71669326-71669326	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.609G>T; p.K203N; 16:71690519-71690519	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.666_667insA; p.A223fs*44; 16:71684544-71684545	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.3957C>T; p.F1319F; 16:71648905-71648905	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3223G>A; p.G1075R; 16:71649639-71649639	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1991T>C; p.L664P; 16:71658810-71658810	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1087G>T; p.E363*; 16:71678936-71678936	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1184G>A; p.R395K; 16:71678839-71678839	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3160G>T; p.G1054*; 16:71649702-71649702	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.304C>T; p.R102*; 16:71702712-71702712	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3683A>G; p.K1228R; 16:71649179-71649179	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1271T>C; p.M424T; 16:71676647-71676647	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2434G>A; p.V812M; 16:71655391-71655391	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1028A>G; p.N343S; 16:71679398-71679398	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.558G>T; p.V186V; 16:71690570-71690570	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1461C>T; p.A487A; 16:71676457-71676457	skin	malignant_melanoma	Substitution - coding silent
c.2454G>T; p.M818I; 16:71655371-71655371	liver	carcinoma	Substitution - Missense
c.2606A>G; p.Q869R; 16:71653001-71653001	pancreas	carcinoid-endocrine_tumour	Substitution - Missense
c.789G>C; p.E263D; 16:71681852-71681852	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1734G>T; p.Q578H; 16:71667228-71667228	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1359C>T; p.D453D; 16:71676559-71676559	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1359C>T; p.D453D; 16:71676559-71676559	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1359C>T; p.D453D; 16:71676559-71676559	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.3282_3283insG; p.S1095fs*5; 16:71649579-71649580	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.754A>C; p.S252R; 16:71681887-71681887	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.783C>T; p.L261L; 16:71681858-71681858	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.754A>C; p.S252R; 16:71681887-71681887	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3055A>G; p.S1019G; 16:71649807-71649807	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.3055A>G; p.S1019G; 16:71649807-71649807	pancreas	carcinoma	Substitution - Missense
c.1716C>G; p.L572L; 16:71667246-71667246	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.534T>C; p.G178G; 16:71690594-71690594	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation