Cancer metastasis database

Annotation category 5

Gene information

Gene ID 1890
Symbol

TYMP

Synonymous

ECGF|ECGF1|MEDPS1|MNGIE|MTDPS1|PDECGF|TP|hPD-ECGF

Full name

thymidine phosphorylase

Gene description

gliostatin|tdRPase

Cytoband

22q13.33

Gene type

protein-coding

Synonymous

MIM:131222; HGNC:HGNC:3148; Ensembl:ENSG00000025708; HPRD:08833; Vega:OTTHUMG00000150249

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.525G>A; p.V175V; 22:50527709-50527709

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.326G>C; p.R109P; 22:50529227-50529227

 central_nervous_system; brainglioma; astrocytoma_Grade_IISubstitution - Missense

c.293C>G; p.S98W; 22:50529260-50529260

 breastcarcinomaSubstitution - Missense

c.158A>G; p.D53G; 22:50529552-50529552

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.714G>T; p.G238G; 22:50527216-50527216

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.186G>A; p.V62V; 22:50529524-50529524

 breastcarcinomaSubstitution - coding silent

c.271C>G; p.L91V; 22:50529282-50529282

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1393G>A; p.A465T; 22:50525826-50525826

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.383T>A; p.V128D; 22:50529170-50529170

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.546C>T; p.C182C; 22:50527688-50527688

 breastcarcinomaSubstitution - coding silent

c.1439C>A; p.P480Q; 22:50525780-50525780

 livercarcinomaSubstitution - Missense

c.236G>T; p.R79L; 22:50529317-50529317

 thyroidcarcinomaSubstitution - Missense

c.351C>T; p.S117S; 22:50529202-50529202

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.151G>A; p.E51K; 22:50529559-50529559

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.151G>A; p.E51K; 22:50529559-50529559

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.561G>C; p.Q187H; 22:50527673-50527673

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.178G>A; p.A60T; 22:50529532-50529532

 salivary_glandcarcinoma; adenoid_cystic_carcinomaSubstitution - Missense

c.743C>A; p.A248D; 22:50527187-50527187

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.617C>T; p.A206V; 22:50527617-50527617

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.743C>A; p.A248D; 22:50527187-50527187

 livercarcinomaSubstitution - Missense

c.242G>A; p.R81Q; 22:50529311-50529311

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.908G>A; p.R303K; 22:50526596-50526596

 thyroidother; neoplasmSubstitution - Missense

c.249G>T; p.M83I; 22:50529304-50529304

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.156G>A; p.A52A; 22:50529554-50529554

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.156G>A; p.A52A; 22:50529554-50529554

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.241C>T; p.R81W; 22:50529312-50529312

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.241C>T; p.R81W; 22:50529312-50529312

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.524T>C; p.V175A; 22:50527710-50527710

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.236G>A; p.R79Q; 22:50529317-50529317

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.49G>A; p.D17N; 22:50529661-50529661

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.49G>A; p.D17N; 22:50529661-50529661

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.49G>A; p.D17N; 22:50529661-50529661

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.514C>T; p.Q172*; 22:50528514-50528514

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1429G>C; p.V477L; 22:50525790-50525790

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.387C>T; p.L129L; 22:50529166-50529166

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.426G>A; p.M142I; 22:50528602-50528602

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.684C>T; p.S228S; 22:50527246-50527246

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.333G>C; p.Q111H; 22:50529220-50529220

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.54C>A; p.F18L; 22:50529656-50529656

 livercarcinomaSubstitution - Missense

c.54C>A; p.F18L; 22:50529656-50529656

 livercarcinomaSubstitution - Missense

c.1150C>T; p.P384S; 22:50526255-50526255

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1150C>T; p.P384S; 22:50526255-50526255

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1150C>T; p.P384S; 22:50526255-50526255

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.126G>T; p.M42I; 22:50529584-50529584

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1043C>A; p.A348E; 22:50526362-50526362

 pancreascarcinomaSubstitution - Missense

c.646G>T; p.A216S; 22:50527588-50527588

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.510A>T; p.P170P; 22:50528518-50528518

 lungcarcinoid-endocrine_tumour; typicalSubstitution - coding silent

c.197C>T; p.A66V; 22:50529513-50529513

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.210G>T; p.Q70H; 22:50529500-50529500

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.223C>T; p.L75L; 22:50529330-50529330

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1111C>T; p.L371L; 22:50526294-50526294

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.568C>T; p.Q190*; 22:50527666-50527666

 pancreascarcinomaSubstitution - Nonsense

c.586G>A; p.G196R; 22:50527648-50527648

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.326G>A; p.R109H; 22:50529227-50529227

 central_nervous_system; braingliomaSubstitution - Missense

c.230C>T; p.A77V; 22:50529323-50529323

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.247A>G; p.M83V; 22:50529306-50529306

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.23G>A; p.G8E; 22:50529687-50529687

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.446G>A; p.G149E; 22:50528582-50528582

 prostatecarcinomaSubstitution - Missense

c.23G>C; p.G8A; 22:50529687-50529687

 lungcarcinoma; adenocarcinomaSubstitution - Missense