lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	1230
Symbol	CCR1
Synonymous	CD191\|CKR-1\|CKR1\|CMKBR1\|HM145\|MIP1aR\|SCYAR1
Full name	chemokine (C-C motif) receptor 1
Gene description	C-C CKR-1\|C-C chemokine receptor type 1\|CC-CKR-1\|CCR-1\|LD78 receptor\|MIP-1alpha-R\|RANTES receptor\|RANTES-R\|macrophage inflammatory protein 1-alpha receptor
Cytoband	3p21
Gene type	protein-coding
Synonymous	MIM:601159; HGNC:HGNC:1602; Ensembl:ENSG00000163823; HPRD:03101; Vega:OTTHUMG00000133451

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.1062G>A; p.G354G; 3:46203252-46203252	skin	malignant_melanoma	Substitution - coding silent
c.415G>A; p.V139M; 3:46203899-46203899	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.68C>T; p.P23L; 3:46204246-46204246	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.386T>A; p.I129N; 3:46203928-46203928	breast	carcinoma	Substitution - Missense
c.1030C>T; p.P344S; 3:46203284-46203284	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.69G>T; p.P23P; 3:46204245-46204245	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.35C>A; p.T12K; 3:46204279-46204279	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.801C>T; p.F267F; 3:46203513-46203513	skin	malignant_melanoma	Substitution - coding silent
c.807C>A; p.F269L; 3:46203507-46203507	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.916G>A; p.E306K; 3:46203398-46203398	breast	carcinoma	Substitution - Missense
c.563C>T; p.P188L; 3:46203751-46203751	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.1052T>C; p.L351P; 3:46203262-46203262	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.497T>C; p.M166T; 3:46203817-46203817	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.909C>T; p.F303F; 3:46203405-46203405	skin	malignant_melanoma	Substitution - coding silent
c.910G>A; p.V304I; 3:46203404-46203404	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.342C>A; p.Y114*; 3:46203972-46203972	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3G>A; p.M1I; 3:46204311-46204311	skin	malignant_melanoma	Substitution - Missense
c.868G>A; p.A290T; 3:46203446-46203446	peritoneum; appendix	other; pseudomyxoma_peritonei	Substitution - Missense
c.529G>A; p.E177K; 3:46203785-46203785	skin	malignant_melanoma	Substitution - Missense
c.529G>A; p.E177K; 3:46203785-46203785	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.529G>A; p.E177K; 3:46203785-46203785	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1041G>A; p.G347G; 3:46203273-46203273	skin	malignant_melanoma	Substitution - coding silent
c.845C>T; p.A282V; 3:46203469-46203469	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.845C>T; p.A282V; 3:46203469-46203469	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.427C>T; p.R143W; 3:46203887-46203887	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.785C>A; p.S262Y; 3:46203529-46203529	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.1046A>G; p.H349R; 3:46203268-46203268	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.785C>A; p.S262Y; 3:46203529-46203529	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.457A>T; p.T153S; 3:46203857-46203857	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.357C>T; p.S119S; 3:46203957-46203957	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.585G>A; p.W195*; 3:46203729-46203729	skin	malignant_melanoma	Substitution - Nonsense
c.585G>A; p.W195*; 3:46203729-46203729	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.325C>A; p.L109I; 3:46203989-46203989	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.445T>A; p.F149I; 3:46203869-46203869	skin	malignant_melanoma	Substitution - Missense
c.1053C>A; p.L351L; 3:46203261-46203261	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1052T>G; p.L351R; 3:46203262-46203262	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.867C>T; p.I289I; 3:46203447-46203447	skin	malignant_melanoma	Substitution - coding silent
c.867C>T; p.I289I; 3:46203447-46203447	skin	malignant_melanoma	Substitution - coding silent
c.111G>A; p.L37L; 3:46204203-46204203	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.844G>A; p.A282T; 3:46203470-46203470	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.818G>T; p.C273F; 3:46203496-46203496	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.93C>T; p.A31A; 3:46204221-46204221	skin	malignant_melanoma	Substitution - coding silent
c.577C>T; p.R193*; 3:46203737-46203737	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.200delA; p.N67fs*2; 3:46204114-46204114	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.22G>A; p.E8K; 3:46204292-46204292	skin	malignant_melanoma	Substitution - Missense
c.735G>A; p.M245I; 3:46203579-46203579	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.891C>T; p.N297N; 3:46203423-46203423	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.384G>A; p.T128T; 3:46203930-46203930	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.384G>A; p.T128T; 3:46203930-46203930	skin	malignant_melanoma	Substitution - coding silent
c.93C>A; p.A31A; 3:46204221-46204221	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1051C>T; p.L351F; 3:46203263-46203263	skin	malignant_melanoma	Substitution - Missense
c.766A>T; p.N256Y; 3:46203548-46203548	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.408C>T; p.V136V; 3:46203906-46203906	skin	malignant_melanoma	Substitution - coding silent
c.949C>T; p.H317Y; 3:46203365-46203365	skin	malignant_melanoma	Substitution - Missense
c.568G>A; p.E190K; 3:46203746-46203746	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.362T>A; p.I121N; 3:46203952-46203952	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.149T>C; p.V50A; 3:46204165-46204165	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.857C>T; p.T286M; 3:46203457-46203457	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.262C>T; p.P88S; 3:46204052-46204052	skin	malignant_melanoma	Substitution - Missense
c.603G>A; p.L201L; 3:46203711-46203711	skin	malignant_melanoma	Substitution - coding silent
c.358G>A; p.E120K; 3:46203956-46203956	skin	malignant_melanoma	Substitution - Missense
c.154A>C; p.N52H; 3:46204160-46204160	liver	carcinoma	Substitution - Missense
c.154A>C; p.N52H; 3:46204160-46204160	liver	carcinoma	Substitution - Missense
c.474G>A; p.W158*; 3:46203840-46203840	prostate	adenoma	Substitution - Nonsense
c.219C>T; p.L73L; 3:46204095-46204095	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.303delT; p.F101fs*27; 3:46204011-46204011	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.572G>A; p.S191N; 3:46203742-46203742	urinary_tract; bladder	carcinoma	Substitution - Missense
c.545C>T; p.T182I; 3:46203769-46203769	skin	malignant_melanoma	Substitution - Missense
c.677T>C; p.L226P; 3:46203637-46203637	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.685C>T; p.R229*; 3:46203629-46203629	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Nonsense
c.985C>T; p.P329S; 3:46203329-46203329	skin	malignant_melanoma	Substitution - Missense
c.748C>T; p.L250F; 3:46203566-46203566	skin	malignant_melanoma	Substitution - Missense
c.383C>T; p.T128M; 3:46203931-46203931	pancreas	NS	Substitution - Missense
c.363C>A; p.I121I; 3:46203951-46203951	breast	carcinoma	Substitution - coding silent
c.406G>A; p.V136I; 3:46203908-46203908	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.273C>T; p.I91I; 3:46204041-46204041	skin	malignant_melanoma	Substitution - coding silent
c.101C>T; p.A34V; 3:46204213-46204213	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4G>A; p.E2K; 3:46204310-46204310	skin	malignant_melanoma	Substitution - Missense
c.567C>T; p.H189H; 3:46203747-46203747	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.672G>A; p.K224K; 3:46203642-46203642	skin	malignant_melanoma	Substitution - coding silent
c.672G>A; p.K224K; 3:46203642-46203642	skin	malignant_melanoma	Substitution - coding silent
c.398T>G; p.L133R; 3:46203916-46203916	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.438C>T; p.T146T; 3:46203876-46203876	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.544A>C; p.T182P; 3:46203770-46203770	breast	carcinoma	Substitution - Missense
c.231C>T; p.A77A; 3:46204083-46204083	skin; trunk	malignant_melanoma; nodular	Substitution - coding silent
c.714C>T; p.V238V; 3:46203600-46203600	skin	malignant_melanoma	Substitution - coding silent
c.1032C>A; p.P344P; 3:46203282-46203282	pancreas	carcinoma	Substitution - coding silent
c.1032C>A; p.P344P; 3:46203282-46203282	pancreas	carcinoma	Substitution - coding silent
c.412G>A; p.A138T; 3:46203902-46203902	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.412G>A; p.A138T; 3:46203902-46203902	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation