Cancer metastasis database

Annotation category 5

Gene information

Gene ID 11197
Symbol

WIF1

Synonymous

WIF-1

Full name

WNT inhibitory factor 1

Gene description

wnt inhibitory factor 1

Cytoband

12q14.3

Gene type

protein-coding

Synonymous

MIM:605186; HGNC:HGNC:18081; Ensembl:ENSG00000156076; HPRD:05541; Vega:OTTHUMG00000168832

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.552C>T; p.G184G; 12:65067777-65067777

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.931G>A; p.E311K; 12:65055205-65055205

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.559C>T; p.R187*; 12:65067770-65067770

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1098C>A; p.A366A; 12:65051391-65051391

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.708C>A; p.F236L; 12:65066663-65066663

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.482G>A; p.G161D; 12:65068820-65068820

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.762G>A; p.G254G; 12:65062545-65062545

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.313T>C; p.S105P; 12:65077830-65077830

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.731-3C>A; p.?; 12:65062579-65062579

 oesophaguscarcinoma; adenocarcinomaUnknown

c.439G>T; p.V147L; 12:65068863-65068863

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.288+1G>C; p.?; 12:65120416-65120416

 ovarycarcinoma; serous_carcinomaUnknown

c.374G>A; p.G125E; 12:65077769-65077769

 skinmalignant_melanomaSubstitution - Missense

c.1024G>A; p.E342K; 12:65051465-65051465

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1024G>A; p.E342K; 12:65051465-65051465

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1091A>G; p.K364R; 12:65051398-65051398

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.163A>G; p.I55V; 12:65120542-65120542

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.242C>T; p.P81L; 12:65120463-65120463

 skinmalignant_melanomaSubstitution - Missense

c.591C>G; p.I197M; 12:65067738-65067738

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.304G>A; p.E102K; 12:65077839-65077839

 skinmalignant_melanomaSubstitution - Missense

c.637C>A; p.L213I; 12:65066734-65066734

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.21C>T; p.F7F; 12:65121171-65121171

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.215A>T; p.K72I; 12:65120490-65120490

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.997C>A; p.H333N; 12:65055139-65055139

 skinmalignant_melanomaSubstitution - Missense

c.446C>A; p.A149E; 12:65068856-65068856

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1078A>G; p.T360A; 12:65051411-65051411

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.602C>T; p.P201L; 12:65067727-65067727

 skinmalignant_melanomaSubstitution - Missense

c.847C>A; p.R283R; 12:65056106-65056106

 livercarcinomaSubstitution - coding silent

c.847C>A; p.R283R; 12:65056106-65056106

 livercarcinomaSubstitution - coding silent

c.896G>T; p.G299V; 12:65056057-65056057

 livercarcinomaSubstitution - Missense

c.820G>A; p.E274K; 12:65062487-65062487

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.204T>C; p.H68H; 12:65120501-65120501

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.587G>A; p.R196H; 12:65067742-65067742

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.587G>A; p.R196H; 12:65067742-65067742

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1124C>T; p.S375F; 12:65051365-65051365

 livercarcinomaSubstitution - Missense

c.1124C>T; p.S375F; 12:65051365-65051365

 livercarcinomaSubstitution - Missense

c.1106G>C; p.R369P; 12:65051383-65051383

 lung; middle_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.680C>T; p.P227L; 12:65066691-65066691

 skinmalignant_melanomaSubstitution - Missense

c.1059C>T; p.G353G; 12:65051430-65051430

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.996G>A; p.W332*; 12:65055140-65055140

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.397+1G>A; p.?; 12:65077745-65077745

 ovarycarcinoma; serous_carcinomaUnknown

c.1004G>A; p.R335K; 12:65055132-65055132

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.320G>A; p.R107H; 12:65077823-65077823

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.546C>A; p.C182*; 12:65067783-65067783

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.704G>A; p.G235E; 12:65066667-65066667

 skin; shouldermalignant_melanomaSubstitution - Missense

c.634+1G>A; p.?; 12:65067694-65067694

 lungcarcinoma; squamous_cell_carcinomaUnknown

c.895G>T; p.G299C; 12:65056058-65056058

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.560G>A; p.R187Q; 12:65067769-65067769

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.294A>G; p.E98E; 12:65077849-65077849

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1133T>G; p.I378S; 12:65051356-65051356

 lungcarcinoma; non_small_cell_carcinomaSubstitution - Missense

c.560G>A; p.R187Q; 12:65067769-65067769

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.650G>A; p.R217Q; 12:65066721-65066721

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.255T>C; p.H85H; 12:65120450-65120450

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.398-2A>T; p.?; 12:65068906-65068906

 kidneycarcinoma; clear_cell_renal_cell_carcinomaUnknown

c.398-2A>T; p.?; 12:65068906-65068906

 kidneycarcinoma; clear_cell_renal_cell_carcinomaUnknown

c.398-2A>T; p.?; 12:65068906-65068906

 kidneycarcinoma; clear_cell_renal_cell_carcinomaUnknown

c.786T>C; p.C262C; 12:65062521-65062521

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.649C>T; p.R217*; 12:65066722-65066722

 central_nervous_system; braingliomaSubstitution - Nonsense

c.565G>A; p.G189R; 12:65067764-65067764

 skinmalignant_melanomaSubstitution - Missense

c.735C>T; p.N245N; 12:65062572-65062572

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.749G>C; p.C250S; 12:65062558-65062558

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.725A>G; p.D242G; 12:65066646-65066646

 central_nervous_system; braingliomaSubstitution - Missense

c.215A>G; p.K72R; 12:65120490-65120490

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.244G>C; p.V82L; 12:65120461-65120461

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.244G>C; p.V82L; 12:65120461-65120461

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.522T>G; p.F174L; 12:65068780-65068780

 skinmalignant_melanomaSubstitution - Missense

c.1116A>G; p.P372P; 12:65051373-65051373

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.250A>G; p.I84V; 12:65120455-65120455

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.309C>A; p.F103L; 12:65077834-65077834

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.854G>A; p.G285E; 12:65056099-65056099

 skinmalignant_melanomaSubstitution - Missense

c.929G>A; p.C310Y; 12:65055207-65055207

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.319C>T; p.R107C; 12:65077824-65077824

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.432G>A; p.Q144Q; 12:65068870-65068870

 skinmalignant_melanomaSubstitution - coding silent

c.520T>C; p.F174L; 12:65068782-65068782

 central_nervous_system; brainglioma; astrocytoma_Grade_IISubstitution - Missense

c.805G>C; p.E269Q; 12:65062502-65062502

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.922C>T; p.P308S; 12:65056031-65056031

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.547C>A; p.P183T; 12:65067782-65067782

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.547C>A; p.P183T; 12:65067782-65067782

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.647C>T; p.P216L; 12:65066724-65066724

 skinmalignant_melanomaSubstitution - Missense

c.693C>G; p.I231M; 12:65066678-65066678

 breastcarcinomaSubstitution - Missense

c.154G>A; p.E52K; 12:65120551-65120551

 breastcarcinomaSubstitution - Missense

c.642T>G; p.C214W; 12:65066729-65066729

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.356T>G; p.V119G; 12:65077787-65077787

 skinmalignant_melanomaSubstitution - Missense

c.323C>T; p.S108F; 12:65077820-65077820

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.415C>T; p.P139S; 12:65068887-65068887

 skinmalignant_melanomaSubstitution - Missense

c.805G>A; p.E269K; 12:65062502-65062502

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense