| Gene ID | 11065 |
| Symbol | UBE2C |
| Synonymous | UBCH10|dJ447F3.2 |
| Full name | ubiquitin-conjugating enzyme E2C |
| Gene description | cyclin-selective ubiquitin carrier protein|mitotic-specific ubiquitin-conjugating enzyme|ubiquitin-conjugating enzyme E2 C|ubiquitin-protein ligase C |
| Cytoband | 20q13.12 |
| Gene type | protein-coding |
| Synonymous | MIM:605574; HGNC:HGNC:15937; Ensembl:ENSG00000175063; HPRD:05717; Vega:OTTHUMG00000033038 |
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.294C>T; p.F98F; 20:45815618-45815618 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.511T>C; p.S171P; 20:45816738-45816738 |
liver | carcinoma | Substitution - Missense |
c.387G>T; p.R129S; 20:45815711-45815711 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.420A>G; p.G140G; 20:45815744-45815744 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - coding silent |
c.216+1G>C; p.?; 20:45814471-45814471 |
skin; extremity | malignant_melanoma | Unknown |
c.482-1G>C; p.?; 20:45816708-45816708 |
large_intestine; rectum | carcinoma; adenocarcinoma | Unknown |
c.246G>A; p.S82S; 20:45815570-45815570 |
upper_aerodigestive_tract; mouth | carcinoma | Substitution - coding silent |
c.246G>A; p.S82S; 20:45815570-45815570 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.246G>A; p.S82S; 20:45815570-45815570 |
upper_aerodigestive_tract; mouth | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.501A>G; p.Q167Q; 20:45816728-45816728 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.358G>T; p.E120*; 20:45815682-45815682 |
liver | carcinoma | Substitution - Nonsense |
c.217-1G>A; p.?; 20:45815540-45815540 |
lung | carcinoma; adenocarcinoma | Unknown |
c.279G>A; p.A93A; 20:45815603-45815603 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.123C>A; p.T41T; 20:45813458-45813458 |
lung | carcinoma; adenocarcinoma | Substitution - coding silent |
c.159C>T; p.F53F; 20:45814413-45814413 |
skin | malignant_melanoma | Substitution - coding silent |
c.299C>T; p.T100M; 20:45815623-45815623 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.474C>T; p.N158N; 20:45815906-45815906 |
skin | malignant_melanoma | Substitution - coding silent |
c.473A>C; p.N158T; 20:45815905-45815905 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.352C>T; p.L118L; 20:45815676-45815676 |
skin | malignant_melanoma | Substitution - coding silent |
c.300G>A; p.T100T; 20:45815624-45815624 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.374T>C; p.L125P; 20:45815698-45815698 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.14_15insC; p.R6fs*7; 20:45812709-45812710 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm; acute_myeloid_leukaemia | Insertion - Frameshift |
c.14_15insC; p.R6fs*7; 20:45812709-45812710 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm; acute_myeloid_leukaemia | Insertion - Frameshift |
c.459C>A; p.A153A; 20:45815891-45815891 |
prostate | adenoma | Substitution - coding silent |
c.70delG; p.G25fs*15; 20:45812765-45812765 |
autonomic_ganglia | neuroblastoma | Deletion - Frameshift |
c.399C>A; p.L133L; 20:45815723-45815723 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.102-2A>G; p.?; 20:45813435-45813435 |
urinary_tract; bladder | carcinoma | Unknown |
c.112G>C; p.E38Q; 20:45813447-45813447 |
thyroid | other; neoplasm | Substitution - Missense |
c.105A>G; p.L35L; 20:45813440-45813440 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.387G>A; p.R129R; 20:45815711-45815711 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - coding silent |