| Gene ID | 3667 |
| Symbol | IRS1 |
| Synonymous | HIRS-1 |
| Full name | insulin receptor substrate 1 |
| Gene description | IRS-1 |
| Cytoband | 2q36 |
| Gene type | protein-coding |
| Synonymous | MIM:147545; HGNC:HGNC:6125; Ensembl:ENSG00000169047; HPRD:00943; Vega:OTTHUMG00000133179 |
Pathways and Diseases | Detail |
|---|---|
Pathway | il-2 receptor beta chain in t cell activation;PID BioCarta;100129 |
Pathway | multiple antiapoptotic pathways from igf-1r signaling lead to bad phosphorylation;PID BioCarta;100135 |
Pathway | Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722 |
Pathway | Signaling by Insulin receptor;Reactome;REACT:498 |
Pathway | igf-1 signaling pathway;PID BioCarta;100136 |
Pathway | insulin signaling pathway;PID BioCarta;100124 |
Pathway | mtor signaling pathway;PID BioCarta;100101 |
Pathway | Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade;PANTHER;P00032 |
Pathway | Signaling events regulated by Ret tyrosine kinase;PID Curated;200058 |
Pathway | IL4-mediated signaling events;PID Curated;200018 |
Pathway | growth hormone signaling pathway;PID BioCarta;100155 |
Pathway | IL2-mediated signaling events;PID Curated;200082 |
Pathway | PI3 kinase pathway;PANTHER;P00048 |
Pathway | Aldosterone-regulated sodium reabsorption;KEGG PATHWAY;hsa04960 |
Pathway | Adipocytokine signaling pathway;KEGG PATHWAY;hsa04920 |
Pathway | Insulin signaling pathway;KEGG PATHWAY;hsa04910 |
Pathway | Insulin Pathway;PID Curated;200012 |
Pathway | S1P2 pathway;PID Curated;200181 |
Pathway | the igf-1 receptor and longevity;PID BioCarta;100115 |
Pathway | Insulin/IGF pathway-protein kinase B signaling cascade;PANTHER;P00033 |
Pathway | IGF1 pathway;PID Curated;200084 |
Pathway | mTOR signaling pathway;PID Curated;200080 |
Pathway | Signaling events mediated by PTP1B;PID Curated;200033 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | Integrins in angiogenesis;PID Curated;200109 |
Pathway | Signaling by FGFR;Reactome;REACT:9470 |
Pathway | Interleukin signaling pathway;PANTHER;P00036 |
Pathway | Type II diabetes mellitus;KEGG PATHWAY;hsa04930 |
Pathway | regulation of eif-4e and p70s6 kinase;PID BioCarta;100178 |
Disease | Type 2 diabetes;NHGRI |
Disease | Coronary artery disease, susceptibility to;OMIM |
Disease | diabetes, gestational;GAD |
Disease | adrenal androgen;GAD |
Disease | Tuberous sclerosis;FunDO |
Disease | Cancer;FunDO |
Disease | obesity;GAD |
Disease | DEVELOPMENTAL;GAD |
Disease | polycystic ovarian syndrome;GAD |
Disease | atherosclerosis, coronary;GAD |
Disease | IMMUNE;GAD |
Disease | cardiovascular disease;GAD |
Disease | Polycystic ovary syndrome;FunDO |
Disease | METABOLIC;GAD |
Disease | diabetes, type 2 sleep apnea;GAD |
Disease | glucose tolerance;GAD |
Disease | adiponectin;GAD |
Disease | colorectal cancer;GAD |
Disease | Insulin Resistance;GAD |
Disease | diabetes, type 2;GAD |
Disease | Diabetes mellitus;FunDO |
Disease | diabetes, type 1;GAD |
Disease | precocious puberty;GAD |
Disease | C-peptide insulin-like growth factor sex hormones;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | androgen levels;GAD |
Disease | insulin;GAD |
Disease | Hyperinsulinism;FunDO |
Disease | CANCER;GAD |
Disease | type 2 diabetes and other traits;GAD |
Disease | Birth Weight;GAD |
Disease | atherogenic profile;GAD |
Disease | anthropometric measuments;GAD |
Disease | REPRODUCTION;GAD |
Disease | body fat;GAD |
Disease | Hyperlipidemia;FunDO |
Disease | Obesity;FunDO |
Disease | polycystic ovary syndrome;GAD |
Disease | Diabetes mellitus, noninsulin-dependent;OMIM |
Sequence Information | |
|---|---|
Nucleotide Sequence | >3667 : length: 8743 GGTTGTTTTTCGGAGCCTCCCTCTGCTCAGCGTTGGTGGTGGCGGTGGCAGCATGGCGAGCCCTCCGGAGAGCGATGGCTTCTCGGACGTGCGCAAGGTGGGCTACCTGCGCAAACCCAA GAGCATGCACAAACGCTTCTTCGTACTGCGCGCGGCCAGCGAGGCTGGGGGCCCGGCGCGCCTCGAGTACTACGAGAACGAGAAGAAGTGGCGGCACAAGTCGAGCGCCCCCAAACGCTC GATCCCCCTTGAGAGCTGCTTCAACATCAACAAGCGGGCTGACTCCAAGAACAAGCACCTGGTGGCTCTCTACACCCGGGACGAGCACTTTGCCATCGCGGCGGACAGCGAGGCCGAGCA AGACAGCTGGTACCAGGCTCTCCTACAGCTGCACAACCGTGCTAAGGGCCACCACGACGGAGCTGCGGCCCTCGGGGCGGGAGGTGGTGGGGGCAGCTGCAGCGGCAGCTCCGGCCTTGG TGAGGCTGGGGAGGACTTGAGCTACGGTGACGTGCCCCCAGGACCCGCATTCAAAGAGGTCTGGCAAGTGATCCTGAAGCCCAAGGGCCTGGGTCAGACAAAGAACCTGATTGGTATCTA CCGCCTTTGCCTGACCAGCAAGACCATCAGCTTCGTGAAGCTGAACTCGGAGGCAGCGGCCGTGGTGCTGCAGCTGATGAACATCAGGCGCTGTGGCCACTCGGAAAACTTCTTCTTCAT CGAGGTGGGCCGTTCTGCCGTGACGGGGCCCGGGGAGTTCTGGATGCAGGTGGATGACTCTGTGGTGGCCCAGAACATGCACGAGACCATCCTGGAGGCCATGCGGGCCATGAGTGATGA GTTCCGCCCTCGCAGCAAGAGCCAGTCCTCGTCCAACTGCTCTAACCCCATCAGCGTCCCCCTGCGCCGGCACCATCTCAACAATCCCCCGCCCAGCCAGGTGGGGCTGACCCGCCGATC ACGCACTGAGAGCATCACCGCCACCTCCCCGGCCAGCATGGTGGGCGGGAAGCCAGGCTCCTTCCGTGTCCGCGCCTCCAGTGACGGCGAAGGCACCATGTCCCGCCCAGCCTCGGTGGA CGGCAGCCCTGTGAGTCCCAGCACCAACAGAACCCACGCCCACCGGCATCGGGGCAGCGCCCGGCTGCACCCCCCGCTCAACCACAGCCGCTCCATCCCCATGCCGGCTTCCCGCTGCTC GCCTTCGGCCACCAGCCCGGTCAGTCTGTCGTCCAGTAGCACCAGTGGCCATGGCTCCACCTCGGATTGTCTCTTCCCACGGCGATCTAGTGCTTCGGTGTCTGGTTCCCCCAGCGATGG CGGTTTCATCTCCTCGGATGAGTATGGCTCCAGTCCCTGCGATTTCCGGAGTTCCTTCCGCAGTGTCACTCCGGATTCCCTGGGCCACACCCCACCAGCCCGCGGTGAGGAGGAGCTAAG CAACTATATCTGCATGGGTGGCAAGGGGCCCTCCACCCTGACCGCCCCCAACGGTCACTACATTTTGTCTCGGGGTGGCAATGGCCACCGCTGCACCCCAGGAACAGGCTTGGGCACGAG TCCAGCCTTGGCTGGGGATGAAGCAGCCAGTGCTGCAGATCTGGATAATCGGTTCCGAAAGAGAACTCACTCGGCAGGCACATCCCCTACCATTACCCACCAGAAGACCCCGTCCCAGTC CTCAGTGGCTTCCATTGAGGAGTACACAGAGATGATGCCTGCCTACCCACCAGGAGGTGGCAGTGGAGGCCGACTGCCGGGACACAGGCACTCCGCCTTCGTGCCCACCCGCTCCTACCC AGAGGAGGGTCTGGAAATGCACCCCTTGGAGCGTCGGGGGGGGCACCACCGCCCAGACAGCTCCACCCTCCACACGGATGATGGCTACATGCCCATGTCCCCAGGGGTGGCCCCAGTGCC CAGTGGCCGAAAGGGCAGTGGAGACTATATGCCCATGAGCCCCAAGAGCGTATCTGCCCCACAGCAGATCATCAATCCCATCAGACGCCATCCCCAGAGAGTGGACCCCAATGGCTACAT GATGATGTCCCCCAGCGGTGGCTGCTCTCCTGACATTGGAGGTGGCCCCAGCAGCAGCAGCAGCAGCAGCAACGCCGTCCCTTCCGGGACCAGCTATGGAAAGCTGTGGACAAACGGGGT AGGGGGCCACCACTCTCATGTCTTGCCTCACCCCAAACCCCCAGTGGAGAGCAGCGGTGGTAAGCTCTTACCTTGCACAGGTGACTACATGAACATGTCACCAGTGGGGGACTCCAACAC CAGCAGCCCCTCCGACTGCTACTACGGCCCTGAGGACCCCCAGCACAAGCCAGTCCTCTCCTACTACTCATTGCCAAGATCCTTTAAGCACACCCAGCGCCCCGGGGAGCCGGAGGAGGG TGCCCGGCATCAGCACCTCCGCCTTTCCACTAGCTCTGGTCGCCTTCTCTATGCTGCAACAGCAGATGATTCTTCCTCTTCCACCAGCAGCGACAGCCTGGGTGGGGGATACTGCGGGGC TAGGCTGGAGCCCAGCCTTCCACATCCCCACCATCAGGTTCTGCAGCCCCATCTGCCTCGAAAGGTGGACACAGCTGCTCAGACCAATAGCCGCCTGGCCCGGCCCACGAGGCTGTCCCT GGGGGATCCCAAGGCCAGCACCTTACCTCGGGCCCGAGAGCAGCAGCAGCAGCAGCAGCCCTTGCTGCACCCTCCAGAGCCCAAGAGCCCGGGGGAATATGTCAATATTGAATTTGGGAG TGATCAGTCTGGCTACTTGTCTGGCCCGGTGGCTTTCCACAGCTCACCTTCTGTCAGGTGTCCATCCCAGCTCCAGCCAGCTCCCAGAGAGGAAGAGACTGGCACTGAGGAGTACATGAA GATGGACCTGGGGCCGGGCCGGAGGGCAGCCTGGCAGGAGAGCACTGGGGTCGAGATGGGCAGACTGGGCCCTGCACCTCCCGGGGCTGCTAGCATTTGCAGGCCTACCCGGGCAGTGCC CAGCAGCCGGGGTGACTACATGACCATGCAGATGAGTTGTCCCCGTCAGAGCTACGTGGACACCTCGCCAGCTGCCCCTGTAAGCTATGCTGACATGCGAACAGGCATTGCTGCAGAGGA GGTGAGCCTGCCCAGGGCCACCATGGCTGCTGCCTCCTCATCCTCAGCAGCCTCTGCTTCCCCGACTGGGCCTCAAGGGGCAGCAGAGCTGGCTGCCCACTCGTCCCTGCTGGGGGGCCC ACAAGGACCTGGGGGCATGAGCGCCTTCACCCGGGTGAACCTCAGTCCTAACCGCAACCAGAGTGCCAAAGTGATCCGTGCAGACCCACAAGGGTGCCGGCGGAGGCATAGCTCCGAGAC TTTCTCCTCAACACCCAGTGCCACCCGGGTGGGCAACACAGTGCCCTTTGGAGCGGGGGCAGCAGTAGGGGGCGGTGGCGGTAGCAGCAGCAGCAGCGAGGATGTGAAACGCCACAGCTC TGCTTCCTTTGAGAATGTGTGGCTGAGGCCTGGGGAGCTTGGGGGAGCCCCCAAGGAGCCAGCCAAACTGTGTGGGGCTGCTGGGGGTTTGGAGAATGGTCTTAACTACATAGACCTGGA TTTGGTCAAGGACTTCAAACAGTGCCCTCAGGAGTGCACCCCTGAACCGCAGCCTCCCCCACCCCCACCCCCTCATCAACCCCTGGGCAGCGGTGAGAGCAGCTCCACCCGCCGCTCAAG TGAGGATTTAAGCGCCTATGCCAGCATCAGTTTCCAGAAGCAGCCAGAGGACCGTCAGTAGCTCAACTGGACATCACAGCAGAATGAAGACCTAAATGACCTCAGCAAATCCTCTTCTAA CTCATGGGTACCCAGACTCTAAATATTTCATGATTCACAACTAGGACCTCATATCTTCCTCATCAGTAGATGGTACGATGCATCCATTTCAGTTTGTTTACTTTATCCAATCCTCAGGAT TTCATTGACTGAACTGCACGTTCTATATTGTGCCAAGCGAAAAAAAAAAATGCACTGTGACACCAGAATAATGAGTCTGCATAAACTTCATCTTCAACCTTAAGGACTTAGCTGGCCACA GTGAGCTGATGTGCCCACCACCGTGTCATGAGAGAATGGGTTTACTCTCAATGCATTTTCAAGATACATTTCATCTGCTGCTGAAACTGTGTACGACAAAGCATCATTGTAAATTATTTC ATACAAAACTGTTCACGTTGGGTGGAGAGAGTATTAAATATTTAACATAGGTTTTGATTTATATGTGTAATTTTTTAAATGAAAATGTAACTTTTCTTACAGCACATCTTTTTTTTGGAT GTGGGATGGAGGTATACAATGTTCTGTTGTAAAGAGTGGAGCAAATGCTTAAAACAAGGCTTAAAAGAGTAGAATAGGGTATGATCCTTGTTTTAAGATTGTAATTCAGAAAACATAATA TAAGAATCATAGTGCCATAGATGGTTCTCAATTGTATAGTTATATTTGCTGATACTATCTCTTGTCATATAAACCTGATGTTGAGCTGAGTTCCTTATAAGAATTAATCTTAATTTTGTA TTTTTTCCTGTAAGACAATAGGCCATGTTAATTAAACTGAAGAAGGATATATTTGGCTGGGTGTTTTCAAATGTCAGCTTAAAATTGGTAATTGAATGGAAGCAAAATTATAAGAAGAGG AAATTAAAGTCTTCCATTGCATGTATTGTAAACAGAAGGAGATGGGTGATTCCTTCAATTCAAAAGCTCTCTTTGGAATGAACAATGTGGGCGTTTGTAAATTCTGGAAATGTCTTTCTA TTCATAATAAACTAGATACTGTTGATCTTTTCTTCTGTCCCCTCCCCCCACCACTTCTGTAAGTTTCCTGCTCTATTCCCACCATTTTTTTCTGTGCACACATTATGATATATTTCATTT CCTGCATTGTCTTGAGAAAGATGGTAAGGCAAGTGAGCTGTTGCTAACCAGAAATTAAAATTCCAGTAAGTGTTTTTCATTATGACCAGGGCTATGTGTCACCTTCCCTAAGACTCTTAC CTTATCTCATATTTTTTGAGAACTTCCAGTGTTACATTATTTAACTGAATGTAATTGGCCCATTTGCCTTGGTGGGTGCTGGCCTATTAGTGATTAGTTAACAAAACACAGCGTACAGAG AGCACAGAAAAGCTTAATGACCTGCTACTGAAACACCTAGCCAGCAGTGAAAATGTTAATTCTTTTCTTGTTTGGAAAGTATACACGTCTTGGAATTTTTTCCACGTGAAAAACAAATGG CAATGAATGCATTTAAAGATATTGCCGACAGATTTTTAAATCTTTTTACCAGGAAACTTCCTAAAGGTTAAATGAATTAATGCAAATATCAGGCTCCCTCTGAGTCTGTGGGAGCCTCTA TCTCTCTATCAGGAATTCGCATCCCTACTATTGGGAGGAGCAACATTTTATTTCTCTGAACGCCTAAGCTCCCTGGGTGGGAGTGGGGACTACAAGGTAGGGGCCAGGGTTGGAGGGCAT TGTAGTGGCTGCTGCCTCCTGATGAACTGTTTGGGGACCCCAGCTCTACTCAAAAGGGAGCGGAGATAAATGGAACCCCTCACACTGCTGAGGCCCGTGTTACTGTTCATTCAGCCAGGT GGCATGTACCTCACAGACTGTTGTGCAGTGTCCGTTATTGCAGATTTTAATCATTTGCATGCTCATCAATTTCTAAGATAAATAGGGTCTAGAGTCATAAGAATCCATTGTTTTCAAGGA ACTTGCAGAATTACATCATTTCCTATTAGTAGAGAGCACTACCCATTTTGAAAATCTGATATGAAAGTTGTTTTTTACTCTTGTAAAAAAAGACTTTCTTAGTCAAACTAACTTTTCATA TTTTCAAGCATTCTGATTCATACTCTTGCTAGTGGAAGAAGAGAGCAAGCTGCCCTGCTCTTTTCCTTTGAGGACTGAAATAGTTAAAGAGAAATCAATGAACAAAGTCACTCCCAACCA TTTTCCTGTAAAGCTGGTTATTATTTCTCAAGGAACCTACACTTTGAATATGTGTTACCGAGATACCTCTACATGTGGAATTATCAACATGTTTTGAATGAGAGCAGAAATGAACAGACT GGAAAAATCTATCTCTTGGTTTCTATTTCTCTGACTTTTTGAGTCGAAAAGCATAAAGGTAGAAATTCTTATTTAAGCTGCTTCTAGTGGTGCCTGAGCTGGTTTTGATGGTGGCATCAA ACTACCGATTTAAAACTGGAAGTTGCTGGTACTCAAACCAAAAGTTCATACTCTGGCGACACGAAGGGTTTCCTTTGAGCAACGTCAGCTGCTGAGTCCTTGTGTTCAGTTCCCATTGAG GAGAGTTGGCTTTTATCCATTTCAAAGCATTTGTAGGCCAGCCAAGGGCTTTCATTATTGAGGCTTCTAGTGGCCTCTGGTTAACCTAGAAGTTAGTGGGTTTTTCTTGATGACACCAAC CTCTCACAGCGTTTTTCCTTAGAGACTTAAGCAGAGTTTTAAAATCCTCTTTTGCGAAAAGAACAAATATGTTTTATGACTTTGATGATATCTTCATTCTGGGCAAAAGAATGGCCCTAG AACCAGCTAGAAGTGAAGAGAATCCATTAATGATCAACCACCTGAGTCAATAATGAGAAATCAGTACTGATGTTACATTTGTGGCTATTTCTTGCTGACTTTCAAAGGTCAAGGACTCTT GACTAATCCAGTGACTGCAAAAATGGATCTACTAAAAGTCATCTAGCCAGAAGTAGAGATTTTTAACCTTTCTTTCCCTGGCTTTTGTCTTCTAGCTATCATTTAAATTTGAGACATTTG AAGTATTAAGAAACAATTTTTCTGTATGGTAAGAAACAGTATTTTACAATACTGAAGCCCTGTTTTATTCAATCTTGCATCTTGAATACAATATACCACAAAGTCGGAAACTTTATATTT ATTTACTGCAGGTGGTTAAAAAAAGGGGGGAAAGGGTTTCACCATCCACTGACAACGAGAGCCATGACAAATAGTATCCATGTGCAGTCTTCCAACTGCTGGTGACAATGACCCCATATT TGGTCTCATGCTGCTTTTGCAGAGCACTCTGTAGGTTAGTCCATCACACAAGGAGGCCCTGAATCCAGACACTGTGAATTAAGACCTTGGCGGGGAGAGATGTGACCCTTTTGGTAGGAA TGGGAAGAAGAATGGGTGGAAGCCAATATGAAATTTCTTCTTTGCAATGACTTGACAGGGGAGTTAATGTTCCTAGGATGCCATGAATGATGAATGTTAGTTGGAGGTAATGCTGTATAT GTGTGTGTGTGTGTGTGTGTGTGTTTGTGTGTGTGTATATATATGTGTGTGTGTATATATATGTGACATGTGTGTGTCTTTGTGTGTGTGTATATATATGTGACGTGTGTGTGGGATGTG TGTGTGTATATATAGATGAATATATACAAATATATAGATATATACACACATATATAGATATATATACACATATATAGATATATATACACACATATATAGATACACATATGTGTGTGTGTG TATATATATATATATATATATATAGATGTATAGGCTTGTGAGAAACTTGAGAGGAAGAAGCATGCTCTTCTAGGAATGTGAGGAAATATGACCTTGCCAAGACTAAAAGACCTCTAGACT GTGAGCTCAGTTATGGAGAACAAAAACAGCTTCATAGTGAGTAGAACACCGAGGATAAACACTGGGGCCATGGGTCCTTTCTGAGGCAGCGCCACAGAAGATCTTTGTGGTCCTTCCGTA GTTCTGTAAGTCTGTCTCCTAAGTATGGGTAGAGAATATGTAGCCTGTTGTGTGTCTCCCACTACTTGTAAACAGAGCATCACATTAGGGGCAGGGAGGAGGTGGAATGATATTGGAGGT GCTTAACCCTACTCGAGGAATTAATTATGAATAAAGAGCTTATAATTAGCTAACATGACTAGAAAACACATGACTTAGGTGGAGAGTTAGCTTTCTTTTCTAGTTTGTGTATGACTTGCC ATTTGTGACGTATACACCAAAAGATCTGGTGTTTTAGACTTCTGCCATTCACTTGGCATTTAAATCTCTCTTTGCTTATGCTGTTAACGAGTATGCCATAGGATAGGACAAATTCAGTAA ACAGGAAAACTTGTCCATATTTGCATAGACATTTGTAGGGTTTTTTTTTTCTTTTTCTTTTTAGAACTTCACCATTGGCTTAAGAATGTAGTTCCCAAAACAATTTTTTCTTGCAAAGTA CTTTCCTTACACCTCTTGGCTACAGGGTGGGCCAAATTAAACATATATGTATTTTCATTTAATGTATGTGCAGTTTGGTTTATCATCTTAAGATGGTGGTGCTGCCCCGGTGCTACTTCA TCTGTGTACACAAAGACCAATGCATGGTCTGTATTGCTACCAAAACATTTACTGTATATATGTTTATAACATGTATTATGTATATATGTAATGGGTGCCAGGCCAGGTATATATTTTTTA TTTAGAAGTGTTTCACTTTTCCAAGTTTTCTTTATAGTGTTATGCTTATTTTCAATTTTTTTTTTCCTGATTCTGTCTGGTACTTAGAATTGTAGTGTCTTCATCATCAATTAAAGAAAA CTGTCTAAATGAATTCATGGATGTAAATATTAGTGGTCCTTAATGTCTTTGATTGCTGGACATGAAACAAACTGCCAATTAAATTTTGCGGAGACAAAAAAAA |
Protein Sequence | >3667 : length: 1242 MASPPESDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH HDGAAALGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR GSARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPN GHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTITHQKTPSQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHR PDSSTLHTDDGYMPMSPGVAPVPSGRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNGYMMMSPSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPVES SGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEPEEGARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPH LPRKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQQQQPLLHPPEPKSPGEYVNIEFGSDQSGYLSGPVAFHSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQESTGV EMGRLGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVSYADMRTGIAAEEVSLPRATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGMSAFTRVNLSPN RNQSAKVIRADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAVGGGGGSSSSSEDVKRHSSASFENVWLRPGELGGAPKEPAKLCGAAGGLENGLNYIDLDLVKDFKQCPQECTPEPQ PPPPPPPHQPLGSGESSSTRRSSEDLSAYASISFQKQPEDRQ |