| IRS-1(h) + Grb-2(h) <==> IRS-1(h):Grb-2(h) (binding)
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IRS-1(h) + crkII(h) <==> IRS-1(h):crkII(h) (binding)
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14-3-3epsilon(v.s.) + IRS-1(h) <==> 14-3-3epsilon(v.s.):IRS-1(h) (binding)
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IL-4Ralpha(h){pY} + IRS-1(h) <==> IL-4Ralpha(h){pY}:IRS-1(h) (binding)
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InsR(h){p} + IRS-1(h) <==> InsR(h){p}:IRS-1(h) (binding)
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IRS-1(h) + Nck-2(h) <==> IRS-1(h):Nck-2(h) (binding)
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IRS-1(h) + Nck-1(h) <==> IRS-1(h):Nck-1(h) (binding)
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IRS-1(h) --Caspase-10(h)--> IRS-1-p16(h) + protein remnants (processing)
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IRS-1(h) + NTP --Jak2(v.s.)--> IRS-1(h){pY} + NDP (phosphorylation)
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IRS-1(h) + G-alpha-i2(h) <==> IRS-1(h):G-alpha-i2(h) (binding)
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IRS-1(h) + ATP --> IRS-1(h){pY} + ADP (phosphorylation)
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IRS-1(h) + ATP --IRAK1(m)--> IRS-1(h){p} + ADP (phosphorylation)
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IRS-1(h) + IGF-1R(h) <==> IRS-1(h):IGF-1R(h) (binding)
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IRS-1(h) + IRAK1(m) <==> IRS-1(h):IRAK1(m) (binding)
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IRS-1(h) + p85(m) <==> IRS-1(h):p85(m) (binding)
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Jak1(h) + IRS-1(h) <==> Jak1(h):IRS-1(h) (binding)
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p85(h) + IRS-1(h) <==> p85(h):IRS-1(h) (binding)
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Jak2(h) + IRS-1(h) <==> Jak2(h):IRS-1(h) (binding)
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IRS-1(h) + 2 ATP --> IRS-1(h){pS312}{pS616} + 2 ADP (phosphorylation)
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IRS-1(h) + 2 ATP --> IRS-1(h){pY612}{pY632} + 2 ADP (phosphorylation)
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14-3-3sigma(m.s.) + IRS-1(h) <==> 14-3-3sigma(m.s.):IRS-1(h) (binding)
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IRS1(h) --> IRS-1(h) (expression).
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IRS-1(h){pY} --PTP1B(h)--> IRS-1(h) + p (dephosphorylation)
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IFNgamma(h) --/ IRS-1(h) (decrease of abundance)
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ErbB1-p170(h){pY998} + IRS-1(h) <==> IRS-1(h):ErbB1-p170(h){pY998} (binding)
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ErbB2(h){pY1221}{pY1222} + IRS-1(h) <==> ErbB2(h){pY1221}{pY1222}:IRS-1(h) (binding)
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ErbB4(h) + IRS-1(h) <==> ErbB4(h):IRS-1(h) (binding)
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IRS1(h) --> IRS-1(h) (expression).
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IRS1(h) --> IRS1(h) (expression).
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hsa-miR-145 --/ IRS1(h) (translational repression).
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hsa-miR-126 --/ IRS1(h) (translational repression).
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