| proCaspase-8b(h) --> Caspase-8b-p41(h) + protein remnants (processing)
|
proCaspase-8b(h) --> Caspase-8b-p18(h) + protein remnants (processing)
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c-FLIP-R(h) + c-FLIP-L(h) + proCaspase-8b(h) + FADD(h) + Fas(h) <==> c-FLIP-R(h):c-FLIP-L(h):proCaspase-8b(h):FADD(h):Fas(h) (binding)
|
c-FLIP-L(h) + proCaspase-8b(h) + Fas(h) <==> c-FLIP-L(h):proCaspase-8b(h):Fas(h) (binding)
|
CASP8(h) --> proCaspase-8b(h) (expression).
|
CASP8(h) --> proCaspase-8c(h) (expression).
|
FADD(h) + proCaspase-8d(h) <==> FADD(h):proCaspase-8d(h) (binding)
|
proCaspase-8a(h) + proCaspase-8d(h) <==> proCaspase-8a(h):proCaspase-8d(h) (binding)
|
CASP8(h) --> proCaspase-8d(h) (expression).
|
CASP8(h) --> proCaspase-8e(h) (expression).
|
CASP8(h) --> proCaspase-8f(h) (expression).
|
CASP8(h) --> proCaspase-8g(h) (expression).
|
c-FLIP-L(h) + proCaspase-8(h) <==> c-FLIP-L(h):proCaspase-8(h) (binding)
|
c-FLIP-S(h) + proCaspase-8(h) <==> c-FLIP-S(h):proCaspase-8(h) (binding)
|
Apaf-1(h) + proCaspase-8(h) <==> Apaf-1(h):proCaspase-8(h) (binding)
|
BAR(h) + proCaspase-8(h) <==> BAR(h):proCaspase-8(h) (binding)
|
proCaspase-8(h) --Caspase-6(h)--> Caspase-8(h) (processing)
|
c-FLIP-L-p43(h) + FADD(h) + Fas(h) + FasL(h) + proCaspase-8(h) <==> FasL(h):Fas(h):FADD(h):proCaspase-8(h):c-FLIP-L-p43(h) (binding)
|
Hip-1(h) + proCaspase-8(h) <==> Hip-1(h):proCaspase-8(h) (binding)
|
Hippi(h) + proCaspase-8(h) <==> Hippi(h):proCaspase-8(h) (binding)
|
p38alpha(h) + proCaspase-8(h) <==> p38alpha(h):proCaspase-8(h) (binding)
|
p38alpha(h){p} + proCaspase-8(h) <==> p38alpha(h){p}:proCaspase-8(h) (binding)
|
proCaspase-8(h) + RIP3(h) <==> proCaspase-8(h):RIP3(h) (binding)
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proCaspase-8(h) --> Caspase-8-p18(h) + Caspase-8-p12(h) + protein remnants (processing)
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proCaspase-8(h) --Caspase-10(h)--> Caspase-8-p43(h) + Caspase-8-p12(h) + protein remnants (processing)
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2 proCaspase-8(h) <==> (proCaspase-8(h))2 (binding)
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proCaspase-8(h) --Caspase-3(v.s.)--> protein remnants (processing)
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Apo2L(h) + proCaspase-8(h) <==> Apo2L(h):proCaspase-8(h) (binding)
|
FasL(h) + proCaspase-8(h) <==> FasL(h):proCaspase-8(h) (binding)
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FAF1(h) + proCaspase-8(h) <==> FAF1(h):proCaspase-8(h) (binding)
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proCaspase-8(h) + Fas(h) <==> Fas(h):proCaspase-8(h) (binding)
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FADD(h) + proCaspase-8(h) <==> FADD(h):proCaspase-8(h) (binding)
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proCaspase-8(h) + FADD(m.s.) <==> proCaspase-8(h):FADD(m.s.) (binding)
|
proCaspase-8(h) + Apo2L(h) + FADD(h) + DR5(h) <==> proCaspase-8(h):Apo2L(h):FADD(h):DR5(h) (binding)
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proCaspase-8(h) + DEDD(m.s.) <==> proCaspase-8(h):DEDD(m.s.) (binding)
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proCaspase-8(h) --> TRADD(h) (binding)
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proCaspase-8(h) --> FADD(h) (binding)
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proCaspase-8(h) --> TRAF2(h) (binding)
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proCaspase-8(h) --> FAF1(m.s.) (activation)
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proCaspase-8(h) --> Caspase-8-p43(h) + protein remnants (processing)
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proCaspase-8(h) --> Caspase-8-p41(h) + protein remnants (processing)
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proCaspase-8(h) --> Caspase-8-p18(h) + protein remnants (processing)
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proCaspase-8(h) + ATP --> proCaspase-8(h){pY380} + ADP (phosphorylation)
|
proCaspase-8(h) + ATP --> proCaspase-8(h){pY} + ADP (phosphorylation)
|
c-FLIP-L-p43(h) + FADD(h) + Fas(h) + proCaspase-8(h) <==> c-FLIP-L-p43(h):FADD(h):Fas(h):proCaspase-8(h) (binding)
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c-FLIP-L-p43(h) + FADD(h) + proCaspase-8(h) + Fas(h) <==> c-FLIP-L-p43(h):Fas(h):FADD(h):proCaspase-8(h) (binding)
|
Apo2L(h) + DR5(h) + FADD(h) + proCaspase-8(h) + c-FLIP-L(h) <==> Apo2L(h):DR5(h):FADD(h):proCaspase-8(h):c-FLIP-L(h) (binding)
|
Fas(h) + FasL(h) + c-FLIP-S(m.s.) + FADD(h) + proCaspase-8(h) + c-FLIP-L-p43(h) <==> Fas(h):FasL(h):c-FLIP-S(m.s.):FADD(h):proCaspase-8(h):c-FLIP-L-p43(h) (binding)
|
proCaspase-8(h) + c-FLIP-L(m.s.) <==> proCaspase-8(h):c-FLIP-L(m.s.) (binding)
|
FasL(h) + c-FLIP-S(m.s.) + proCaspase-8(h) <==> FasL(h):proCaspase-8(h):c-FLIP-S(m.s.) (binding)
|
FasL(h) + proCaspase-8(h) + c-FLIP-L-p43(h) + c-FLIP-S(m.s.) + RIP(h) <==> FasL(h):proCaspase-8(h):c-FLIP-L-p43(h):c-FLIP-S(m.s.):RIP(h) (binding)
|
proCaspase-8(h) --> Caspase-8-p16(h) + protein remnants (cleavage)
|
proCaspase-8(h) --Caspase-3(h)--> Caspase-8-p41(h) + protein remnants (cleavage)
|
proCaspase-8(h) --Caspase-6(h)--> Caspase-8-p41(h) + protein remnants (cleavage)
|
proCaspase-8(h) --Caspase-3(h)--> Caspase-8-p43(h) + protein remnants (cleavage)
|
proCaspase-8(h) --Caspase-6(h)--> Caspase-8-p43(h) + protein remnants (cleavage)
|
Apo2L(m.s.) + proCaspase-8(h) <==> Apo2L(m.s.):proCaspase-8(h) (binding)
|
proCaspase-8(h) --> Caspase-8-p26(h) + protein remnants (cleavage)
|
proCaspase-8(h) + FADD(h) + RIP(h) + c-FLIP-L(h) <==> proCaspase-8(h):FADD(h):RIP(h):c-FLIP-L(h) (binding)
|
proCaspase-8(h) + FADD(h) + RIP(h) + c-FLIP-L(h) + c-FLIP-S(h) <==> proCaspase-8(h):FADD(h):RIP(h):c-FLIP-L(h):c-FLIP-S(h) (binding)
|
Fas(h) + FADD(h) + proCaspase-8(h) + c-FLIP-p22(m.s.) <==> Fas(h):FADD(h):proCaspase-8(h):c-FLIP-p22(m.s.) (binding)
|
Fas(h) + proCaspase-8(h) + Caspase-2-p33(h) <==> Fas(h):proCaspase-8(h):Caspase-2-p33(h) (binding)
|
Fas(h) + proCaspase-2(h) + proCaspase-8(h) <==> Fas(h):proCaspase-2(h):proCaspase-8(h) (binding)
|
proCaspase-8(h) --Caspase-3(m.s.)--> Caspase-8-p43(h) + protein remnants (cleavage)
|
proCaspase-8(h) --Caspase-3(m.s.)--> Caspase-8-p41(h) + protein remnants (cleavage)
|
proCaspase-8(h) + GMEB-1(h) <==> proCaspase-8(h):GMEB-1(h) (binding)
|
Fas(h) + FADD(h) + proCaspase-8(h) <==> Fas(h):FADD(h):proCaspase-8(h) (binding)
|
proCaspase-8(h) --> Caspase-8-p53(h) + protein remnants (cleavage)
|
proCaspase-8(h) --> protein remnants (processing)
|
proCaspase-8(h) --> Caspase-8-p44(h) + protein remnants (processing)
|
Fas(h) + proCaspase-8(h) + FADD(h) <==> Fas(h):proCaspase-8(h):FADD(h) (binding)
|
proCaspase-8(h) + FADD(h) <==> proCaspase-8(h):FADD(h) (binding)
|
RIP(m.s.) + proCaspase-8(h) <==> RIP(m.s.):proCaspase-8(h) (binding)
|
proCaspase-8(h) --> Caspase-8-p40(h) + protein remnants (processing)
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proCaspase-8(h) --> Caspase-8-p17(h) + protein remnants (processing)
|
proCaspase-8(h) --> Caspase-8-p20(h) + protein remnants (processing)
|
proCaspase-8(h) --> Caspase-8-p42(h) + protein remnants (processing)
|
proCaspase-8(h) + FADD(h) + c-FLIP-L-p43(h) + c-FLIP-S(h) <==> proCaspase-8(h):FADD(h):c-FLIP-L-p43(h):c-FLIP-S(h) (binding)
|
FLASH(m.s.) + TRAF2(h) + proCaspase-8(h) <==> FLASH(m.s.):TRAF2(h):proCaspase-8(h) (binding)
|
proCaspase-8(h) --> Caspase-8-p28(h) + protein remnants (processing)
|
proCaspase-8(h) --> Caspase-8-p45(h) + protein remnants (processing)
|
proCaspase-8(h) --> Caspase-8(h) + protein remnants (cleavage)
|
proCaspase-8(h) --> Caspase-8-p23(h) + protein remnants (cleavage)
|
CASP8(h) --> proCaspase-8(h) (expression).
|
TNFR1(h) --> proCaspase-8(h) (binding)
|
Apo2L(m.s.) --> proCaspase-8(h) (activation)
|
Daxx(h) --> proCaspase-8(h) (increase of processing)
|
Fas(h) --> proCaspase-8(h) (increase of processing)
|
Apo2L(h) --> proCaspase-8(h) (increase of processing)
|
c-FLIP-L(m.s.) --proCaspase-8(h)--> c-FLIP-L-p33(m.s.) + c-FLIP-L-p22(m.s.) (cleavage)
|
FADD(h) + proCaspase-8a(h) <==> FADD(h):proCaspase-8a(h) (binding)
|
proCaspase-8a(h) + proCaspase-8d(h) <==> proCaspase-8a(h):proCaspase-8d(h) (binding)
|
FADD(v.s.) + proCaspase-8a(h) <==> FADD(v.s.):proCaspase-8a(h) (binding)
|
proCaspase-8a(h) --> Caspase-8a-p43(h) + Caspase-8a-p12(h) (processing)
|
proCaspase-8a(h) --FasL(h)--> Caspase-8a-p20(h) + Caspase-8a-p12(h) + protein remnants (processing)
|
proCaspase-8a(h) --Apo2L(h)--> Caspase-8a-p20(h) + Caspase-8a-p12(h) + protein remnants (processing)
|
proCaspase-8a(h) + GMEB1-xbb2(h) <==> proCaspase-8a(h):GMEB1-xbb2(h) (binding)
|
proCaspase-8a(h) --> Caspase-8a-p43(h) + protein remnants (processing)
|
proCaspase-8a(h) --> Caspase-8a-p18(h) + protein remnants (processing)
|
c-FLIP-R(h) + c-FLIP-L(h) + proCaspase-8a(h) + FADD(h) + Fas(h) <==> c-FLIP-R(h):c-FLIP-L(h):proCaspase-8a(h):FADD(h):Fas(h) (binding)
|
c-FLIP-L(h) + proCaspase-8a(h) + Fas(h) <==> c-FLIP-L(h):proCaspase-8a(h):Fas(h) (binding)
|
CASP8(h) --> proCaspase-8a(h) (expression).
|
CASP8(h) --> proCaspase-8h(h) (expression).
|
CASP8(h) --> proCaspase-8-isoform-3(h) (expression).
|
CASP8(h) --> proCaspase-8-isoform-4(h) (expression).
|
CASP8(h) --> proCaspase-8-isoform-6(h) (expression).
|
CASP8(h) --> proCaspase-8-isoform-9(h) (expression).
|
