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Cancer metastasis database

Annotation category 5

Expression and regulation

Regulation From TransFac database

CD26(h) + cxcr4(h) <==> CD26(h):cxcr4(h) (binding)
cxcr4(h) + SDF-1alpha(h) <==> cxcr4(h):SDF-1alpha(h) (binding)
cxcr4(h) + SDF-1alpha(m) <==> cxcr4(h):SDF-1alpha(m) (binding)
cxcr4(h) + ATP --> cxcr4(h){p} + ADP (phosphorylation)
cxcr4(h) + Hip(h) <==> cxcr4(h):Hip(h) (binding)
CD4(h) + cxcr4(h) <==> CD4(h):cxcr4(h) (binding)
SDF-1alpha(h) + cxcr4(h) <==> SDF-1alpha(h):cxcr4(h) (binding)
beta-arrestin2(h) + cxcr4(h) <==> beta-arrestin2(h):cxcr4(h) (binding)
SDF-1alpha(m.s.) + cxcr4(h) <==> SDF-1alpha(m.s.):cxcr4(h) (binding)
cxcr4(h) --> ERK(h){p} (increase of phosphorylation)
CD45(h){pY} + cxcr4(h) <==> CD45(h){pY}:cxcr4(h) (binding)
CD4(h) + PDI(b) + cxcr4(h) <==> CD4(h):PDI(b):cxcr4(h) (binding)
cxcr4(h) + MLC(h) + Myosin-9(h) <==> cxcr4(h):MLC(h):Myosin-9(h) (binding)
cxcr4(h) + Myosin-9(h) + MLC(h) + F-actin(h) <==> cxcr4(h):Myosin-9(h):MLC(h):F-actin(h) (binding)
Myosin-9(h) + cxcr4(h) <==> Myosin-9(h):cxcr4(h) (binding)
SDF-1(h) + cxcr4(h) <==> SDF-1(h):cxcr4(h) (binding)
cxcr4(h) + DHLAG(h) <==> cxcr4(h):DHLAG(h) (binding)
cxcr4(h) + 3 ATP --> cxcr4(h){pS324}{pS325}{pS330} + 3 ADP (phosphorylation)
CXCR4(h) --> cxcr4(h) (expression).
beta-arrestin1(h) --> cxcr4(h) (increase of abundance)
beta-arrestin2(h) --> cxcr4(h) (increase of abundance)
itch(h) --> cxcr4(h) (decrease of protein stability)
CXCR4(h) --> cxcr4-isoform2(h) (expression).
cxcr4-isoform1(h) + 6 ATP --> cxcr4-isoform1(h){pS321}{pS324}{pS325}{pS}3 + 6 ADP (phosphorylation)
cxcr4-isoform1(h) + 4 ATP --> cxcr4-isoform1(h){pS324}{pS325}{pS330}{pS339} + 4 ADP (phosphorylation)
CXCR4(h) --> cxcr4-isoform1(h) (expression).

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Human U133A/GNF1H Gene Atlas  | Top