| Cks1(h) + Skp2(h) <==> Cks1(h):Skp2(h) (binding)
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cyclinE(h) + Skp2(h) <==> cyclinE(h):Skp2(h) (binding)
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p27Kip1(h){pS10}{pT187}{pT198} + Skp2(h) <==> p27Kip1(h){pS10}{pT187}{pT198}:Skp2(h) (binding)
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Fzr(h) + Skp2(h) <==> Fzr(h):Skp2(h) (binding)
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Skp2(h) + n ubiquitin(v.s.) --E1(v.s.),E2-C(h),cyclosome(x):Fzr(h)--> Skp2(h){ub(n)} (ubiquitination)
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Skp2(h) + Wee1(h) <==> Skp2(h):Wee1(h) (binding)
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Skp1(h) + Skp2(h) <==> Skp1(h):Skp2(h) (binding)
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cyclinA(h):Cdk2(h) + Skp2(h) <==> cyclinA(h):Cdk2(h):Skp2(h) (binding)
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Skp2(h) + ATP --cyclinA(b):Cdk2(x){pT160}--> Skp2(h){pS76} + ADP (phosphorylation)
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cyclinA(h) + Skp2(h) <==> cyclinA(h):Skp2(h) (binding)
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E47(h){p} + Skp2(h) <==> E47(h){p}:Skp2(h) (binding)
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Skp2(h) + Skp1(h) + E47(h) <==> Skp2(h):Skp1(h):E47(h) (binding)
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p27Kip1(h) + Skp2(h) <==> p27Kip1(h):Skp2(h) (binding)
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c-Myc(h) + Skp2(h) <==> c-Myc(h):Skp2(h) (binding)
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FOXO1A(h) + Skp2(h) <==> FOXO1A(h):Skp2(h) (binding)
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Skp2(h) + FOXO1A(m.s.) <==> Skp2(h):FOXO1A(m.s.) (binding)
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BRCA2(h) + Skp2(h) <==> BRCA2(h):Skp2(h) (binding)
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Skp2(h) --> protein remnants (degradation)
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Tob1(h) + Skp2(h) <==> Tob1(h):Skp2(h) (binding)
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Skp2(h) --/ p27Kip1(h) (decrease of abundance)
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Skp2(h) + CUL4A(m.s.) <==> Skp2(h):CUL4A(m.s.) (binding)
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Skp2(h) --> p53(h){aceK382} (decrease of acetylation)
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Skp2(h) + p300(h) <==> Skp2(h):p300(h) (binding)
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Skp2(h) + p300(m.s.) <==> Skp2(h):p300(m.s.) (binding)
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AKT-1(m.s.) + Skp2(h) <==> AKT-1(m.s.):Skp2(h) (binding)
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Skp2(h) + ATP --AKT-1(m.s.)--> Skp2(h){pS72} + ADP (phosphorylation)
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Skp2(h) + ATP --AKT-1(h)--> Skp2(h){p} + ADP (phosphorylation)
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Skp2(h) + ATP --AKT-2(m)--> Skp2(h){pS72} + ADP (phosphorylation)
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CKI-epsilon(h) + Skp2(h) <==> CKI-epsilon(h):Skp2(h) (binding)
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Skp2(h) + CKI-delta(h) <==> Skp2(h):CKI-delta(h) (binding)
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Skp2(h) + ATP --CKI(h)--> Skp2(h){pS75} + ADP (phosphorylation)
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Skp2(h) + ATP --> Skp2(h){pS64} + ADP (phosphorylation)
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Skp2(h) + 2 ATP --> Skp2(h){pS72}{pS75} + 2 ADP (phosphorylation)
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Skp2(h) + Fzr1(m.s.) <==> Skp2(h):Fzr1(m.s.) (binding)
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Skp2(h) + importin-alpha(m.s.) <==> Skp2(h):importin-alpha(m.s.) (binding)
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Skp2(h) --> Skp2(h) (translocation)
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AKT-1(h) + Skp2(h) <==> AKT-1(h):Skp2(h) (binding)
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Skp2(h) + ATP --AKT-1(h)--> Skp2(h){pS72} + ADP (phosphorylation)
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14-3-3beta(h) + Skp2(h) <==> 14-3-3beta(h):Skp2(h) (binding)
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Skp2(h) + ATP --AKT-1(h)--> Skp2(h){pT21} + ADP (phosphorylation)
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Twa1(h) + Skp2(h) <==> Twa1(h):Skp2(h) (binding)
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SKP2(h) --> Skp2(h) (expression).
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HDAC(h) --/ Skp2(h) (decrease of abundance)
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AKT-1(h){pS473} --> Skp2(h) (increase of abundance)
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AKT-1(h) --> Skp2(h) (increase of abundance)
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PTEN(h) --/ Skp2(h) (decrease of abundance)
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IGF-1(h) --> Skp2(h) (increase of abundance)
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Fzr(h) --/ Skp2(h) (decrease of abundance)
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CKI(h) --> Skp2(h) (increase of abundance)
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Skp2(h) --> Skp2(h) (translocation)
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DDB1(h) --/ Skp2(h) (decrease of abundance)
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E-cadherin(h) --/ Skp2(h) (decrease of abundance)
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BRCA2(h) + ubiquitin(h) --Skp2(h)--> BRCA2(h){ub} (ubiquitination)
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Cdk2(h) + ATP --CAK(m)--> Cdk2(h){pT160} + ADP (phosphorylation)
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Cdk2(h) + ATP --Wee1(h)--> Cdk2(h){pY15} + ADP (phosphorylation)
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Cul-1(h) + Skp1(h) + Skp2-alpha(h) <==> Cul-1(h):Skp1(h):Skp2-alpha(h) (binding)
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SKP2(h) --> Skp2-alpha(h) (expression).
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SKP2(h) --> Skp2-beta(h) (expression).
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SKP2(h) --> skp2-gamma(h) (expression).
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