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Cancer metastasis database

Annotation category 5

Expression and regulation

Regulation From TransFac database

RhoA(h):GTP + Rock-1(h) <==> RhoA(h):GTP:Rock-1(h) (binding)
Rock-1(h) --> GATA-4(m) (activation; phosphorylation)
Rock-1(h) --> GATA-5(m) (activation; phosphorylation)
Rock-1(h) + Aurora-A(h) <==> Rock-1(h):Aurora-A(h) (binding)
Rock-1(h) + Aurora-A(h) + DDX3(h) + HLR2(h) <==> Rock-1(h):Aurora-A(h):DDX3(h):HLR2(h) (binding)
Rock-1(h) --Caspase(h)--> protein remnants + Rock-1-p130(h) (cleavage)
Rock-1(h) --> protein remnants + Rock-1-p30(h) (cleavage)
Rock-1(h) --Caspase-3(m.s.)--> protein remnants + Rock-1-p30(h) (cleavage)
RhoA(m.s.):GTP + Rock-1(h) <==> RhoA(m.s.):GTP:Rock-1(h) (binding)
Rock-1(h) + Gem(h) <==> Rock-1(h):Gem(h) (binding)
caveolin-1(h) + Rock-1(h) <==> caveolin-1(h):Rock-1(h) (binding)
RhoE(m.s.) + Rock-1(h) <==> RhoE(m.s.):Rock-1(h) (binding)
ROCK1(h) --> Rock-1(h) (expression).
LIMK2(r) + ATP --Rock-1(h)--> LIMK2(r){pT505} + ADP (phosphorylation)
MLC(m.s.) + ATP --Rock-1(h)--> MLC(m.s.){pS} + ADP (phosphorylation)
Rock-1(h) --> Rock-1(h) (translocation)
Rock-1(h) + RhoE(m) <==> Rock-1(h):RhoE(m) (binding)
RhoE(m.s.) + Rock-1(h) <==> RhoE(m.s.):Rock-1(h) (binding)
ROCK1(h) --> Rock-1(h) (expression).
Rock-1(h) --> Rock-1(h) (translocation)
MLC(m.s.) + ATP --Rock-1(h)--> MLC(m.s.){pS} + ADP (phosphorylation)
RhoE(m) + 2 ATP --Rock-1(h)--> RhoE(m){pS7}{pS11} + 2 ADP (phosphorylation)

Human Primary Tumor Samples (U95)  | Top

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Human U133A/GNF1H Gene Atlas  | Top