| ABCB1(h) --> MDR-1(h) (expression).
|
MDR-1(h) --> MDR-1-p85(h) + protein remnants (cleavage)
|
MDR-1(h) --> MDR-1-p80(h) + protein remnants (cleavage)
|
MDR-1(h) --Caspase-3(h)--> MDR-1-p85(h) + protein remnants (cleavage)
|
MDR-1(h) --Caspase-3(h)--> MDR-1-p80(h) + protein remnants (cleavage)
|
MDR-1(h) + CD44(h) + ANK2(h) <==> MDR-1(h):CD44(h):ANK2(h) (binding)
|
MDR-1(h) + n ubiquitin(h) --> MDR-1(h){ub}n (ubiquitination)
|
MDR-1(h) --26S proteasome(h)--> protein remnants (degradation)
|
ABCB1(h) --> MDR-1(h) (expression).
|
LYRIC(m.s.) --> MDR-1(h) (increase of abundance)
|
